Clinical trials: Cognitive Risk Assessment
Postoperative Delirium
Risk Assessment for Postoperative Delirium
Postoperative delirium (POD) - a temporary state of confusion - is a frequent complication of surgery, which most commonly occurs in elderly patients.
- Trial name
- RAPID (NCT02377115)
- Testing
- Tablet computer application
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Basel, Switzerland
Cognitive Impairment, Cognitive Impairment, Mild
Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And Risk
Many older people can experience confusion, memory problems, or a decline in their thinking after major surgery. These problems are sometimes called 'postoperative neurocognitive disorders' or PND and can affect recovery and a…
- Conditions
- Cognitive Impairment, Cognitive Impairment, Mild, Cognitive Impairment, Progressive, Anesthesia
- Trial name
- CAPSULAR (NCT07470216)
- Testing
- Montreal Cognitive Assessment, biomarkers
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Accidental Falls/Prevention & Control
Neural, Cognitive, and Biomechanical Determinants of Falls in Older Adults
The goal of this clinical trial with an embedded observational phase is to evaluate whether a phenotype-guided, personalized rehabilitation program can improve fall risk and underlying neural control mechanisms in older adults…
- Trial name
- NCT07739056
- Testing
- Personalized Neurophysiological Rehabilitation, Conventional Fall-Prevention Exercise Program
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Systolic Blood Pressure, Blood Pressure
IMST for Dementia Risk Reduction
Using a 2-arm, RCT approach, the primary goal of the study is to evaluate the feasibility and preliminary efficacy of Inspiratory Muscle Strength Training (IMST) as a non-pharmacologic intervention to reduce cardiovascular and…
- Conditions
- Systolic Blood Pressure, Blood Pressure, Depression - Major Depressive Disorder, Anxiety
- Trial name
- NCT07349706
- Testing
- Inspiratory Muscle Strength Training High-Resistance, Inspiratory Muscle Strength Training Low-Resistance
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Florida State University
Driving Habits Patients, Cognitive Impairment
Evaluation of an Educational Program in the Prevention of the Driving Risks in Patients With Neurocognitive Disorders : ACCOMPAGNE
ACCOMPAGNE study proposes to evaluate an educational program for the patient / caregiver dyad, intended to accompany the patient towards the implementation of self-regulation strategies in the driving activity.
- Trial name
- ACCOMPAGNE (NCT04493957)
- Testing
- ACCOMPAGNE Education Program, Usuals recommandations
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Disease, Aortic Valve Stenosis
Evaluating the Risk of Cognitive Impairment After Surgical and Transcatheter Aortic Valve Replacement
The investigators are conducting a pilot study to compare cognitive outcomes among Veterans with severe aortic valve stenosis who are scheduled to undergo either aortic valve replacement.
- Conditions
- Cardiovascular Disease, Aortic Valve Stenosis, Cognitive Assessments, Valve Surgery
- Trial name
- CAVIAR (NCT02971020)
- Testing
- Observational/Cognitive Assessment
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Minnesota Veterans Medical Research and Education Foundation
Menopause, Perimenopause
Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition
The goal of this clinical trial is to learn whether it is feasible to conduct a larger study comparing transdermal menopausal hormone therapy (MHT) versus no hormone therapy in menopausal women with vasomotor symptoms (hot…
- Conditions
- Menopause, Perimenopause, Vasomotor Symptoms, Cardiovascular Disease Risk Factor
- Trial name
- HERBRAVEHEART (NCT07732452)
- Testing
- Transdermal estradiol, Standard of care - non hormonal
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Healthy, Subjective Cognitive Decline (SCD)
Increasing Physical Activity Through Social Support and Stress Resilience
The goal of this clinical trial is to learn the effects of technology enhancements when combined with basic education, goal-setting, and self-monitoring to increase physical activity among older adults living alone, experiencing…
- Conditions
- Healthy, Subjective Cognitive Decline (SCD), Sedentary Behavior, Social Isolation in Older Adults
- Trial name
- I-PASS (NCT06896825)
- Testing
- Self-monitoring
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Postoperative Cognitive Dysfunction (POCD)
Cohort Study of Postoperative Cognitive Dysfunction After Off-Pump Coronary Artery Bypass Grafting
This prospective cohort study aims to investigate postoperative cognitive dysfunction in patients undergoing off-pump coronary artery bypass grafting. Eligible patients will be enrolled before surgery and followed after surgery.
