Clinical trials: Cohort
Obstructive Sleep Apnea, Sleep Disorder
Validation of Pediatric Sleep Questionnaire on a Swedish Cohort
This study is aimed to validate the questionnaire called Pediatric Sleep Questionnaire on a Swedish cohort of children from 18 months to 15 years old with obstructive sleep disordered breathing.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Sleep Disorders in Children, Obstructive Sleep Apnea of Child
- Trial name
- NCT06367400
- Testing
- Pediatric Sleep Questionnaire
- Where
- Sweden
- Volunteers
- 520 people
- Sponsor
- Uppsala University
Coronavirus Disease 2019
Neurologic Manifestations of COVID-19
This study will determine the neurological profile and predictors of outcomes in patients with COVID-19 disease in the Philippines.
- Trial name
- CORONA (NCT04386083)
- Where
- Philippines
- Volunteers
- 1,342 people
- Sponsor
- University of the Philippines
Idiopathic Retroperitoneal Fibrosis
A Prospective Cohort Study of IRPF in China
This is a cohort study to investigate the disease course and treatment response of patients with idiopathic retroperitoneal fibrosis（IRPF）.
- Trial name
- IRPF (NCT04312854)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy
Birth Cohort Study of China Medical University
The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity
- Trial name
- NCT03561766
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Multiple Sclerosis (MS), Clinically Isolated Syndrome (CIS)
Pregnancy Cohort in Multiple Sclerosis (MS)
Multiple sclerosis (MS) is a common inflammatory demyelinating disorder of the central nervous system frequently affecting females in their reproductive phase of life.
- Trial name
- NCT05010902
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Clear Cell Renal Cell Carcinoma, Cervical Carcinoma
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors
This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX131™ in subjects with relapsed or refractory solid tumors.
- Conditions
- Clear Cell Renal Cell Carcinoma, Cervical Carcinoma, Esophageal Carcinoma, Pancreatic Adenocarcinoma
- Trial name
- NCT05795595
- Testing
- CTX131
- Where
- 7 sites in United States
- Volunteers
- 19 people
- Sponsor
- CRISPR Therapeutics AG
Pulmonary Disease, Chronic Obstructive
Effectiveness of Triple Therapy in COPD
To assess the effectiveness of maintenance treatment of Chronic obstructive pulmonary disease (COPD) with the Long-acting beta2-agonist - long-acting muscarinic antagonists-inhaled corticosteroids (LABA-LAMA-ICS) combination with…
- Trial name
- NCT03724877
- Testing
- Long-acting beta2-agonist-long-acting muscarinic antagonists-inhaled corticosteroids(LABA-LAMA-ICS), Long-acting beta2-agonist-inhaled corticosteroids-long-acting muscarinic antagonists (LABA-LAMA)
- Where
- United Kingdom
- Volunteers
- 8,853 people
- Sponsor
- Boehringer Ingelheim
Hepatocellular Carcinoma, Non-cirrhotic Liver
Liver Transplantation for Hepatocellular Carcinoma Arising in Non-cirrhotic Liver: a Propensity Score-matched Retrospective Cohort Study of Two National Databases
Background: Majority of liver transplantation (LT) recipients for hepatocellular carcinoma (HCC) were concomitant with liver cirrhosis, while few researches focusing on recipients without cirrhosis.
- Trial name
- NCT06364839
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Xiao Xu
Coronary Stenosis
IRIS-BioFreedom Cohort in the IRIS-DES Registry
The objective of this study is to evaluate effectiveness and safety of BIOFREEDOM™ FAMILY stent in the "real world" daily practice as compared with other drug-eluting stents.
- Trial name
- IRISBioFreedom (NCT03190057)
- Testing
- BIOFREEDOM™ FAMILY stent
- Where
- 8 sites in South Korea
- Volunteers
- 218 people
- Sponsor
- Seung-Jung Park
Acute Coronary Syndrome
Prognosis of Treated Acute Coronary Syndrome Patients: a Multicenter Study
The MPCS-ACS Study (Multicenter Prospective Cohort Study on Acute Coronary Syndrome) is a comprehensive, forward-looking research project designed to evaluate the prognostic outcomes of patients diagnosed with acute coronary…
- Trial name
- MPCS-ACS (NCT05164601)
- Testing
- No Intervention - Observational Only
- Where
- 2 sites in China
- Volunteers
- 22,500 people
- Sponsor
- Xiang Xie
Pregnancy
Hemodynamic Changes During Normal Pregnancy
Prospective, observational study of the changes in hemodynamic variables such as blood pressure, cardiac output, systemic vascular resistance, and of changes in respiratory variables such as vital capacity, and functional…
- Trial name
- NCT00682201
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Heart Failure With Preserved Ejection Fraction, Malnutrition
A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly CAD Patients With HFpEFand Compare CONUT With Other Objective Nutritional Indices.
