Clinical trials: Cognitive Wellness, open to volunteers
Diabetes Mellitus, Type 1
Effectiveness of a Combined mHealth-CBT Psychological Intervention to Improve Psychological Well-Being in Young Patients With T1D
Type 1 diabetes (T1D) can lead to psychological adjustments that impact the acceptance and management of this health condition, as well as the overall quality of life of patients, especially among the young.
- Trial name
- NCT06450730
- Testing
- Cognitive-Behavioral Therapy: face-to-face + app
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Microbial Colonization, Atopic Dermatitis
Nationwide Research on the Rewilding of Kindergarten Yards
Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities that is associated with altered commensal microbiota and a rising burden of immunological disorders among urban children.
- Conditions
- Microbial Colonization, Atopic Dermatitis, Asthma in Children, Allergy
- Trial name
- Vahvistu (NCT06390878)
- Testing
- Biodiversity, Playground equipment
- Where
- 2 sites in Finland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Natural Resources Institute Finland
Pain, Sickle Cell Disease
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain…
- Trial name
- PRESENCE (NCT06374238)
- Testing
- CBT+ Health coach, CBT w/o Health Coach ( self-guided), Usual Care
- Where
- 14 sites in United States
- Volunteers
- 390 people
- Sponsor
- University of Pittsburgh
Meditation, Cognitive Reappraisal
Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study
This study will evaluate how a comprehensive meditation-based program, Inner Engineering, supports teens ages 15-18 in becoming more joyful, focused, resilient, and better equipped to manage stress and thrive.
- Conditions
- Meditation, Cognitive Reappraisal, Emotional Regulation
- Trial name
- THRIVE (NCT07173608)
- Testing
- Inner Engineering Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Cancer, Cognitive Impairment
Cancer and Mild Cognitive Impairment Dyadic Intervention
The purpose of this study is to see whether programs that include both a patient and their spouse or a patient and family caregiver (known as a dyad) are helpful for families in which one member of the dyad has cancer and mild…
- Trial name
- NCT05144516
- Testing
- Behavioral: COPE +
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University
Melanoma
Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients
This clinical trial studies how people feel and live during the first two years after being treated for melanoma and whether cognitive behavioral therapy for cancer distress (CBT-C) works to improve quality of life in patients…
- Trial name
- NCT07379138
- Testing
- Best Practice, Cognitive Behavior Therapy, Electronic Health Record Review
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mayo Clinic
Generalized Anxiety Disorder
Group vs. Individual Metacognitive Therapy for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a serious and long-lasting condition that can greatly reduce quality of life, work functioning, and use of health services.
- Trial name
- NCT07579897
- Testing
- Individual Metacognitive Therapy, Group Metacognitive Therapy
- Where
- 2 sites in Norway
- Volunteers
- 64 people
- Sponsor
- Sorlandet Hospital HF
Aging, Institutionalized Older Adults
Effects of Exercise, Cognitive Training, and Their Combination in Institutionalized Older Adults
The goal of this clinical trial is to learn if physical exercise, cognitive stimulation, or a combination of both can improve mobility, cognitive function, and psychosocial well-being in institutionalized older adults aged 65 and…
- Conditions
- Aging, Institutionalized Older Adults, Cognitive Abilities, Mobility and Independence
- Trial name
- NCT07082504
- Testing
- Physical Exercise Program, Cognitive Stimulation Program, Combined Physical Exercise and Cognitive Stimulation
- Volunteers
- 140 people
- Sponsor
- University of Salamanca
Prediabetes, Brain Insulin Sensitivity
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with…
- Conditions
- Prediabetes, Brain Insulin Sensitivity, Cerebral Blood Flow, Satiety and Food Intake
- Trial name
- NCT07752225
- Testing
- Avocados
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Mindfulness, Alzheimer's Disease Related Dementia
Mindfulness to Enhance Cognitive Health in Latino Older Adults
The primary objective of the proposed research is to investigate the promise and underlying mechanisms of mindfulness training as a preventative lifestyle intervention to enhance cognitive health in Latino older adults, thereby…
- Trial name
- MLX (NCT07040904)
- Testing
- mindfulness
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Schizophrenia, Schizo Affective Disorder
REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)
The purpose of this study is to understand how different types of community-based mental health care affect thinking abilities, daily functioning, and brain activity in adults with schizophrenia and related conditions.
