Clinical trials: Cohort
Problem With Growth of an Infant
Cohort Construction for Preterm Infants With Growth Retardation and Its Influencing Factors
In this cohort, prospective clinical cohort study was used to establish a follow-up cohort of preterm infants with different gestational ages.
- Trial name
- NCT04817878
- Testing
- Developmental assessment
- Where
- China
- Volunteers
- 2,400 people
- Sponsor
- Peking University Third Hospital
Thoracic Anesthesia, One Lung Ventillation (OLV)
Association Between One Lung Ventilation and Myocardial Injury Markers (Troponin T and I) in Thoracic Surgical Procedures (OLVTIS)
This prospective single-group cohort study aims to investigate the association between the One-Lung Ventilation (OLV) technique and myocardial injury, as measured by postoperative Troponin T and Troponin I levels, in patients…
- Trial name
- OLVTIS (NCT07302243)
- Where
- Indonesia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Lung-transplant Recipients, Antibiotic Prophylaxis
Antibiotic Prophylaxis in Lung-Transplant Recipients
Retrospective, monocentric observational pharmacological cohort study including all adult patients who underwent lung transplantation at IRCCS Azienda Ospedaliero-Universitaria di Bologna from 1st January 2002 to 31st August 2023.
- Trial name
- PRO-LUNG (NCT06760143)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Rectal Neoplasms
Transanal Total Mesorectal Excision Versus Laparoscopic TME for Rectal Cancer
To investigates the feasibility, practicability, safety and subjective as well as functional outcome of transanal minimal invasive surgery toal mesentery excision for rectal cancer.
- Trial name
- NCT02252250
- Testing
- conventional laparoscopic total mesentery excision, transanal hybrid-laparoscopic total mesentery excision
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Third Military Medical University
Hepatic Encephalopathy, Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Coil-Assisted Small-Diameter Covered-Stent Shunt Reduction for Refractory Hepatic Encephalopathy After TIPS
Refractory hepatic encephalopathy (RHE) after transjugular intrahepatic portosystemic shunt (TIPS) is a serious complication that can markedly impair quality of life and worsen prognosis.
- Conditions
- Hepatic Encephalopathy, Transjugular Intrahepatic Portosystemic Shunt (TIPS), Portal Hypertension, Liver Cirrhosis
- Trial name
- NCT07799948
- Testing
- Coil-assisted Small-diameter Stent Shunt reduction
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Air Force Military Medical University, China
Actinic Keratoses
Implementation of Actinic Keratosis Guideline Among General Practitioners.
This study investigates 5-fluorouracil cream prescription trends by general practitioners for the treatment of field changes of actinic keratosis over the years 2016-2021.
- Trial name
- NCT05976048
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Maastricht University Medical Center
Peri-implant Health
The Socket Shield Technique, a Prospective Cohort Study of 20 Patients
23 implants with socket shield were followed for 18 months. buccal bone thickness and survival rates registered.
- Trial name
- NCT05902715
- Testing
- oral implant placement with socket shield technique
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Tick-Borne Diseases
SWEtick - a Prospective Multicenter Study of Tick-borne Diseases in Sweden
The purpose of the SWEtick project is to increase the knowledge of the various clinical presentations of emerging tick-borne diseases (eTBD), to assess their importance for human health, to develop and validate laboratory methods…
- Trial name
- SWEtick (NCT06781008)
- Where
- 12 sites in Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Region Jönköping County
Hypertension in Pregnancy
Understanding Blood Pressure Changes After Birth
Research Question How does maternal blood pressure respond in the postpartum period for women who had a hypertensive disorder in pregnancy? Aim To evaluate the recovery of maternal blood pressure after a pregnancy affected by new…
- Trial name
- NCT05137808
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- St George's, University of London
Squamous Cell Carcinoma of the Head and Neck
SUPREME-HN A Retrospective Cohort Study of PD-L1 in Recurrent and Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN)
This is a retrospective international, multi-center, non-interventional cohort study based on use of data derived from established medical records and secondary analysis of archival tumor samples.
- Trial name
- SUPREME-HN (NCT02543476)
- Where
- 18 sites in United States, Germany and 5 more
- Volunteers
- 412 people
- Sponsor
- AstraZeneca
Epileptic Encephalopathy
Prospective Cohort Study on the Efficacy of Vagus Nerve Stimulation for Children and Adolescents With Epilepsy(PVNS-CAE)
Prospective cohort study on the long-term effectiveness and safety of PINS vagus nerve stimulators for children and adolescent with refractory epilepsy.
