Clinical trials: Cognitive Investigation
Frailty
South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention
The goal of this feasibility randomized controlled trial is to investigate the applicability of software that aims to improve symptoms of frailty by implementing customized interventions such as physical exercise and cognitive…
- Trial name
- SUPERAGING (NCT06891573)
- Testing
- Lifestyle Management
- Where
- 3 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Seong Hye Choi, MD
Cognitive Dysfunction, Cognitive Decline
Broccoli Sprout Extract for Cognitive Function
This clinical trial aims to determine whether broccoli sprout extract improves cognitive function in adults with mild cognitive impairment and to assess its safety.
- Trial name
- NCT07334366
- Testing
- Broccoli sprout extract (BSE)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Yangsan Hospital
IBS - Irritable Bowel Syndrome
Zemedy Application for Irritable Bowel Syndrome
The purpose of the study is investigate the effectiveness of Zemedy, a mobile application that enables the digital delivery of a CBT program to people with IBS.
- Trial name
- NCT04723056
- Testing
- Use of Zemedy Application
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Stanford University
Hodgkin Disease
Hodgkin's Disease and Chemotherapy Before 40 Years
A few studies have focused on other solid cancers (colorectal, prostate). On the other hand, the study of cognitive impairment in Hodgkin's disease remains less developed, and structural and functional post-therapy MRI studies…
- Trial name
- FunC-AHOD (NCT06116929)
- Testing
- Morphological and functional magnetic resonance imaging (MRI), Neuropsychological assessment
- Where
- 4 sites in France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Obesity, Behavior, Health
Evaluation of Brain Activity Changes After a Behavior Change Weight Loss Intervention
The aim of this study is to compare brain changes in individuals with overweight or obesity enrolled in either the Noom Healthy Weight program or a matched control.
- Conditions
- Obesity, Behavior, Health, Weight Loss
- Trial name
- NCT04522245
- Testing
- Noom Healthy Weight; mobile behavior change program for weight loss., Matched Control
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
Bipolar Disorder
Investigation of Factors Associated With Preserved Cognitive Function in Bipolar Disorder
Bipolar disorder (BD) ïs the fourth leading cause of disability worldwide among young people. Differences in demographic and clinical characteristics between patients do not influence educational achievement and receipt of…
- Trial name
- NCT04454073
- Where
- Norway
- Volunteers
- 87 people
- Sponsor
- St. Olavs Hospital
Brain Injuries
Assessing Brain Changes Throughout the ABI Wellness Program
Symptoms resulting from mild/moderate trauma to the brain are as varied as the individuals who sustain them. The currently held belief is that the majority of healing and functional recovery occurs within the first two years post…
- Trial name
- NCT03438851
- Testing
- NeuroCatch Platform™
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- NeuroCatch Inc.
Moderate to Severe Dementia
Pilot Study of a Robot-assisted Intervention for the Management of Care-induced Pain in Dementia
Health care professionals lack tools to deal with acute pain in patients with moderate to severe dementia during daily nursing situations.
- Trial name
- PARODOL (NCT03591822)
- Testing
- A : Systemic evaluation of the pain and mediation with the PARO therapeutic robot, B : Systemic evaluation of the pain
- Where
- 5 sites in France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcoholism
Individualized Assessment and Treatment for Alcoholism II
The object of this study is to develop a treatment for alcohol use disorders that is more effective than current CB treatments. Through a 2009 R-21 pilot project the investigators developed a cognitive-behavioral (CB) treatment…
- Trial name
- IATP2 (NCT03233802)
- Testing
- Individualized Assess & Treatment (IATP), Packaged Cognitive-Behavioral (PCBT), Case Management (CaseM)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- UConn Health
Immune Thrombocytopenia
Cognitive Dysfunction in Chronic and Persistent Immune Thrombocytopenia
Individuals with immune thrombocytopenia (ITP) frequently report difficulties with attention and memory. The main question this study seeks to answer is: Do patients with ITP have evidence of cognitive impairment as detected by a…
- Trial name
- COGFIT (NCT06817395)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Dementia, Mild Cognitive Impairment (MCI)
Comprehensive Assessment of Neurodegeneration and Dementia
This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits.
