Clinical trials: Cognitive-Behavior Treatment
Widespread Chronic Pain
The Maintaining Musculoskeletal Health Study
It is known from many studies that when patients have developed chronic widespread pain (CWP) or fibromyalgia that managing such symptoms is extremely challenging for both doctors and patients.
- Trial name
- MAmMOTH (NCT02668003)
- Testing
- Cognitive Behavioural Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Mania, Hypomania
Bipolar Intervention Study: Cognitive Interpersonal Therapy
There is a need to develop a better understanding of the early phase of bipolar disorder, and to develop and evaluate effective psychosocial interventions that assist people in this phase.
- Conditions
- Mania, Hypomania, Bipolar Affective Disorder
- Trial name
- BISCIT (NCT01315028)
- Testing
- Cognitive Interpersonal Therapy, Treatment As Usual
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Posttraumatic Stress Disorder
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
The goal of this clinical trial is to learn if cognitive-behavioral conjoint therapy (CBCT) in combination with MDMA-assisted therapy is safe and effective in people with chronic PTSD and their partners.
- Trial name
- NCT02876172
- Testing
- MDMA, CBCT, Therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Resilient Pharmaceuticals
Major Depressive Disorder
CBT+ for Depression
This study investigates the effects of a novel intervention approach, intentionally sequencing aerobic exercise immediately prior to therapy sessions (i.e., cognitive behavioral therapy [CBT]) to determine its effects on both…
- Trial name
- CBT+ (NCT06001346)
- Testing
- ActiveCBT, CalmCBT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Hoarding Disorder
Comparison of Treatment for Hoarding Disorder
This study proposes to compare two forms of treatment for Hoarding Disorder (HD), a common and impairing neuropsychiatric syndrome that has a profound impact on the lives and functioning of individuals, families, and society.
- Trial name
- NCT02040805
- Testing
- Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
- Where
- 2 sites in United States
- Volunteers
- 323 people
- Sponsor
- University of California, San Francisco
Alcohol Consumption
Network Support for Alcohol Treatment 2
The Network Support project is part of an ongoing effort to improve treatment for alcohol dependent patients. The Network Support Project is designed to help patients change their social network from one that reinforces drinking…
- Trial name
- NCT01129804
- Testing
- Coping Skills Training
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- UConn Health
Depression
Effectiveness of Telephone Versus Face-to-Face CBT in Treating People With Depression
This study will compare the effectiveness of telephone versus face-to-face administration of cognitive behavioral therapy in treating people with depression.
- Trial name
- NCT00498706
- Testing
- Telephone-administered cognitive behavioral therapy (T-CBT), Face-to-face administered CBT (FtF-CBT)
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Bipolar Disorder, Anxiety Disorders
Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
The specific goal of this research study is to investigate the feasibility, acceptability, and preliminary efficacy of a transdiagnostic, cognitive-behavioral therapy developed specifically to target common core processes across…
- Trial name
- NCT01892306
- Testing
- UP CBT, Treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Depression
Group Depression Treatment for Autistic Youth
Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated…
- Conditions
- Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
- Trial name
- NCT05430022
- Testing
- Autism-adapted Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University Medical Center
Adherence, Treatment, Retention
KNA Proof-of-Concept
The intervention program proof-of-concept was assessed as a single-arm, within-subjects clinical study with a target enrollment of 10 participants with possible or probable amnestic MCI.
- Conditions
- Adherence, Treatment, Retention, Cognitive Impairment, Mild
- Trial name
- NCT04968041
- Testing
- Motivational Interviewing-Cognitive Behavioral Therapy Ketogenic Nutrition Adherence Program
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Florida State University
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts
The investigators are conducting this study to learn more about the cognitive and attentional processes among individuals with three types of repetitive negative thinking (RNT): mental rituals (as seen in obsessive compulsive…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT04225624
- Testing
- Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Obsessive-compulsive Disorder
D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
The investigators are conducting a randomized double-blind placebo-controlled study to assess the efficacy of d-cycloserine augmentation of cognitive-behavioral therapy for the treatment of pediatric obsessive compulsive…
- Trial name
- NCT01411774
- Testing
- Cognitive-behavioral therapy, d-cycloserine
- Where
- 2 sites in United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Schizophrenia, Schizoaffective Disorder
A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
Varenicline (Chantix) is a smoking cessation treatment that was approved in 2006 by the FDA for treatment of nicotine dependence and may be particularly beneficial in smokers with schizophrenia or bipolar disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Smoking
- Trial name
- SCRP (NCT00621777)
- Testing
- Varenicline
- Where
- 10 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Tinnitus
Cognitive Behavioral Therapy (CBT) for Tinnitus
This study examined how useful it is to teach veterans coping skills for dealing with tinnitus, also called ringing in the ears.
- Trial name
- NCT00724152
- Testing
- Cognitive Behavioral Therapy, Tinnitus Education
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- US Department of Veterans Affairs
Panic Disorder
Org 25935 Versus Placebo as Augmentation to Cognitive-behavioral Therapy to Treat Panic Disorder (P05705)
The purpose of this study is to evaluate the effectiveness of Org 25935 vs. placebo given in combination with cognitive-behavioral therapy (CBT) to reduce the symptoms of panic disorder.
- Trial name
- NCT00725725
- Testing
- Cognitive-behavioral therapy, Org 25935
- Volunteers
- 46 people
- Sponsor
- Merck Sharp & Dohme LLC
Food Habits
Modifications in the Eating Habits of Adolescents of Secondary Education as a Result of a Nutritional Intervention
The objective of the study was to demonstrate the efficacy of a nutritional intervention based on the Social Cognitive Theory and the Transtheoric Model in the favorable modification of eating habits in adolescents of secondary…
- Trial name
- NCT03206476
- Testing
- Nutritional intervention based on the SCT and the TM, Nutritional information
- Where
- Mexico
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Gabriela Macedo Ojeda
Multiple Sclerosis
Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue
This clinical trial will compare the effectiveness of 3 treatments for fatigue in Multiple Sclerosis: 1) a commonly used behavioral treatment strategy (telephone-based cognitive behavioral therapy), 2) a commonly used medication…
- Trial name
- COMBO-MS (NCT03621761)
- Testing
- Telephone-based Cognitive Behavioral Therapy, Modafinil
- Where
- 2 sites in United States
- Volunteers
- 343 people
- Sponsor
- University of Michigan
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms
The objective of this study is to identify Acute Coronary Syndromes (ACS) patients' specific needs and preferences for depression treatment via in-person or virtual individual interviews to (a) guide MBCT adaptation; and identify…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT03878160
- Testing
- Individual Interview
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alcohol Use Disorder
Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders
Evaluate the efficacy of CBT4CBT and clinician-delivered CBT relative to standard treatment for reducing alcohol use
- Trial name
- NCT02742246
- Testing
- Individual clinician-provided CBT, CBT4CBT
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Yale University
Pulmonary Hypertension, Insomnia
Cognitive Behavioral Therapy and Light Therapy
Cognitive behavioral therapy (CBT-I) is a common treatment for insomnia that does not use medications. While CBT-I is effective for insomnia, it does not tend to improve the waking symptom of fatigue.
- Conditions
- Pulmonary Hypertension, Insomnia, Fatigue
- Trial name
- NCT05337943
- Testing
- CBT-I, Bright Light Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Pennsylvania