- Trial name
- OPCAB-POCD (NCT07643194)
- Testing
- Off-Pump Coronary Artery Bypass Grafting
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Anzhen Hospital
Cognitive Impairment
The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
Older adults with type 2 diabetes experience cognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (based on body mass, glucose levels) are at higher…
- Trial name
- NCT03254381
- Testing
- Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Aging
Cognitive Enhancement and Risk-reduction Through Exercise for Brain-Related Outcomes
As the population ages, it is also growing more diverse. Twelve percent of older Latinos are currently diagnosed with Alzheimer's disease (AD), and it is estimated that the number of Latinos with AD will increase by 832% by 2060.
- Trial name
- CEREBRO (NCT05588778)
- Testing
- BAILAMOS™ @home/en casa, ¡En Forma y Fuerte! @home/en casa
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Bipolar Disorder, Mood Swing
Seeing the Light: Early Intervention in People at Risk for Bipolar Disorder
In the current study, the feasibility, acceptability and effectivity of a new add-on early intervention program for individuals at risk for the development of bipolar disorder is evaluated.
- Conditions
- Bipolar Disorder, Mood Swing, Prodromal Symptoms
- Trial name
- NCT06282250
- Testing
- Bright light therapy + Psycho-education + Imagery focused Cognitive Therapy, Blue-light blocking glasses + Psycho-education + Imagery focused Cognitive Therapy, Psycho-education + Imagery focused Cognitive Therapy
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Geestelijke Gezondheidszorg Eindhoven (GGzE)
Insomnia, Mental Health Functioning
Computerized Cognitive Behavioral Treatment for Insomnia: Improving Rural Veteran Access to Evidence-Based Treatment to Reduce Suicide Risk (R-Vets Sleep)
Insomnia is a major problem among veteran populations. Insomnia impacts physical and mental health functioning and is associated with reduced quality of life.
- Conditions
- Insomnia, Mental Health Functioning, Physical Health Functioning
- Trial name
- R-Vets Sleep (NCT03365024)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity)
Pilot Study of a Brain Health Program in Senior Centers
The investigators will evaluate a brain health programs in older adults with subjective cognitive decline. The primary aim of the study is to determine the credibility, expectancy, feasibility, acceptability, appropriateness…
- Conditions
- Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Risk Reduction, Healthy Lifestyle Behaviors
- Trial name
- NCT07424443
- Testing
- My Healthy Brain
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Postoperative Delirium (POD), Perioperative Neurocognitive Disorders
Ortopod CZ Pilot Study
ORTOPOD PILOT STUDY is a non-randomized, non-interventional clinical study that addresses the issue of perioperative neurocognitive disorder (deterioration of cognitive functions in the preoperative and perioperative period) and…
- Trial name
- ORTOPODCZ (NCT06869876)
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Tomas Bata Hospital, Czech Republic
Parkinson Disease, Healthy Participants
A Study of TAK-071 in People With Parkinson Disease
It is hoped that TAK-071 will help people with Parkinson's disease to walk with better balance. The main aim of the study is to check if there is a difference in how participants walk after treatment with TAK-071.
- Trial name
- NCT04334317
- Testing
- TAK-071
- Where
- 21 sites in United States
- Volunteers
- 64 people
- Sponsor
- Takeda
Cardiovascular Diseases, Respiratory Diseases
Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age…
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Mental Health Disorders, Heat Illness
- Trial name
- NCT07643571
- Testing
- WeChat Mini-program Based Heat Health Risk Early Warning Intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Cardiovascular Risk Factor, Sedentary Lifestyle
The Effects of Faculty/Staff Exercise Program
This study focuses on analyzing the data collected from participants in the Faculty/Staff Exercise Program to determine the success and quantifying the results of the program.
- Conditions
- Cardiovascular Risk Factor, Sedentary Lifestyle, Physical Activity
- Trial name
- NCT03385447
- Testing
- Physical Activity
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kent State University
Alzheimer Disease (AD), Cardio Vascular Disease
Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)
The Arlington Longitudinal Optimal Healthy Aging (ALOHA) Study is a community-based research project led by the Marymount University Center for Optimal Aging (MCOA).
- Conditions
- Alzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome
- Trial name
- ALOHA (NCT07180147)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Marymount University