Clinical trials: Cognitive-Behavior Treatment
Major Depressive Disorder
Evaluation of a Male-specific Psychotherapeutic Program for Major Depressive Disorders
This project aims to evaluate a male-specific psychotherapeutic program (MSPP) for MDD based on cognitive behavioral therapy (CBT). The primary goal is to test the superiority of the MSPP.
- Trial name
- MSPP-MDD (NCT05435222)
- Testing
- Male-specific psychotherapeutic program (MSPP), Cognitive beahvioral therapy (CBT)
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- Andreas Walther
Chronic Pain, Low Back Pain
Meditation-CBT for Opioid-treated Chronic Low Back Pain
Chronic low back pain (CLBP) is one of the most common, costly and disabling conditions. It is often refractory to treatment, with patients requiring long-term opioid therapy.
- Trial name
- NCT01775995
- Testing
- Meditation-CBT Intervention + Usual Care, Usual Care Alone
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Wisconsin, Madison
Chest Pain
Treatment of Non-Cardiac Chest Pain With Imipramine or Cognitive-Behavioral Therapy
Approximately 75,000-150,000 patients each year in the United States undergo intensive cardiac evaluations for symptoms of angina-like chest pain that produce no positive findings.
- Trial name
- NCT00005575
- Testing
- Imipramine, Cognitive-behavior therapy
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy, CVA
Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.
DELPhI software developed for the analysis of EEG recordings in response to magnetic stimulation in relation to clinical data.
- Conditions
- Healthy, CVA, Hemorrhage, TBI (Traumatic Brain Injury)
- Trial name
- NCT04095377
- Testing
- No intervention, this is a retrospective study.
- Where
- Israel
- Volunteers
- 875 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Insomnia
Cracking the Code to Better Sleep: A Pioneering Study on Remote Support for Insomnia Relief
The goals of this clinical trial are to assess the feasibility of an internet-based Cognitive Behavioral Therapy for Insomnia (CBT-I) and Motivation Interviewing (MI) intervention for individuals aged 18 to 64 with mild to…
- Trial name
- NCT06211075
- Testing
- Cognitive Behavioural Therapy for Insomnia with Motivational Interviewing
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Overcome
Sensory Disorders, Autism
Exposure Therapy for Auditory Sensitivity in Autism
Auditory hyper-reactivity affects up to 66% of children with autism spectrum disorder (ASD) and has been linked to greater stress and anxiety for children and their families.
- Conditions
- Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities
- Trial name
- NCT03206996
- Testing
- Exposure therapy, Psycho-education, Caregiver education/home program development
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Florida
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Opioid-Related Disorders
Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings
Treating Opioid Patients' Pain and Sadness (TOPPS) focuses on the relationship of pain, depression, opioid and other substance misuse, and functioning.
- Trial name
- TOPPS (NCT03698669)
- Testing
- Treating Opioid Patients' Pain and Sadness (TOPPS), Health Education (HE)
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- Boston University
Depression, Anxiety Disorders, Psychiatric Inpatients
Cognitive Behavior Therapy in Psychiatric Inpatient Care
The current project aims to evaluate the extent to which psychological interventions based on Cognitive Behavioral Therapy (CBT), provided within the framework of care, may be helpful for patients in psychiatric inpatient care.
- Trial name
- NCT07503951
- Testing
- Cognitive Behavioral Therapy, treatment as usual (TAU) (Control Group)
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Region Stockholm
Tobacco Use Cessation
Study of the Effectiveness of a Virtual Reality Treatment in the Management of Smoking Cessation
Tobacco is an addiction with serious consequences: somatic, psychiatric... The number of requests for treatment for tobacco addiction is gradually increasing from year to year, but conventional treatments have limited…
- Trial name
- 3DSmoke (NCT04610931)
- Testing
- Virtual Reality-Enhanced Cognitive Behavioral Therapy (VR-CBT), cognitive behavior therapy
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Clermont-Ferrand
Major Depressive Disorder, Traumatic Brain Injury
Adapted Cognitive Behavioral Treatment for Depression in Patients With Moderate to Severe Traumatic Brain Injury
Cognitive behavioral therapy for major depressive disorder (MDD) was adapted for individuals with moderate to severe traumatic brain injury (TBI) (CBT-TBI). A structured, treatment manual was developed.
