Clinical trials: Cohort
Perioperative Medicine, Hip Fractures
Preoperative Echocardiography in Patients With Hip Fracture
Aim of the study was to assess whether preoperative echocardiography affects time to surgery, length of hospital stay and in hospital mortality in patients undergoing hip fracture surgery.
- Conditions
- Perioperative Medicine, Hip Fractures, Echocardiography
- Trial name
- NCT05869396
- Testing
- echocardiography
- Where
- Italy
- Volunteers
- 255 people
- Sponsor
- University of Florence
Ischemic Stroke
Multi-center, Prospective, Cohort Study to Evaluate the Relationship of Stroke Recurrence and Anti-platelet Resistance in Ischemic Stroke Patients
This cohort study will evaluate the relatiobship of stroke recurrence and anti-platelet resistance in ischemic stroke patients
- Trial name
- NCT03823274
- Testing
- Aspirin, Clopidogrel
- Where
- South Korea
- Volunteers
- 1,011 people
- Sponsor
- Yuhan Corporation
Amputation, PTSD
Evacuation Time and Tourniquet Use as Risk Factors for PTSD in Combat-Related Amputation
This study aims to evaluate the relationship between evacuation time, tourniquet use, and the development of post-traumatic stress disorder (PTSD) in patients with combat-related amputations.
- Conditions
- Amputation, PTSD, Combat Posttraumatic Stess Disorder, Combat Trauma
- Trial name
- EVAC-PTSD Stud (NCT07502313)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Absenteeism, Sick Leave
WB6Dim-LTSA: Can Workplace Well-Being Scores Predict Collective Absenteeism?
This prospective multicenter cohort study evaluates the predictive value of the Adaptive Load Index (ICA), a composite indicator derived from the WB6Dim well-being instrument, on long-duration sick leave (≥ 30 days) in French…
- Conditions
- Absenteeism, Sick Leave, Workplace Well-Being, Occupational Stress
- Trial name
- WB6Dim-LTSA (NCT07606261)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Clover Link
Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome
Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS
This open-label study investigates the effects of lecithin-based formulations of Curcuma longa (Meriva™) and Boswellia serrata (Casperome™) extracts on post-acute COVID-19 irritable bowel syndrome (PCIBS) and irritable bowel…
- Conditions
- Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome, Abdominal Pain, Dysbiosis
- Trial name
- NCT06423586
- Testing
- Curcuma longa and Boswellia serrata extracts
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Extubation Failure
Validation of an Effort-Based Cough Peak Flow Algorithm to Predict Extubation Outcomes
This study aims to prospectively validate the diagnostic accuracy of an effort-stratified Cough Peak Flow (CPF) decision algorithm for predicting extubation failure, maintaining strict blinding of the clinical team.
- Trial name
- NCT07737483
- Testing
- Observational measurement of Cough Peak Flow and Tidal Volume
- Volunteers
- 150 people
- Sponsor
- Hospital H+ Queretaro
Alzheimer's Disease, Mild Cognitive Impairment
Diagnosis and Monitoring of Disease Progression Using Deep Neuro Signatures
Alzheimer's disease (AD) clinically characterized by the cognitive impairment and lowering of various functional abilities lead to staggering costs and suffering, which are particularly related to the social impacts of caring for…
- Trial name
- DNS (NCT05153941)
- Where
- Greece
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Altoida
Myasthenia Gravis Generalised
Detecting Fatigue From Voice in Generalised Myasthenia Gravis
The goal of this observational study is to learn if computer analysis of voice recordings can detect a type of exhaustion called "central fatigue" in adults with generalised myasthenia gravis.
- Trial name
- NCT07033559
- Volunteers
- 240 people
- Sponsor
- Thymia Limited
Sepsis, Shock
Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS)
Investigation of the feasibility of using near-infrared spectroscopy (NIRS) to monitor microvascular function in critically ill patients.
- Conditions
- Sepsis, Shock, Critical Illness
- Trial name
- MiMICSS (NCT05985525)
- Testing
- Skeletal muscle and cerebral NIRS (research device)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Chronic Respiratory Disease
Tele-rehabilitation in Chronic Respiratory Disease: an Observational Cohort Study
Pulmonary rehabilitation is a program that helps people with lung disease improve their function. It uses exercise, education, and self-management strategies to improve physical ability and quality of life.
