Clinical trials: Cohort
Maternal; Procedure
Total Placenta Previa Associated With the Placenta Accreta Spectrum.
To assess the reliability of placental magnetic resonance imaging measurements in predicting peripartum hysterectomy and neonatal outcomes in patients with total placenta previa.
- Trial name
- PAS (NCT06219564)
- Testing
- Peripartum total abdominal hysterectomy (p-TAH), Cesarean Section (C/S), Neonatal mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Pathological or "at Risk" Gambling
Transversal Multiaxial Evaluation and 5-year Follow-up of a Cohort of French Gamblers (JEU)
This study is divided into two stages. The first stage is a transversal study and corresponds to the recruitment of participants, which will last about two years.
- Trial name
- NCT01207674
- Testing
- Summons of patients and filling questionnaire
- Where
- 7 sites in France
- Volunteers
- 641 people
- Sponsor
- Nantes University Hospital
Obstructive Sleep Apnea
Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea With Complete Concentric Collapse
This study examines how hypoglossal nerve stimulation affects breathing and sleep apnea in adults whose airway closes from all sides at the soft palate during sleep, a pattern called complete concentric collapse.
- Trial name
- NCT07898618
- Testing
- Inspire Hypoglossal Nerve Stimulation System
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Liver Cirrhosis, Hepatocellular Carcinoma
Boramae Hospital Liver Cirrhosis Patient Cohort Study
Liver cirrhosis represents a worldwide health problem and is a major cause of mortality. Cirrhosis is the common end for chronic alcohol abuse and hepatitis C and B virus infections.
- Trial name
- NCT01943318
- Testing
- Liver biopsy, Hepatic venous pressure gradient (HVPG) measurement
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Boramae Hospital
Cardiovascular Risk Factor, Burnout
Impact of Burnout on Cardiovascular and Immune Biomarkers in Healthcare Professionals - Covid-19 Pandemic in Abu Dhabi
The main objective of our project is to investigate the evolution of psychosocial, cardiovascular and immune markers in healthcare with different levels of exposure to the COVID-19 pandemic.
- Conditions
- Cardiovascular Risk Factor, Burnout, Immune Deficiency
- Trial name
- NCT04422418
- Where
- 4 sites in United Arab Emirates
- Volunteers
- 200 people
- Sponsor
- Khalifa University for Science and Technology
Regional Anesthesia, Vascular Grafting, Vascular Patency
Anesthesia Technique and Lower Limb Revascularization Patency
The role of regional anesthesia in lower extremity revascularization procedures on reducing graft failure and need for reoperation remains unclear.
- Trial name
- NCT04730310
- Testing
- NSQIP Lower Extremity Open (LEO) procedure-targeted dataset (i.e. undergoing Lower extremity open revascularization) from 2014-2019
- Where
- Canada
- Volunteers
- 8,893 people
- Sponsor
- University of British Columbia
Lactation, Bone Diseases, Endocrine
African-American Bone Metabolism and Lactation Study
The primary aim of this study is to obtain measures of amino-terminal telopeptides of procollagen 1 (P1NP), a marker of bone formation, in lactating and non-lactating post-partum African-American women both at 6-8 and at 12-14…
- Trial name
- NCT00785824
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hip Fracture, Perioperative Myocardial Injury
Nerve Block and Perioperative Myocardial Injury in Elderly Hip Fracture
This single-center, retrospective cohort study evaluates whether a single preoperative peripheral nerve block can reduce the risk of perioperative myocardial injury in elderly patients undergoing delayed hip fracture surgery…
- Conditions
- Hip Fracture, Perioperative Myocardial Injury, Myocardial Injury After Noncardiac Surgery
- Trial name
- PNB-CARD (NCT07751146)
- Testing
- PNB, Non-PNB
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Inflammatory Bowel Disease
Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study
This is a Phase 1, open-label, 2-cohort, food-effect, DDI, and formulation bridging study.
