Clinical trials: Cognitive Investigation
Frailty
South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention
The goal of this feasibility randomized controlled trial is to investigate the applicability of software that aims to improve symptoms of frailty by implementing customized interventions such as physical exercise and cognitive…
- Trial name
- SUPERAGING (NCT06891573)
- Testing
- Lifestyle Management
- Where
- 3 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Seong Hye Choi, MD
Older People
Impact of a Musical Intervention in Older Adults (ARA Project - Armonía Recreativa Para El Adulto Mayor)
Currently, the world is facing the challenge of population aging. At this stage of life, various deteriorations, such as cognitive decline, begin to appear, significantly impairing the quality of life.
- Trial name
- ARA (NCT06787820)
- Testing
- Music intervention
- Where
- Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Diego Portales
Social Phobia
Social Phobia Intervention Study of Mannheim
Primary objective: The purpose of this study is to examine efficacy and efficiency of a Stepped Care Program (SCP) for patients with Social Phobia in comparison to the standard cognitive therapy for Social Phobia according to…
- Trial name
- NCT00434759
- Testing
- cognitive therapy, stepped care program based on cognitive therapy
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Early Alzheimers Disease, Mild Cognitive Impairment Due to AD
A Study to Evaluate Safety and Tolerability of Different Doses and Efficacy of PQ912 in Subjects With MCI and Mild AD
This is a phase 2B multicenter, randomized, double-blind, placebo-controlled, parallel group dose finding study to evaluate the safety, tolerability and efficacy of PQ912, an inhibitor of the glutaminyl cyclase enzyme, in 250…
- Trial name
- VIVIAD (NCT04498650)
- Testing
- PQ912
- Where
- 21 sites in Denmark, Germany and 3 more
- Volunteers
- 259 people
- Sponsor
- Vivoryon Therapeutics N.V.
Cognitive Impairment
Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden
The standard or usual workup for cognitive impairment, including Alzheimer's Disease, may include brain amyloid PET with PET/CT or PET/MR imaging.
- Trial name
- Amyloid RPI (NCT06757569)
- Testing
- PET
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University Health Network, Toronto
End-Stage Renal Disease
Decreasing Depression and Anxiety and Their Effect on QoL of ESRD Patients (End-Stage Renal Disease)
This study evaluates the effect of a single cognitive-behavioral intervention (CBI) in a control group against the same CBI plus the strengthening of resiliency skills in an experimental group, on ESRD patients.
- Trial name
- ESRD (NCT03330938)
- Testing
- CBI and Resilience, Cognitive-behavioral Intervention
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Hospital Civil de Guadalajara
Brain Injury, Craniocerebral Trauma
PariS -TBI Study: Paris Severe Traumatic Brain Injury Study - 8 Years
The objective of the protocol is to pursue the long-term follow-up of a large cohort of severe traumatic brain injury patients. This outcome is to be described in terms of activity, participation, quality of life…
- Conditions
- Brain Injury, Craniocerebral Trauma, Trauma, Nervous System
- Trial name
- TCS8 (NCT02050633)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurocognitive Disorder, Etiology of Neurocognitive Disorder
Evaluation of Cognitive Impairment in the Elderly Admitted to Nursing Homes
This research aims at analysing the profile of the elderly with cognitive impairment (IC) and inquiring about the mental illnesses that cause cognitive impairment of a population (elderly admitted to nursing homes with a high…
- Trial name
- NCT05404152
- Where
- Spain
- Volunteers
- 390 people
- Sponsor
- Universidad de Murcia
Fatigue, Cognitive Impairment
Cognitive Function After Stem Cell Transplantation
The trial will evaluate the effects of an exercise program on the physical and cognitive performance of patients with hematological neoplastic diseases after high dose chemotherapy with stem cell support.
- Conditions
- Fatigue, Cognitive Impairment, Stem Cell Transplantation
- Trial name
- NCT00884338
- Testing
- Endurance exercise, Counseling
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Evaluation of Laparoscopic Hysterectomy Simulator
Evaluation of Laparoscopic Hysterectomy Simulator
This study aims to test the validity of a new educational tool in the form of a computer based video surgical simulator, that may be used to enhance the current teaching method of how to perform a hysterectomy.