- Conditions
- Schizophrenia, Schizo Affective Disorder, Schizophreniform Disorders
- Trial name
- NCT07006935
- Testing
- Clubhouse Model of Psychosocial Rehabilitation for Serious Mental Illness, Usual Community-Based Mental Health Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Western Reserve University
Childhood Obesity, Childhood Obesity Pevention
School Meals in Denmark
This study looks at how a national school meal program affects the health, well-being, and learning of Danish schoolchildren aged 10 to 15 years.
- Conditions
- Childhood Obesity, Childhood Obesity Pevention, Well-being/Quality of Life, Diet Habits
- Trial name
- NCT07389421
- Testing
- School meal classes
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Psychological Distress, Quality of Life
Effectiveness of Group-based Positive Psychotherapy and Positive Cognitive Behavioral Therapy in Improving Psychological Distress, Coping Strategies, and Well-being Among Incarcerated Individuals.
The foremost idea of the proposed research is to highlight the impact of psychological distress and coping strategies on the wellbeing of individuals in incarceration.
- Conditions
- Psychological Distress, Quality of Life, Coping Strategies
- Trial name
- GB- PPT&PCBT (NCT07853352)
- Testing
- Positive Psychotherapy (PPT), Positive Cognitive Behavioral Therapy (PCBT), Waitlist Control Group
- Where
- 4 sites in Pakistan
- Volunteers
- 180 people
- Sponsor
- Bahria University
Elevated Caregiver Strain, Dementia Caregiver
Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigation: Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain
The goal of this clinical trial is to compare two group-based interventions for caregivers of persons with memory loss (N=450) delivered via telehealth.
- Conditions
- Elevated Caregiver Strain, Dementia Caregiver, Caregiver Stress
- Trial name
- LIGHTEN (NCT07868588)
- Testing
- Caring Together, Savvy Caregiver
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Massachusetts General Hospital
Burnout, Professional, Stress, Psychological
Foundational Programs to Combat Clinician Stress
This is a prospective, randomized, controlled clinical trial in which clinicians from University of Pennsylvania Health Systems (UPHS) including Penn Medicine- Lancaster General Health (LGH) and Massachusetts General Hospital…
- Conditions
- Burnout, Professional, Stress, Psychological, Stress, Physiological, Psychological Well-Being
- Trial name
- FACCTS (NCT07220421)
- Testing
- Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation, Health Education Program (HEP)
- Where
- 6 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Cancer Survivorship, Chemotherapy Side Effects
Remote Physical Activity Programming to Improve Outcomes in Cancer Survivors With and Without Type 2 Diabetes
The growing U.S. cancer survivor population is projected to hit 26M by 2040. Chemotherapy represents an effective cancer treatment but can diminish cancer survivors' quality of life-particularly cognitive function-through select…
- Trial name
- CICI-PA (NCT06725953)
- Testing
- Social Cognitive Theory-based, Technology-delivered Physical Activity Program
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Oklahoma
Aging
The Effect of NAD Supplementation on Brain Vascular Health in Aging
Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to test whether NR can also improve brain health and memory.
- Trial name
- NCT05483465
- Testing
- Nicotinamide riboside
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Mild Cognitive Impairment
Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment
This study is a validation study to evaluate efficacy of two neuroplasticity-based, computerized cognitive training programs to improve neurological and neuropsychological health in older adults with mild cognitive impairment…
- Trial name
- INHANCE-MCI (NCT07243600)
- Testing
- Computerized speed-based cognitive training, Computerized executive function cognitive training
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Posit Science Corporation
Anxiety, Anxiety Disorders and Symptoms
Video Game Play to Alleviate Adolescent Anxiety
Adolescence is a critical period for the onset and maintenance of anxiety disorders, which raises the importance of intervening early; one possibility of doing so is via digital interventions.
- Trial name
- NCT05923944
- Testing
- Eco-Rescue, Bejelewed 3
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Alcohol Misuse
The PSP Alcohol Reset Course
This observational study evaluates an internet-delivered cognitive behavioural therapy for alcohol misuse adapted for public safety personnel (PSP), called the PSP Alcohol Reset Course.
- Trial name
- NCT07873684
- Testing
- Self-Guided PSP Alcohol Reset Course
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Regina