Clinical trials: Cognitive Remediation Therapy
Anorexia Nervosa
Cognitive Remediation Therapy for Adolescents With Anorexia Nervosa
The purpose of the current study is to investigate the role of Cognitive Remediation Therapy (CRT) as a pre-treatment intervention for adolescents who are hospitalized for Anorexia Nervosa (AN).
- Trial name
- NCT02883413
- Testing
- CRT + Teach the Parent, CRT + Contact Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Philadelphia
Memory Deficits, Electroconvulsive Therapy
Cognitive Training for Memory Deficits Associated With Electroconvulsive Therapy
Although electroconvulsive therapy (ECT) remains the most effective treatment for people with severe depression, patients may experience a significant degree of persistent and/or permanent memory problems following ECT.
- Trial name
- NCT01876758
- Testing
- Cognitive Intervention: Memory Training, Comparable general mental stimulation
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- New York State Psychiatric Institute
Schizophrenia
Effects of Cognitive Remediation Therapy on Schizophrenia Patients Through Functional Magnetic Resonance Imaging
Cognitive Remediation Therapy (CRT) can enhance cognitive performance in patients with schizophrenia improving clinical outcome. However, the neurobiological mechanism underlying cognitive improvement is not well understood.
- Trial name
- NCT01318850
- Testing
- Cognitive Remediation Therapy, Psychoeducation, Healthy controls
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Multiple Sclerosis
Computerized Cognitive Exercise Training Treatment for Adults With Multiple Sclerosis
Cognitive impairment remains a major disability for individuals with multiple sclerosis (MS). The primary objective of this study is to evaluate the efficacy for treating MS-associated cognitive deficits using a unique…
- Trial name
- NCT02141386
- Testing
- PACR (Plasticity-based, Adaptive, Computerized Cognitive Remediation)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Stony Brook University
Cognition in Schizophrenia
Treating Cognition in Schizophrenia With Atomoxetine and Cognitive Remediation
This research is being done because people with schizophrenia often have problems with thinking including learning, remembering, paying attention, and problem solving.
- Trial name
- NCT00628394
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia
Cognitive Remediation Therapy and Schizophrenia
Objectives: The purpose of this study is to determine the impact of a new Cognitive Remediation Therapy (CRT) on cognition, social autonomy, symptoms and brain functioning in patients with schizophrenia.
- Trial name
- NCT01078129
- Testing
- cognitive remediation therapy, non-CRT
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Post-Acute COVID-19 Syndrome
Cognitive Rehabilitation Therapy for COVID-19
Cognitive dysfunction, psychiatric symptoms, functional impairment, and disability following COVID-19 negatively impact Veterans' community functioning and quality of life, contribute to significant human suffering, and are…
- Trial name
- CCT-COVID (NCT06086379)
- Testing
- Compensatory Cognitive Training for COVID-19, Holistic Cognitive Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment
Computerized Memory Enhancing Treatment in MCI
The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to improve memory function in patients with Mild Cognitive Impairment (MCI).
- Trial name
- COMET (NCT05332522)
- Testing
- Neuroplasticity-based Computerized Cognitive Remediation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University Medical Center
Psychosis
Adaptation of Cognitive Enhancement Therapy for Persons at Clinical High Risk for Psychosis
The purpose of this study is to test the feasibility of a modification of CET (Cognitive Enhancement Therapy) to address symptomatic and functional difficulties associated with Clinical High Risk for Psychosis (CHR).
- Trial name
- CLUES (NCT02459210)
- Testing
- CLUES, therapy and computer games
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Beth Israel Deaconess Medical Center
Cancer of the Prostate, Cancer
Cognitive Remediation Therapy (CRT) for Adults Treated for Cancer
This study is to determine the safety, feasibility and acceptability of an 8-week cognitive remediation training (CRT) in patients treated for cancer.
- Trial name
- CaCRT (NCT03285048)
- Testing
- Cognitive Remediation Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Schizophrenia
Cognitive Remediation Therapy (CRT) in Adolescents With EOS
Cognitive Remediation Therapy (CRT) can enhance cognitive performance in schizophrenia improving functional outcome. But most of the studies have involved participants who are in average in their mid 30s, and little is known…
- Trial name
- NCT01701609
- Testing
- Cognitive Remediation Therapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Clinic of Barcelona
Schizophrenia
The Efficacy of Computerized Cognitive Remediation Therapy for Chronic Schizophrenia
The study group received antipsychotic drugs combined with Computerized Cognitive Remediation Therapy (CCRT) for 4 times/week for 45 minutes each time. The control group only received antipsychotic drugs. For a total of 12 weeks.
- Trial name
- NCT03772951
- Testing
- Cognitive Remediation Therapy, Clozapine
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai Mental Health Center
Early Psychosis
PSYCHE Cognitive Remediation & Social Recovery Study
This study is a pilot feasibility study embedded in the Early Intervention in Psychosis (EIP) services in Ireland. It explores the feasibility and acceptability of a combined cognitive remediation training and social recovery…
- Trial name
- NCT06032182
- Testing
- CRESTR Intervention, CRESTR Control
- Where
- 5 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Anorexia Nervosa
Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa is a serious life-threatening illness with a typical age of onset in adolescence; if not effectively treated, it has the potential to significantly impact adolescent development and quality of life.
- Trial name
- NCT03928028
- Testing
- Cognitive Remediation Therapy, Family Based Treatment
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Children's Hospital of Philadelphia
Schizophrenia, Schizophreniform Disorder
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
The participants in the study will receive psychiatric treatment at the UCLA Aftercare Research Program. All participants in this 12-month RCT will receive cognitive training.
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
- Trial name
- NCT05890183
- Testing
- Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Schizophrenia
Cognitive Remediation Therapy in Schizophrenia: Effects on BDNF Levels
The main objective of the study is to analyse the role of a neurotrophic factor (BDNF) as a putative biological marker of the cognitive recovery in schizophrenia following a Cognitive Remediation Therapy (CRT).
- Trial name
- NCT02341131
- Testing
- Cognitive Remediation Therapy, Psychoeducation
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression
Clinical and Economic Evaluation of Neurocognitively-Enhanced Online Cognitive Behavioural Therapy
To evaluate the clinical efficacy of online cognitive behavioural therapy supplemented with online neurocognitive remediation therapy to improve mood and cognition, decrease relapse rates and optimise work and occupational…
- Trial name
- OPTM (NCT04010643)
- Testing
- online cognitive behavioural therapy, online neurocognitive remediation therapy
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- University of Southern Denmark
Bipolar Disorder
Effects of an Integrative Psychological Program in Bipolar Disorder
Bipolar disorder is related to a high level of personal, familial, social and economic burden. There is a need for feasible adjunctive psychological interventions to use in clinical practice as a complement of pharmacotherapy to…
- Trial name
- NCT04031560
- Testing
- Integrative treatment
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
ADHD
Combined Cognitive Remediation and Behavioral Intervention for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
The objective of this study is to evaluate a novel sequenced combination of a promising, computerized cognitive training program targeting working memory (WM) deficits in children with attention-deficit/hyperactivity disorder…
- Trial name
- NCT01137318
- Testing
- Cognitive remediation and Parent Training
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Queens College, The City University of New York