Clinical trials: Cognitive-Behavior Treatment
Adjustment Disorder, Anxiety
Online MBCT for Adjustment Disorder During COVID-19: Efficacy, Mechanisms, and RCT
This study tested a 4-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing adjustment disorder during the COVID-19 pandemic.
- Conditions
- Adjustment Disorder, Anxiety, Depressive
- Trial name
- NCT07128017
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), Progressive Muscle Relaxation (Internet-delivered), No Intervention - Waitlist Control
- Where
- Poland
- Volunteers
- 301 people
- Sponsor
- University of Warsaw
Sickle Cell Disease, Chronic Pain
Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease
The primary aim of this study is to test the feasibility and acceptability of implementing a multimedia computerized cognitive behavioral therapy (cCBT) program for reducing SCD pain symptoms in a single-arm pilot pragmatic…
- Trial name
- CALM-SCD (NCT03029468)
- Testing
- cognitive behavioral therapy, eEducation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Pittsburgh
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Many patients with Major Depressive Disorder (MDD) and generalized Social Anxiety Disorder (gSAD) are treated with cognitive behavioral therapy (CBT) but few have meaningful improvement.
- Trial name
- NCT03175068
- Testing
- CBT, ST
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Depressive Symptoms
TreadWill, an Automated Intervention for Depressive Symptoms
TreadWill is a fully automated digital intervention that provides a multi-modal treatment for depressive symptoms. It includes: 1. Slides and interactive text-based conversations based on Cognitive Behavioral Therapy (CBT); 2.
- Trial name
- NCT04703491
- Testing
- Interactive and full-featured intervention, Feature-limited CCBT, Waitlist control
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Indian Institute of Technology Kanpur
Insomnia
Predictors of Response to Insomnia Treatments for Gulf War Veterans
The purpose of this study is to evaluate the efficacy and effectiveness of Behavioral Therapy (BT) and Cognitive Therapy (CT) in Gulf War Veterans with insomnia. The Primary Outcome measure is the Insomnia Severity Index (ISI).
- Trial name
- NCT03208049
- Testing
- Behavioral Therapy (BT), Cognitive Therapy (CT)
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Obsessive-Compulsive Disorder
Four-day Intensive Treatment Versus Standard Cognitive Behavioral Therapy for Adults With Obsessive-compulsive Disorder
The goal of this clinical trial is to compare a novel, condensed version of cognitive behavioral therapy (Bergen 4-Day Treatment, B4DT) to the gold standard psychological treatment (gold-standard CBT) for obsessive compulsive…
- Trial name
- NCT05608278
- Testing
- Bergen 4-Day Treatment (B4DT), Gold standard cognitive behavioral therapy (gold standard CBT)
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Suicidal Thoughts and Behaviors
Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention
Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual.
- Trial name
- NCT06809348
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Insomnia
dCBTi for Adults With ADHD
The current study aims to evaluate the efficacy and feasibility of a digital application-based CBTi treatment devised for adults with ADHD and insomnia compared to self-monitoring and sleep hygiene control condition.
- Trial name
- NCT05133908
- Testing
- Sleep Hygiene and Self-Monitoring Control, dCBTi-ADHD
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Depression, Mental Disorder in Adolescence
Study of Web- Based Cognitive Behavioral Therapy for Depressed Korean Adolescents
The purpose of this study is to develope web-based cognitive behavioral therapy for Korean adoldescents who have a mild depression.
- Conditions
- Depression, Mental Disorder in Adolescence, Cognitive Behavioral Therapy
- Trial name
- wogyeokdajim (NCT02072304)
- Testing
- web-based CBT, supportive care
- Where
- 3 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Hallym University Medical Center
Obsessive-Compulsive Disorder
The Use of D-Cycloserine to Augment CBT for Pediatric OCD
Pediatric obsessive compulsive disorder (OCD) is a relatively common and often severe condition that can become chronic if untreated.