- Trial name
- NCT02234856
- Testing
- Laparoscopic Hysterectomy trainer
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 45 people
- Sponsor
- Unity Health Toronto
Epilepsy
Clinical Study in Healthy Volunteers to Investigate the Neurocognitive Effects of a New Antiepileptic Drug: Brivaracetam
The primary objective of the study is to evaluate the neurocognitive effects of brivaracetam
- Trial name
- NCT00736931
- Testing
- Brivaracetam, levetiracetam, lorazepam
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UCB Pharma
TBI (Traumatic Brain Injury), Stroke
Cognitive Profile of Patients at the Sagol Center for Hyperbaric Medicine and Research
In the investigator's institute there is ongoing treatment of different patients with cognitive deficits using Hyperbaric oxygen therapy (HBOT).
- Conditions
- TBI (Traumatic Brain Injury), Stroke, Fibromyalgia, Aging
- Trial name
- NCT04287283
- Testing
- Hyperbaric Oxygen
- Where
- Israel
- Volunteers
- 2,500 people
- Sponsor
- Assaf-Harofeh Medical Center
Mild Cognitive Impairment (MCI)
Evaluation of a PMT Rehabilitation Nursing Plan for the Older Adults With MCI to Promote Cognitive Health
With the aging of the population, the number of older adults with mild cognitive impairment (MCI) has increased year by year, which has caused serious social and family burdens.
- Trial name
- NCT07089654
- Testing
- A PMT rehabilitation nursing plan, General rehabilitation nursing
- Where
- 2 sites in China
- Volunteers
- 73 people
- Sponsor
- Jinzhou Medical University
Mild Cognitive Impairment, Aortic Stenosis
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR).
- Trial name
- Neurcog TAVR (NCT05614986)
- Testing
- 5 minute Montreal Cognitive Assessment (mini MoCA)
- Where
- 4 sites in United States
- Volunteers
- 81 people
- Sponsor
- Baylor Research Institute
Schizophrenia Disorder
Assessment of Physical Activity, Balance, Muscle Strength, and Cognitive Function in Patients Diagnosed With Schizophrenia
Schizophrenia is a serious mental health condition that affects individuals' thinking, perception, emotional responses, and behavior.
- Trial name
- NCT07141966
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Lennox-Gastaut Syndrome
Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequately Controlled With Other Anti-epileptic Drugs
This study was designed to evaluate the cognitive effect, safety, and pharmacokinetics (PK) of rufinamide on Lennox-Gastaut Syndrome (LGS) inadequately controlled in pediatric participants already taking other anti-epileptic…
- Trial name
- NCT01405053
- Testing
- Rufinamide, Any other approved Antiepileptic Drug
- Where
- 47 sites in United States, Canada and 5 more
- Volunteers
- 37 people
- Sponsor
- Eisai Inc.
Alcohol Drinking, Craving
Cognitive Interference Task on Alcohol Craving and Consumption
The purpose of this study is to test a brief task of playing the game Tetris to reduce alcohol cravings and alcohol use. Women who are seen at primary care and recruited through the community will be asked to rate alcohol craving…
- Trial name
- NCT04924283
- Testing
- Tetris and Assessments, Assessment Only
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Cognition Disorders, Impaired Cognition
Digital Game: A Scale to Evaluate the Perioperative Cognitive Function
INTRODUCTION: Cognitive dysfunction is a frequent adverse event in the postoperative period, especially in elderly patients. The tests commonly used for the detection of postoperative cognitive dysfunction are time-consuming and…
- Conditions
- Cognition Disorders, Impaired Cognition, Self-Assessment
- Trial name
- MentalPlus® (NCT02551952)
- Testing
- MentalPlus®
- Where
- Brazil
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Schizophrenia, Psychotic Disorders
Investigation of Objective Cognitive Effort in Neuropsychological Evaluation of Psychotic Disorders
Psychotic disorders are characterised by a heterogeneity of symptoms, including cognitive disorders, which predict functional outcome. To date, the evaluation of cognitive functions essentially measures performance.
- Conditions
- Schizophrenia, Psychotic Disorders, Cognitive Impairment, Motivation
- Trial name
- INVESTIGECCO (NCT06782672)
- Testing
- Cardiovascular measurements, Experimental memory task, Questionnaire and semi-structured psychological interview
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Coronary Artery Disease
Web-based Psychological Intervention to Coronary Artery Heart Disease Patients
The purpose of this study is to evaluate medical cost-effectiveness, reduce the psychological risk factors( including hostility, anxiety, depression, and perceived stress) in coronary artery disease (CAD) patients and enhance the…
- Trial name
- NCT01998555
- Testing
- CBT
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
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