- Trial name
- NCT02603991
- Testing
- PINS Vagus Nerve Stimulator, Levetiracetam
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Refractory Solid Tumors, Pancreatic Adenocarcinoma
A Phase I/Expansion Study of Dasatinib
The purpose of this study is to find the highest dose of the drugs gemcitabine and dasatinib that can be given for the treatment of pancreatic cancer. Gemcitabine (also called Gemzar™)is a drug that is given intravenously.
- Trial name
- Gem/Dsat (NCT00598091)
- Testing
- gemcitabine, dasatinib
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Cardiovascular Diseases, Fracture
Prevalence and Risk Factors for Common Diseases
By using national databases in Sweden the aim of the present project is to: 1. Investigate if the incidence of our most common diseases, such as fracture and cardiovascular disease, has changed from 1970-2017 2.
- Conditions
- Cardiovascular Diseases, Fracture, Cancer
- Trial name
- NCT04091035
- Testing
- To describe the incidence of disease and evaluate risk factors
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Anna Nordström
HR+/HER2- Breast Cancer, Breast Neoplasms
Pre-Treatment DCE-MRI AI Models Predict Neoadjuvant Chemotherapy Response in HR+/HER2- Breast Cancer
This study is a multicenter, prospective, observational cohort study to evaluate the predictive performance of pre-treatment DCE-MRI-based artificial intelligence (AI) models for neoadjuvant chemotherapy benefit in HR+/HER2…
- Trial name
- NCT07702708
- Testing
- Pre-treatment DCE-MRI-based AI model
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Fujian Cancer Hospital
Tuberculosis
Development of a Clinical-epidemiological Score Predictive of Tuberculosis.
Despite being a curable and preventable disease, tuberculosis still represents a major global health problem. It is estimated that 10.8 million people contracted tuberculosis in 2023, with an incidence of 134 per 100,000…
- Trial name
- SCORE-TB (NCT07485868)
- Testing
- Development and validation of a clinical-epidemiological predictive score for the diagnosis of pulmonary tuberculosis
- Volunteers
- 686 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Liver Cirrhosis, Hepatocellular Carcinoma
Abbreviated MRI Using Gadoxetic Acid Versus Ultrasonography for Surveillance of Early-stage HCC in Patients at High Risk
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related deaths worldwide. The incidence of HCC has been rapidly rising worldwide over the last two decades.
- Trial name
- NCT06312826
- Testing
- Abdominal US, AMRI
- Where
- South Korea
- Volunteers
- 806 people
- Sponsor
- Asan Medical Center
Bronchopulmonary Dysplasia, Pulmonary Hypertension
Pulmonary Hypertension in Extremely Preterm Infants
Extremely preterm infants are at risk for developing bronchopulmonary dysplasia (BPD) and associated chronic pulmonary hypertension (PH), a consequence of altered pulmonary vasculature.
- Conditions
- Bronchopulmonary Dysplasia, Pulmonary Hypertension, Premature Birth
- Trial name
- PiEP (NCT05136235)
- Testing
- Echocardiography, NT-proBNP
- Volunteers
- 350 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cesarean Delivery
Anesthesia and Neonatal Outcomes After Cesarean Delivery
This retrospective observational study examines the association between the type of anesthesia used during cesarean delivery and early neonatal outcomes.
- Trial name
- NCT07893808
- Testing
- General Anesthesia (GA), Neuraxial Anesthesia (NA)
- Where
- Turkey (Türkiye)
- Volunteers
- 21,926 people
- Sponsor
- Serra Topal
Patellofemoral Pain Syndrome, Knee Pain
5 Year Follow-up of Adolescents With Knee Pain
The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.
- Trial name
- NCT02873143
- Testing
- No intervention
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Solid Tumor, Adult
Prospective Cohort With Clinic-biologic Database of Patients Treated by Immunotherapy
ImmuCCo-1905 is a monocentric interventional study on patients treated by immunotherapy, which consist in establishment of a prospective clinic-biologic database over 5 years, associated with a biobank.
- Trial name
- ImmuCCo (NCT05223608)
- Testing
- ImmuCCo Cohort
- Where
- France
- Volunteers
- 651 people
- Sponsor
- Centre Oscar Lambret
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