- Trial name
- NCT03555617
- Testing
- TD-1473, Itraconazole
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Acetabular Dysplasia
Targeted Exercise and Changes in Femoroacetabular Impingement in Symptomatic Patients With Acetabular Retroversion
The objective of this study is to investigate the effectiveness of an 8-week home-based targeted training intervention aiming at reducing FAI related pain, anterior pelvic tilt and improve hip joint function in a cohort of 40…
- Trial name
- TILT-FAI (NCT03578562)
- Testing
- Targeted training intervention
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Southern Denmark
Lassa Fever, Lassa Virus Infection
Lassa Fever Clinical Course and Prognostic Factors in Nigeria
The investigators propose to conduct a nationwide (Nigeria), prospective, non-interventional cohort study describing the clinical course, biological characteristics, case management and outcomes in patients hospitalized for a…
- Conditions
- Lassa Fever, Lassa Virus Infection, Pregnancy Complications, Acute Kidney Injury
- Trial name
- LASCOPE (NCT03655561)
- Testing
- Non interventional research
- Where
- 2 sites in Nigeria
- Volunteers
- 1,100 people
- Sponsor
- Alliance for International Medical Action
Metabolic Associated Fatty Liver Disease
A Prospective Cohort Study of Metabolic Associated Fatty Liver Disease in China
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new concept proposed in 2020. Unlike non-alcoholic fatter liver disease (NAFLD), the diagnosis of MAFLD requires the presence any of the following 3 metabolic…
- Trial name
- NCT04573283
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Sleep
Effect of Asynchronies on Sleep Disruption During Mechanical Ventilation
Mechanically ventilated (MV) patients in the Intensive Care Unit (ICU) are highly susceptible to sleep disruption. Several studies in the last 15 years have demonstrated an extremely poor sleep quality and abnormal sleep pattern…
- Trial name
- SleepUCI (NCT05847374)
- Testing
- Polysomnography
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Healthy
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a New Formulation of Oritavancin in Healthy Volunteers
The protocol describes a double-blind study to evaluate the Pharmacokinetics and safety of a new formulation of oritavancin by adjusting infusion time, concentration and reconstitution/administration solutions, of a single 1200…
- Trial name
- NCT02471690
- Testing
- Oritavancin, Dextrose
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- The Medicines Company
Colon Cancer, Rectum Cancer
Evaluating Factors Affecting Survival in Colon and Rectum Cancer
Colorectal cancers are frequent among cancers of the gastrointestinal system. Whether there are any differences between survival in rectum and colon cancer patients is controversial.
- Trial name
- NCT05388513
- Testing
- Surgical Resection
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Pediatric Cancer, Cancer
UNC Childhood, Adolescent, and Young Adult Cancer Cohort
Purpose: This study aims to create a registry of childhood, adolescent, and young adult patients with cancer (<40 years-old at cancer diagnosis), entitled the 'UNC Childhood, Adolescent, and Young Adult Cancer Cohort'…
- Conditions
- Pediatric Cancer, Cancer, Cancer Metastatic, Survivorship
- Trial name
- UNC-CAYACC (NCT05096923)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Transplantation
Vaccines Immunogenicity in Renal, Hepatic, Cardiac or Pulmonary Transplanted Children
Thanks to improved surgical techniques, postoperative management and immunosuppressive therapies, an increasing number of children benefit from renal, hepatic, cardiac and pulmonary transplantation.
- Trial name
- COVAGREF (NCT03180359)
- Testing
- Recommended vaccine scheme according to French Vaccine Schedule 2015
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hospices Civils de Lyon
Asthma
Longitudinal Assessment of Children With Severe Asthma and Severe Pre-school Wheeze
Cross-sectional study to characterize cohorts of children with asthma and healthy controls in terms of clinical features, physiological measurements and non-invasive measurement of biomarkers and develop phenotype handprints for…
- Trial name
- NCT01982162
- Volunteers
- 300 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Netherton Syndrome
A Study to Assess the Safety and Pharmacokinetics of Multiple Ascending Subcutaneous Doses of DS-2325a in Healthy Subjects
Netherton syndrome (NS) is a rare autosomal recessive disease and no systemic treatment or standard of care currently exists for patients with NS.
- Trial name
- NCT05583669
- Testing
- DS-2325a
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Breast Cancer Metastatic, Breast Cancer Survival
21-gene in Elder Breast Cancer Patients With Lymph Node Metastasis
This study is a single-center, bidirectional cohort study. It aims to include 35 elderly (≥65 years old) Luminal A type breast cancer patients with axillary lymph node metastasis after surgery as the research subjects.
- Trial name
- QiluElderHope (NCT06891651)
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Qilu Hospital of Shandong University
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