Clinical trials: Cognitive Manifestations
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Breast Cancer, Cognitive Symptom
MBSR During AI Therapy for Breast Cancer
This study will use non-invasive neuroimaging (i.e., MRI) to examine whether Mindfulness-Based Stress Reduction (MBSR) improves neural markers of cognitive function for postmenopausal women taking aromatase inhibitor (AI) therapy…
- Trial name
- NCT03253627
- Testing
- Health Enhancement Program, Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- New York University
Major Depressive Disorder, Cognitive Symptom
Integral Remediation for Major Depression ("Rehabilitación Integral Para la Depresión Mayor", RIDEM)
Available pharmacological and psychotherapeutic treatments are not effective for the treatment of cognitive symptoms of major depressive disorder (MDD).
- Trial name
- RIDEM (NCT03624621)
- Testing
- Functional Remediation, Computerized Cognitive Training (CCT), Psychoeducation
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital de Sant Pau
Growth Failure, Atopy
The PREWEAN Study. Weaning of Preterm Infants During the First Year of Life.
In this Austrian observational study preterm infants born with a birth weight <1500 g and a gestational age <32 weeks will be investigated at the neonatal outpatient clinic.
- Conditions
- Growth Failure, Atopy, Adiposity, Cognitive Impairment
- Trial name
- PREWEAN (NCT02936219)
- Where
- Austria
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Psoriasis, Neuroinflammation
Neuroinflammation, Affective and Cognitive Symptoms in Major Depression and Psoriasis
Objectives: To identify peripheral neuroinflammatory markers in patients suffering from major depression or psoriasis in relation to affective symptoms (anxiety, depression, irritability), fatigue and cognitive symptoms; and…
- Conditions
- Psoriasis, Neuroinflammation, Major Depressive Disorder, Cognitive Symptom
- Trial name
- INPSYDER (NCT04423471)
- Testing
- Sociodemographic variables
- Where
- Spain
- Sponsor
- Germans Trias i Pujol Hospital
Acquired Brain Injury, Cognitive Symptom
CBCR for Executive Functions in Patients With ABI in the Chronic Phase
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury
- Conditions
- Acquired Brain Injury, Cognitive Symptom, Executive Dysfunction
- Trial name
- NCT03558308
- Testing
- Computer based cognitive rehabilitation
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Katrine Sværke
Depression, Delirium
Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia
This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.
- Conditions
- Depression, Delirium, Seizures, Cognitive Disorders
- Trial name
- RCC2 (NCT02761330)
- Testing
- Ketamine, Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Cognitive Symptom, Healthy
The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults
Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults. Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive…
- Trial name
- NCT04873804
- Testing
- Transcranial Direct Current Stimulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medipol University
Breast Cancer, Cognitive Symptoms
Breast Cancer Patients' Cognitive Symptoms After Information About Chemotherapy-Related Cognitive Symptoms
Previous cross-sectional studies have shown that informing cancer patients about potential chemotherapy-related cognitive symptoms may negatively affect perceived cognitive symptoms and verbal memory performance.
- Conditions
- Breast Cancer, Cognitive Symptoms, Cognitive Decline
- Trial name
- CONTEXT (NCT04813965)
- Testing
- Written information about potential chemotherapy-related cognitive symptoms without self-affirmation, Written information about potential chemotherapy-related cognitive symptoms with self-affirmation
- Volunteers
- 148 people
- Sponsor
- Radboud University Medical Center
Sleep, Stress
The Effects of a Nutrition Supplement on Health Related Quality of Life
The purpose of this study is to evaluate the health related benefits of a superfoods nutrition supplement on health related quality of life.
- Conditions
- Sleep, Stress, Health, Subjective, Inflammation
- Trial name
- NCT04499560
- Testing
- Supplement Drink
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Cognitive Symptom, Depression
Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review
The overall aim of this study is to explore if a structured drug review will change clinical symptoms and the psychotropic drugs prescription rate in the elderly living in nursing homes (participants of the study).