- Trial name
- DCS (NCT01687140)
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Pedophilia
Prevent It 2.0/GPP -iCBT to Reduce the Risk of Committing Child Sexual Abuse
Child sexual abuse is a large-scale global problem, and with the internet and communication technologies enabling new ways to sexually abuse children, the problem is drastically increasing.
- Trial name
- NCT05663047
- Testing
- Prevent It 2.0, Waitlist
- Where
- Sweden
- Volunteers
- 203 people
- Sponsor
- Karolinska Institutet
Depression, Anxiety Disorders
Therapist Adherence to Cognitive-behavioral Therapy
An observational web-based survey on therapist adherence to evidence-based cognitive-behavioral therapy (CBT) in the perspective of their patients with depression or anxiety disorders in psychiatric outpatient care in Stockholm…
- Trial name
- NCT04119258
- Testing
- Cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Karolinska Institutet
Traumatic Brain Injury, Depression
Treatment of Post-TBI Depression
Randomized clinical trial that compares the effects of cognitive behavioral therapy (CBT) and supportive psychotherapy for depression.
- Trial name
- NCT00211835
- Testing
- Cognitive behavioral therapy, Supportive psychotherapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Perceived Burdensomeness, Suicidal Ideation
Evaluation of a Brief, Scalable Module to Mitigate Suicidal Ideation Among Youth (Phase 2)
This project embeds the "Give to Others" (GO) talk therapy module in a standard, outpatient therapy protocol to demonstrate target engagement in the context of ongoing clinical care and testing the ability of the GO module to…
- Trial name
- NCT07847008
- Testing
- Safety Planning, Give to Others (GO) Module, MATCH (Modular Approach to Therapy for Children) - Anxiety and Depression Modules
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Florida International University
Effect of Superstarch on Soccer Performance
Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game
To assess the efficacy of a hydrothermally modified starch supplement (Superstarch made byGeneration UCAN) vs isoenergetic placebo (glucose) on exercise performance, execution of specific soccer skills, and on cognitive function…
- Trial name
- NCT02667340
- Testing
- Superstarch
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Insomnia, Fatigue
Cognitive Behavioral Therapy +/- Armodafinil for Insomnia and Fatigue Following Chemotherapy
This is a four-arm, randomized, controlled, clinical trial examining the efficacy of of cognitive behavioral therapy (CBT)-I and armodafinil in reducing insomnia in 226 female breast cancer patients who report sleep disturbances…
- Conditions
- Insomnia, Fatigue, Breast Cancer
- Trial name
- NCT01091974
- Testing
- armodafinil, CBT-I
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- University of Rochester
Prostate Cancer, Prostatic Neoplasms
PROWESS (PROstate Cancer Wearables Exercise and Structured Supports): A Pilot Supportive Care Intervention
The goal of this research study is to conduct an open pilot of a behavioral change intervention called PROstate Cancer Wearables, Exercise, and Structured Supports (PROWESS) for integrating health behavior change tools and to…
- Trial name
- NCT05755490
- Testing
- PROWESS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Medically Unexplained Chronic Fatigue, Chronic Fatigue Syndrome
Fatigue Self-Management in Primary Care
This study will evaluate, in a primary care setting, the effectiveness of a brief self-management behavioral treatment in patients with medically unexplained chronic fatigue.
- Trial name
- NCT00997451
- Testing
- Cognitive-behavioral self-management, Symptom monitoring
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Stony Brook University
Mental Disorders
Positive Affect and Mental Imagery in the Process of Cognitive Behavioural Therapy
Background: Research findings suggested that people with mental disorders show a dysfunctional upregulation of negative affect (NA) but at the same time a dysfunctional downregulation of positive affect (PA) as distinct…
- Trial name
- PACIfIC (NCT03767101)
- Testing
- Cognitive behavioral therapy
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Ulrike Willutzki
Depression and Quality of Life Related to the Coronavirus Pandemic
ICBT for Mental Health Problems Related to the Coronavirus Pandemic
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme a on adult mental health problems related to the current coronavirus pandemic.
- Trial name
- NCT04424212
- Testing
- Intervention group CoronaCope
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Linkoeping University
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