HF is an advanced or terminal stage of various heart diseases, with high rehospitalization and mortality rates. In HF patients, undernutrition is not uncommon and represents one of the most significant determinants of poor…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Malnutrition, Aged, Prognosis
- Trial name
- NCT05586828
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Beijing Tongren Hospital
Malignant Melanoma, Squamous Cell Carcinoma of Skin
A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)
Primary Objective: -To determine the antitumor activity of SAR444245 in combination with cemiplimab. Secondary Objectives: To determine the recommended phase 2 dose and to assess the safety profile of SAR444245 when combined with…
- Trial name
- NCT04913220
- Testing
- THOR-707, Cemiplimab
- Where
- 24 sites in United States, Australia and 5 more
- Volunteers
- 46 people
- Sponsor
- Sanofi
Acute Lymphoblastic Leukemia, Pediatric
Vaccine Immune Recovery After Leukemia
This observational study aims to assess recovery of the immune system and immunity to vaccine-preventable diseases in children, adolescents, and young adults who recently completed treatment for acute lymphoblastic leukemia…
- Trial name
- VIRAL (NCT05622682)
- Testing
- Observational only: Serology and flow cytometry for ALL cohort participants, Observational only: Infection rates
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Pseudoxanthoma Elasticum
Phenotypic Expressions in a French Pseudoxanthoma-Elasticum Cohort
The cohort is intended to study the phenotypic expressions of the pseudoxanthoma elasticum (PXE) disease in various tissues (eye, skin, arteries, etc).
- Trial name
- NCT01446380
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Angers
Stroke, Atrial Fibrillation
HEart and BRain Interfaces in Acute Ischemic Stroke
The primary aim of this prospective observational study is to investigate whether an enhanced diagnostic MRI work-up (including cardiac MRI, angiography of the aortic arch and the brain-supplying arteries) combined with an…
- Trial name
- HEBRAS (NCT02142413)
- Where
- Germany
- Volunteers
- 368 people
- Sponsor
- Charite University, Berlin, Germany
Cubital Tunnel Syndrome
Health-Related Quality of Life in Cases of Cubital Tunnel Syndrome
This study aims to determine the Health Related Quality of life (HRQOL) (the physical, mental, emotional and social functioning) of patients with cubital tunnel syndrome following anterior intramuscular transposition, after one…
- Trial name
- NCT02995382
- Testing
- Anterior Intramuscular Transposition
- Sponsor
- McMaster University
Bariatric Surgery
Study of Bariatric Surgery
The aim of this cohort study is to collect prospectively clinical data on all the patients admitted in the investigators department for bariatric surgery or for any complication of a bariatric procedure.
- Trial name
- BARIASURG (NCT02857179)
- Testing
- bariatric surgery
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Hospices Civils de Lyon
Pancreatic Cancer, Metastatic Castration-resistant Prostate Cancer
Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
Study of NGM120 in subjects with advanced solid tumors and pancreatic cancer (Part 1 and 2) and metastatic castration resistant prostate cancer (Part 3).
- Conditions
- Pancreatic Cancer, Metastatic Castration-resistant Prostate Cancer, Bladder Cancer, Melanoma
- Trial name
- NCT04068896
- Testing
- NGM120 30mg, NGM120 100mg, NGM120 30mg with Gemcitabine and Abraxane
- Where
- 20 sites in United States
- Volunteers
- 89 people
- Sponsor
- NGM Biopharmaceuticals, Inc
Safety
Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4
A phase one study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. Cohorts of healthy adults (female and male) will participate in: single dose escalation study of increasing doses of MRX-4…
- Trial name
- NCT03033342
- Testing
- Oral single doses of MRX-4, Oral multiple doses of MRX-4, MRX-4 co-administered with omeprazole
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- MicuRx
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