- Conditions
- Cognitive Symptom, Depression, Anxiety, Neuropsychiatric Syndrome
- Trial name
- NCT03736577
- Testing
- Drug reviews with NorGeP-NH
- Where
- Norway
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Cognitive Symptom, Pre Senile Dementia
Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease
The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.
- Conditions
- Cognitive Symptom, Pre Senile Dementia, Alzheimer Disease
- Trial name
- NCT04118985
- Testing
- Cognitive rehabilitation and health behavior change intervention, Self-implementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cognitive Symptom, Evaluations, Diagnostic Self
French Language Validation of the 5-minutes Montreal Cognitive Assessment (MoCA)
The aim of the study is to validate a french version of the 5 minutes version of the Montreal Cognitive Assessment as compared to the french full version of this test.
- Trial name
- MoCATEL (NCT03232697)
- Testing
- Full version of the Montreal Cognitive Assessment, 5 minutes version of the Montreal Cognitive Assessment
- Where
- France
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Anemia, Iron-Deficiency
Iron Supplementation of Marginally Low Birth Weight Infants
Iron is essential for brain development and there is a well established association between iron deficiency in infants and poor neurological development. In Sweden, about 5% of newborns have low birth weight (< 2500 g).
- Conditions
- Anemia, Iron-Deficiency, Child Behavior Disorders, Cognitive Manifestations
- Trial name
- JOHN (NCT00558454)
- Testing
- Iron
- Where
- 2 sites in Sweden
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Umeå University
Sleep, Occupational Stress
A Proactive Intervention Promoting Strategies for Sleep and Recovery in Nurses
Considering the known challenges facing newly graduated nurses, there are possibilities to implement preventive actions. The aim of the current study was to evaluate the effects of a preventive intervention among newly graduated…
- Conditions
- Sleep, Occupational Stress, Fatigue, Behavior, Health
- Trial name
- NCT04246736
- Testing
- Bädda för Kvalitet
- Where
- 7 sites in Sweden
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cognitive Manifestations
Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates
Carotid artery plaques are known to cause stroke. Cognitive impairment is an insidious but poorly understood problem in patients with carotid plaques.
- Trial name
- ACCOF (NCT01353196)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Frail Elderly Syndrome, Bladder Disease
Perioperative Multimodal Care for Cystectomy Frail Patient
Major surgery in the elderly and frail patient is a challenge. Optimal perioperative management is essential for outcome and survival.
- Conditions
- Frail Elderly Syndrome, Bladder Disease, Nutrition Disorders, Cognitive Symptom
- Trial name
- NCT03065348
- Testing
- oral whey protein, Immunonutrition, Carbohydrate Drink
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cognitive Symptom, Schizophrenia
Touchscreen-based Cognitive Tests in Healthy Volunteers
This phase Ib study aims to evaluate applicability of touchscreen-based cognitive test battery for assessment of ketamine-induced schizophrenia-like cognitive deficits in healthy volunteers.
- Trial name
- NCT03469089
- Testing
- Ketamine 0.58, Ketamine 0.31, Modafinil
- Where
- Finland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Efavirenz, Child Behavior
Neuropsychiatric Side Effects of Efavirenz in Children Living With HIV
Efavirenz is among the preferred antiretroviral drugs for HIV-infected children. Increasing evidence shows that central nervous system side-effects in adults are more common than previously thought.
- Conditions
- Efavirenz, Child Behavior, Cognitive Symptom, Medication Adherence
- Trial name
- NCT03227653
- Testing
- Efavirenz, Nevirapine, Lopinavir-Ritonavir Drug Combination
- Where
- 6 sites in Tanzania
- Volunteers
- 144 people
- Sponsor
- Radboud University Medical Center
Cognitive Impairment, Cognitive Decline
Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders, Cognitive Symptom
- Trial name
- MoCA-Norm (NCT03246269)
- Testing
- MoCA
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Andreas Monsch