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Subjective Cognitive Impairment, Parkinson's Disease (PD)
- Trial name
- COMPASS-ND (NCT03402919)
- Where
- 19 sites in Canada
- Volunteers
- 1,573 people, healthy volunteers welcome
- Sponsor
- McGill University
Malaria,Falciparum, Anemia in Children
Comparing Chemoprevention Approaches for School-based Malaria Control
This is an individually randomized, controlled, single blind three arm clinical trial of malaria chemoprevention strategies Arm 1: Intermittent screening and treatment (IST) - students will receive treatment if they have a…
- Trial name
- NCT05244954
- Testing
- Dihydroartemisinin-Piperaquine, Chloroquine
- Where
- Malawi
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Memory, Cognition
Effects Of Detrol LA On Memory And Cognition In Elderly Population
The primary purpose of the trial is to show that tolterodine ER has no effect on memory and other cognitive abilities in an elderly population
- Trial name
- NCT00411437
- Testing
- Tolterodine ER, Oxybutynin ER
- Where
- 9 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Opioid Use Disorder
TDCS Combined With CT In Opioid Use Disorder
The aim of the present study is to investigate the effect of prefrontal transcranial Direct Current Stimulation (tDCS) combined with cognitive training on cognitive functions in individuals with Opioid Use Disorder (OUD).
- Trial name
- OpiStim (NCT05568251)
- Testing
- transcranial Direct Current Stimulation, Cognitive training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul University
Obsessive-Compulsive Disorder
Concentrated Exposure and Response Prevention for Children With Obsessive-compulsive Disorder
The goal of this clinical trial is to evaluate the preliminary outcomes of concentrated exposure and response prevention for children with obsessive-compulsive disorder (OCD) in regular clinical practice.
- Trial name
- NCT06621381
- Testing
- Concentrated exposure and response prevention
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University Hospital
Age-Related Cognitive Decline, Age-Related Memory Disorders
Memory Improvement With Docosahexaenoic Acid Study (MIDAS)
The purpose of this study is to investigate the effect of docosahexaenoic acid (DHA, 22:6n-3) in improving cognitive functions in subjects with age-related cognitive decline.
- Trial name
- MIDAS (NCT00278135)
- Where
- 14 sites in United States
- Volunteers
- 485 people
- Sponsor
- dsm-firmenich Switzerland AG
Brain Injuries, Traumatic, Cognitive Impairment
Combined Cognitive and Vocational Interventions After Mild-to-moderate TBI: a Randomized Controlled Trial
A considerable number of patients with mild and moderate traumatic brain injury (TBI) experience long-lasting somatic, cognitive, and emotional symptoms that may hamper their capacity to return to work (RTW).
- Trial name
- NCT03092713
- Testing
- Combined cognitive (Compensatory Cognitive Training - CCT) and vocational rehabilitation (Supported Employment), Control Group
- Where
- Norway
- Volunteers
- 121 people
- Sponsor
- Oslo University Hospital
Depressive Symptoms, Quality of Life
Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda
Background Depression presents a substantial public health burden around the world. Evidence-based psychotherapy treatments (psychotherapy EBT) for depression exist but access is often limited, particularly in low- and…
- Trial name
- MBCT-VN (NCT06598579)
- Testing
- Mindfulness-based Cognitive Therapy, Treatment-as-usual involving Buddhist meditation
- Where
- Vietnam
- Volunteers
- 160 people
- Sponsor
- Vanderbilt University
COPD, Cognitive Impairment
Investigation of Square Step Exercise Applied by Telerehabilitation in Chronic Obstructive Pulmonary Disease Patients
COPD is a progressive disease associated with systemic inflammation, with many extrapulmonary outcomes such as cognitive impairment.
- Conditions
- COPD, Cognitive Impairment, Balance; Distorted
- Trial name
- COPD (NCT04841005)
- Testing
- The Square-Step Exercise Training, Strengthening Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Abant Izzet Baysal University
Accidental Falls/Prevention & Control
Neural, Cognitive, and Biomechanical Determinants of Falls in Older Adults
The goal of this clinical trial with an embedded observational phase is to evaluate whether a phenotype-guided, personalized rehabilitation program can improve fall risk and underlying neural control mechanisms in older adults…
- Trial name
- NCT07739056
- Testing
- Personalized Neurophysiological Rehabilitation, Conventional Fall-Prevention Exercise Program
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
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