Clinical trials: Cognitive Symptom
Major Depressive Disorder
Trial of Levomilnacipran in Geriatric Depression
The purpose of this study is to examine the effects of levomilnacipran (FETZIMA) compared to placebo for the treatment of depression in older adults.
- Trial name
- LMIL (NCT02466958)
- Testing
- levomilnacipran
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of California, Los Angeles
Pain
Marijuana in Combination With Opioids in Palliative and Hospice Patients
Study Objectives: Primary reduction of pain and reduction in overall opioid utilization. Secondary improvement in overall patient well being, weight stabilization with increased appetite, improved oxygen saturation, improvement…
- Trial name
- NCT03233633
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The Connecticut Hospice Inc.
Analgesia
Self-Selection and Actual Use Trial of Ibuprofen 600 mg Immediate Release/Extended Caplet
A self-selection and actual use trial to evaluate the extent to which consumers will appropriately select and use the 600 mg immediate release/extended release caplets and comply with dosing instructions.
- Trial name
- NCT01789606
- Testing
- Ibuprofen 600 mg Immediate Release/Extended Release Caplet
- Where
- 18 sites in United States
- Volunteers
- 1,083 people, healthy volunteers welcome
- Sponsor
- Pfizer
Insomnia, Apnea
Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans
The purpose of this study is to determine whether a novel intervention combining cognitive behavioral therapy for insomnia plus a positive airway pressure (PAP) behavioral adherence program provided by allied health personnel for…
- Trial name
- NCT02027558
- Testing
- Insomnia treatment & PAP adherence, General sleep education
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- VA Office of Research and Development
Pulmonary Arterial Hypertension
Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients
This is a long-term open-label safety extension to the Phase 2a study of inhaled QCC374 in adult patients with PAH. This study provides the patients who completed the QCC374X2201 study with the option to continue receiving…
- Trial name
- NCT02939599
- Testing
- QCC374
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 5 people
- Sponsor
- Novartis Pharmaceuticals
Pain
Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
Background: Inadequate pain management is common in the Emergency Department (ED). Optimal treatment of pain necessitates titration to effective dose due to the large inter-individual variability in opioid requirement.
- Trial name
- NCT01775371
- Testing
- Patient controlled analgesia (PCA), Usual Care
- Where
- 3 sites in United States
- Volunteers
- 636 people
- Sponsor
- Albert Einstein College of Medicine
Tachyarrhythmias, Syncope
Study of New Implantable Loop Recorder
The goal of this IDE clinical study is to evaluate the quality of the cardiac signal recordings obtained by the St. Jude Medical (SJM) Confirm Implantable Cardiac Monitor (device).
- Trial name
- NCT00746564
- Testing
- SJM Confirm
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Abbott Medical Devices
Brain Injury, Chronic
Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT00810615
- Testing
- Hyperbaric oxygen @ 2.4 ATA
- Volunteers
- 50 people
- Sponsor
- San Antonio Military Medical Center
Broca Aphasia
Speech Hero Home Therapy for Aphasia
The investigators will run an at-home usability study of a newly developed speech therapy app called Speech Hero with 10 individuals with Broca's aphasia in the chronic stage of stroke.
- Trial name
- NCT04471935
- Testing
- At home Speech Hero therapy app
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Flint Rehabilitation Devices, LLC
Insomnia, Chronic Pain
A Cognitive-Behaviour Therapy (CBT) Self-Management Approach for Insomnia in Chronic Pain: A Randomized Control Trial
This study will test the impact of a cognitive-behavioural self-management approach for the management of insomnia among patients with chronic pain.
- Trial name
- NCT01188460
- Testing
- Self-help manual for insomnia, Sleep diary
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Post Caesarean Analgesia
Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
The aim of this study is to compare effective analgesia with continuous wound infiltration of ropivacaine through multi-holed catheter or with morphine 100 mcg added intrathecally to spinal anesthesia, after elective Caesarean…
- Trial name
- Apcisaal (NCT02264821)
- Testing
- ropivacaine infiltration, intrathecal morphine
- Where
- Belgium
- Volunteers
- 192 people
- Sponsor
- Dr Madeleine Wilwerth
Alcohol Dependence, Bipolar Disorder
Acamprosate vs. Placebo in Bipolar Alcoholics
To conduct a double-blind, randomized, placebo-controlled outpatient clinical trial of acamprosate in individuals with alcohol dependence and bipolar disorder who are also receiving mood stabilizing medication.
- Trial name
- NCT00466661
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical University of South Carolina
Postoperative Delirium, Postoperative Cognitive Dysfunction
Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction
This research study will evaluate the effectiveness and estimate the feasibility of administering an investigational drug called 'CN-105' (the study drug), to prevent postoperative cognitive decline, delirium (serious confusion)…
- Trial name
- MARBLE (NCT03802396)
- Testing
- CN-105
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Miles Berger, MD PhD
Obesity
School-based Physical Activity Intervention for Obesity Among Adolescents With Intellectual Disability in Hong Kong
Considering that children with intellectual disability (ID) might be more vulnerable to obesity than their counterparts in the general population.
- Trial name
- NCT04463069
- Testing
- Adapted physical activity
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Alzheimer's Disease
A Study of Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease
The purpose of this study is to compare the effectiveness and safety of 2 years of treatment with galantamine as compared with placebo of patients who have mild to moderately severe Alzheimer's disease (AD).
- Trial name
- NCT00679627
- Testing
- Galantamine
- Where
- 95 sites in Czechia, Estonia and 10 more
- Volunteers
- 2,051 people
- Sponsor
- Janssen Research & Development, LLC
Traumatic Brain Injury
Brain Training to Enhance Frontal Lobe Reasoning
This study is being done to improve the ability to diagnose and to achieve higher-levels of functional recovery in soldiers and civilians who have suffered either mild Traumatic Brain Injury (TBIs) or moderate-to-severe TBIs at…
- Trial name
- NCT01552473
- Testing
- Brain Training Program 1, Brain Training Program 2
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The University of Texas at Dallas
Chronic Pain
Back on Track to Healthy Living Study
Chronic pain is a significant problem affecting millions of Americans. Research has shown that psychological treatments can help people with chronic pain manage their pain and improve their quality of life.
- Trial name
- BOT (NCT03687762)
- Testing
- Cognitive Therapy (CT), Mindfulness Meditation (MM), Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 397 people
- Sponsor
- University of Washington
Neurobehavioral Manifestations, Drug Related Sleep Disturbance
Acute and Residual Effects of Caffeinated Beer
The aim of this study is to develop information about the acute and residual effects of a new product being targeted to young adults.
- Conditions
- Neurobehavioral Manifestations, Drug Related Sleep Disturbance, Alcohol Intoxication
- Trial name
- NCT00515294
- Testing
- Caffeinated Alcoholic Beer, Non-Caffeinated Alcoholic Beer, Caffeinated Non-Alcoholic Beer
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University
Tonsillitis
Celecoxib as a Post-tonsillectomy Pain Medication
The hypothesis is that celecoxib effectively reduces pain after a tonsillectomy and reduces post-operative narcotic use. To test this hypothesis, the study is placebo controlled (sugar pill).
- Trial name
- NCT00583453
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Iowa
Alzheimer's Disease
Imaging Inflammation in Alzheimer's Disease
This study is being done to learn about inflammation and amyloid in Alzheimer's disease. A type of brain scan called a PET scan is used measure 1) inflammation and 2) abnormal accumulation of a the amount of a certain protein…
- Trial name
- NCT02831283
- Testing
- 11C-PBR28, 18F-Florbetaben, Lumbar puncture (optional)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Patrick Lao
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.