Clinical trials: Cognitive Remediation
Schizophrenia
Cognitive Remediation Program for Hospitalized in the Long Term Patients With Deficit Schizophrenia
Schizophrenia is a chronic disease with deficit in social interaction and lost of autonomy in daily life. Negative symptoms as blunted affect, avolition, social deficit and anhedonia and cognition were prognosis and functioning…
- Trial name
- IPT+ (NCT03407950)
- Testing
- IPT+, Treatment as usual
- Where
- France
- Sponsor
- University Hospital, Montpellier
Virtual Reality, Depression
Use of Virtual Reality as a Tool for Cognitive Remediation in Elderly Depressed Patients
Depression, the most common mental disorder affecting the elderly, represents a major public health issue. This pathology leads to a loss of activity and autonomy in the elderly.
- Trial name
- REVIVED (NCT07119008)
- Testing
- Virtual reality
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Schizophrenia
Cost-utility Study of a Group of Compensatory Cognitive Remediation in Schizophrenia
Significant cognitive impairment (executive functions, memory, attention) is common in schizophrenia affecting up to 80% of patients.
- Trial name
- Grecco (NCT02879604)
- Testing
- Compensatory cognitive training, Usual
- Where
- 9 sites in France
- Volunteers
- 218 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder, Psychosis
Treatment to Enhance Cognition in Bipolar Disorder
The purpose of the present study is to evaluate a neuroplasticity-oriented, computer-based cognitive remediation treatment program in patients with bipolar disorder and its effects on cognitive deficits and community functioning…
- Trial name
- TREC-BD (NCT01470781)
- Testing
- BrainWorks, Computer Control
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mclean Hospital
Schizophrenia; Psychosis, Cognitive Impairment
Efficacy of Computer-assisted Cognitive Remediation in Patients With Schizophrenia
Objective: To determine the efficacy of computer-assisted cognitive remediation (CACR) in patients with chronic schizophrenia in the community settings.
- Conditions
- Schizophrenia; Psychosis, Cognitive Impairment, Executive Function, Randomized Controlled Trial
- Trial name
- NCT04773171
- Testing
- Computer-assisted Cognitive Remediation, Conventional training programmes
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Substance-Related Disorders, Mental Disorders
Performance-based Reinforcement to Enhance Cognitive Remediation Therapy
The purpose of this study is to investigate whether monetary reinforcement for performance will enhance the effects of cognitive remediation therapy for substance users seeking treatment at an outpatient facility.
- Trial name
- NCT01633138
- Testing
- Cognitive Remediation Therapy - Standard, Cognitive Remediation Therapy plus Contingency Management
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Schizophrenia
Evaluation of a Visual Remediation Intervention for Schizophrenia
Schizophrenia is a severe psychiatric condition that is associated with significant distress and disability. In addition to cognitive difficulties in domains such as attention, memory, and problem-solving, individuals with…
- Trial name
- NCT03117452
- Testing
- Visual Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rutgers, The State University of New Jersey
Bipolar Disorder, Bipolar I Disorder
Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)
The goal of this study is to evaluate the feasibility and potential benefit of a behavioral intervention designed to improve emotion regulation in individuals with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar Affective Disorder, Bipolar Disorder I
- Trial name
- BRAINS (NCT05683431)
- Testing
- Cognitive Control of Emotion (CCE) Training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation and Functional Skills Training in Schizophrenia
This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.
- Trial name
- NCT01175642
- Testing
- Cognitive Remediation, FAST
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- National Alliance for Research on Schizophrenia and Depression
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation Therapy Within a Secure Forensic Setting
This clinical trial tests the feasibility, effectiveness and patient satisfaction with cognitive remediation therapy for patients diagnosed with schizophrenia or schizoaffective disorder within a forensic hospital.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Cognitive Deficits
- Trial name
- NCT02360813
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- Ireland
- Volunteers
- 65 people
- Sponsor
- Central Mental Hospital
Schizophrenia
Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia
The purpose of this study is to test a new computerized training program as well as to find out whether the computer training might help people who have schizophrenia.
- Trial name
- TARA (NCT01773239)
- Testing
- TARA computer-based exercises
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Schizophrenia
Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS)
Randomized, double-blind, placebo-controlled clinical trial testing the effects of 10 sessions of continuous theta burst stimulation and the effects of 16 sessions of social cognitive remediation therapy on gesture performance…
- Trial name
- BrAGG-SoS (NCT04106427)
- Testing
- continuous theta burst stimulation (cTBS), social cognitive remediation therapy (SCRT)
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcohol Use Disorder, PTSD
Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
The project will examine whether a computerized neuroscience-based cognitive training program can improve cognitive functioning and recovery outcomes among Veterans with Alcohol Use Disorder and co-occurring PTSD.
- Conditions
- Alcohol Use Disorder, PTSD, Cognitive Dysfunction
- Trial name
- NCT02929979
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation
Cognitive Remediation of Autobiographical Memory in Schizophrenia Using SenseCam®
The aim of the study is to assess the efficiency of SenseCam® in patients with schizophrenia by comparing two cognitive remediation methods of autobiographical memory.Patients and control participants will be invited to carry…
- Trial name
- RéMABSchiz (NCT02038465)
- Testing
- Questionary
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Schizophrenia
Cognitive Remediation in Schizophrenia: Efficacy and Role of Neuroplasticity in "Top-down" and "Bottom-up" Mechanisms
Schizophrenia patients have deficits of different degrees in several cognitive domains, impacting their social functioning and quality of life.
- Trial name
- NCT06482918
- Testing
- Cognitive Remediation
- Where
- Chile
- Volunteers
- 160 people
- Sponsor
- University of Chile
Chemo-brain, Chemotherapy-Related Cognitive Impairment
nCCR for Chemotherapy Related Cognitive Impairment Randomized Study
The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to treat chemotherapy-related cognitive impairment (CRCI).
- Trial name
- NCT05283629
- Testing
- Neuroplasticity-based Computerized Cognitive Remediation, Active Control Condition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Massachusetts, Worcester
Bipolar Disorder
Validation of a Cognitive Remediation Program for Bipolar Disorders
This study evaluates the effect of a new cognitive remediation program designed for patients suffering from a bipolar disorder, on cognitive functions, psychosocial functioning and neural processes.
- Trial name
- ECO-BIP (NCT02698696)
- Testing
- ECo program, CRT program, Supportive psychotherapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Schizophrenia, Schizoaffective Disorder
Adapted Cognitive/Affective Remediation for Cannabis Misuse in Schizophrenia
This study will integrate and adapt a cognitive remediation (Cognitive Enhancement Therapy [CET]) and an affect regulation (Personal Therapy [PT]) intervention for 50 individuals with schizophrenia that misuse cannabis.
- Trial name
- NCT01292577
- Testing
- CET/PT, Treatment as Usual
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Depressive Symptoms, Quality of Life
Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS
Despite its significant impact on individuals and healthcare systems, substantial gaps remain in the clinical and rehabilitative management of depression in oncology patients.
- Conditions
- Depressive Symptoms, Quality of Life, Cognitive Impairment
- Trial name
- INCEPT (NCT06589544)
- Testing
- Virtual Reality-based Cognitive Remediation (VR-COG) + Treatment as Usual (TAU), Repetitive transcranial magnetic stimulation (rTMS) + Treatment as usual (TAU), Treatment as Usual (TAU)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University Hospital of Ferrara