- Trial name
- NCT05820776
- Testing
- pulmonary rehabilitation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- West Park Healthcare Centre
COVID-19 Vaccination, Gut Microbiota
Gut Microbiota Profile and Its Impact on Immunity Status in COVID-19 Vaccinated Cohorts
This study aims to examine the association between gut microbiota composition and the magnitude and duration of immune response in subjects who have received different COVID-19 vaccines in Hong Kong and to identify the…
- Trial name
- NCT04980560
- Where
- Hong Kong
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Invasive Fungal Infections
Retrospective Study of Invasive Fungal Infections With Filamentous Fungi in Heart Transplant Patients
Invasive filamentous fungal infections (aspergillosis, scedosporiosis, mucormycosis, fusarium wilt) are common and serious in immunocompromised subjects and particularly organ transplant patients.
- Trial name
- IMI-CART (NCT06498310)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Endophthalmitis
Ozurdex Endophtamitis Cohort, Prognostic Assessment at 12 Months
OZURDEX endophthalmitis is a rare and potentially very serious pathology. Different treatments can be carried out early and change the functional prognosis of the patient.
- Trial name
- NCT06268561
- Testing
- Visual acuity analysis, Intraocular pressure analysis, Analysis of optical coherence tomography (OCT) images
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Effect of Insomnia and Sleep Deprivation in 3rdtrimester
Effect of Clinical Insomnia and Sleep Deprivation on Maternal-fetal Outcome Among Egyptian Females in 3rd Trimester
This prospective observational study aims at investigating whether insomnia or sleep deprivation during the 3rd trimester of pregnancy can be implicated in the occurrence of adverse maternal or fetal outcome.
- Trial name
- NCT04612361
- Testing
- insommnia severity index questionnaire
- Where
- Egypt
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Dr. Osman Hospital
Pulmonary Arterial Hypertension (PAH), Sleep-disordered Breathing (SDB)
PAH-SDB: Sleep-Disordered Breathing and Outcomes in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease characterized by increased pulmonary vascular resistance, right ventricular dysfunction, and clinically important morbidity and mortality.
- Trial name
- PAH-SDB (NCT07852403)
- Testing
- Standardized Overnight Sleep and Cardiorespiratory Monitoring
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Cancer/Squamous Cell Carcinoma of Skin
Comparative Efficacy of Cemiplimab to Historical Standard of Care in France
Primary Objective: -Assess the effectiveness of cemiplimab versus other available systemic therapies in patients up to 2018 or say historical system organ class (SOC) with metastatic or locally advanced cutaneous Squamous Cell…
- Trial name
- TOSCA (NCT05302297)
- Testing
- Cemiplimab
- Where
- France
- Volunteers
- 305 people
- Sponsor
- Sanofi
Closed Reduction, Arthroplasty, Replacement, Hip
Associations Between Time to Reduction and Complications in Patients With Dislocated Total Hip Arthroplasty
The aim of the study is to investigate the impact of time to closed reduction on both patient related and organizational factors.
- Conditions
- Closed Reduction, Arthroplasty, Replacement, Hip, Length of Stay
- Trial name
- NCT07132723
- Testing
- Time in minutes from admission to closed reduction
- Where
- Denmark
- Volunteers
- 3,700 people
- Sponsor
- Nordsjaellands Hospital
Growth Retardation
The Effects of Time Points to Cease Parenteral Nutrition and IGF-1 on Very Low Birth Weight Infants
This study aims to estimate short-term and long-term effects of time points to cease parenteral nutrition on very preterm infants, such as growth; to estimate the role of insulin-like growth factor 1 in the growth.
- Trial name
- NCT06071403
- Testing
- (enteral feeding volume/ total fluid volume)*100%
- Where
- China
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Peking University
Asthma
Monitoring of Patients With Asthma Performed by a Clinical Pharmacist Using a Mobile Application
Asthma is a chronic inflammatory disease that affects the lungs. In Brazil it is responsible for about 4 to 8 deaths per day. Pharmacotherapeutic follow-up programs for people with asthma have a positive impact on treatment…
- Trial name
- NCT05503342
- Testing
- Mobile Application, Asthma control assessment
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Rafael Stelmach
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