- Trial name
- NCT03307070
- Testing
- Cognitive Behavioral Therapy for individuals with TBI, Waitlist Control
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Massachusetts General Hospital
Chronic Primary Pain
Network-Based vs. Standardized Cognitive Behavioral Therapy in Chronic Primary Pain
Cognitive-behavioral therapy (CBT) has been shown to be an effective treatment for chronic primary pain (CPP), but overall effect sizes are small to moderate.
- Trial name
- NCT06784141
- Testing
- personalized Cognitive Behavior Therapy including third-wave, standardized Cognitive Behavior Therapy including third-wave
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Prof. Dr. Julia Glombiewski
Alcohol Use Disorder
Severe Alcohol-use Disorder: a tDCS and Response Inhibition Training Intervention
Most severe forms of alcohol-use disorder are thought to reflect an abnormal interplay between two neural systems: an overly active impulsive one driven by immediate rewards prospects and a weak reflective one, tuned on long-term…
- Trial name
- ALCOSTIM (NCT03447054)
- Testing
- Combined TDCS active and ICT active, Combined TDCS active and ICT inactive
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Brugmann University Hospital
ADHD
Cognitive Remediation in ADHD Children : Comparison Between Three Therapeutic Strategies : Cognitive Remediation With a Virtual Classroom Software and Methylphenidate and Supportive Psychotherapy
The Attention Deficit Disorder with or without Hyperactivity (ADHD) is one of the most frequently found disorder in children. It is characterized by a triad of symptoms involving attention deficit, hyperactivity and impulsivity…
- Trial name
- RECOGNITA (NCT01821170)
- Testing
- Methylphenidate, cognitive remediation, supportive psychotherapy
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Anxiety Disorders
Internet-based Cognitive Behavioral Therapy (CBT) for Adolescents With Anxiety Disorders
Cognitive behavioral therapy (CBT) is a well-documented and effective method for the treatment of children and adolescents with anxiety disorders.
- Trial name
- NCT02535403
- Testing
- ICBT
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- University of Aarhus
Suicidal Ideation, Depression
Digital Cognitive Behavior Therapy Program for Suicide Prevention
This study evaluates the efficacy of Thrive, a computerized cognitive behavior therapy program, to reduce depression and anxiety symptoms and to reduce suicidal thinking among adults.
- Conditions
- Suicidal Ideation, Depression, Anxiety
- Trial name
- TM2 (NCT03595254)
- Testing
- Thrive
- Where
- United States
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- Montana State University
Anxiety, Depression
Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Background and Study Aims: Secondary school students are reporting unprecedented levels of anxiety and mood difficulties. To ensure that the needs of all young people are met, there is a need to evaluate more accessible forms of…
- Conditions
- Anxiety, Depression, Internalizing Problems, Low Mood
- Trial name
- NCT06188962
- Testing
- CBT-informed school-based counselling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Depression
Emotional and Cognitive Control in Late-Onset Depression
This study may help identify how abnormalities in brain systems that control the ability to ignore irrelevant information may contribute to the development of depression in older adults.
- Trial name
- NCT01728194
- Testing
- Escitalopram, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Depressive Disorder, Treatment-Resistant
rTMS With and Without iCBT For the Treatment of Resistant Depression (TRD)
This is a prospective, two-arm randomized controlled trial. 100 patients diagnosed with resistant depression in psychiatric care clinic in Edmonton, Alberta, Canada will be randomized to one of two conditions: (1) enrolment in…
- Trial name
- NCT04239651
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Internet-Delivered Cognitive Behavior Therapy (iCBT)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Alberta
Major Depression
Efficacy of 18-Months of Antidepressive Medication Plus CBT or Dynamic or Supportive Psychotherapy for Recurrent Major Depression
Major Depressive Disorder affects approximately 16% of the adult population over the lifetime. Controlled studies indicate that short-term antidepressive medications or psychotherapy produce full remission in only about 46% of…
- Trial name
- NCT00220623
- Testing
- antidepressant medications, flexible drug choice, CBT, Psychodynamic or Supportive Psychotherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
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