Clinical trials: Coiling Therapy
Cerebral Aneurysm
Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients
Goal directed therapy (GDT) is a technique, which employs a non-invasive cardiac output monitoring (NICOM) device to guide management of circulating blood volume and blood pressure during procedures.
- Trial name
- NCT02507999
- Testing
- Flotrac
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Intracranial Aneurysm, Subarachnoid Hemorrhage
HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study
HYBRID study is prospective randomized open label controlled multi center trial, to compare Hydrocoil and bare platinum coil for recanalization after endovascular treatment of intracranial aneurysms.
- Trial name
- HYBRID (NCT01516658)
- Testing
- Hydrogel coil, Bare platinum coil
- Where
- 2 sites in Japan
- Volunteers
- 431 people
- Sponsor
- Kobe City General Hospital
Major Depression
Evaluation of Deep Transcranial Magnetic Stimulation (TMS) H-Coil in the Treatment of Major Depression
This study is evaluating the safety and feasibility of the novel deep TMS H-coil designs in the treatment of resistant major depression in an open study using two different H-coil designs.
- Trial name
- NCT00445237
- Testing
- H1 and H2 deep TMS coils
- Where
- Israel
- Sponsor
- Shalvata Mental Health Center
Emphysema
Endoscopic Lung Volume Reduction Coil Treatment in Patients With Chronic Hypercapnic Respiratory Failure
Endoscopic lung volume reduction coil treatment is a treatment option for selected patients with severe emphysema. In the advanced stages, emphysema may lead to chronic hypercapnic respiratory failure.
- Trial name
- NCT02996149
- Testing
- Endoscopic lung volume reduction coil treatment
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Strictures Due to Crohn's Disease
A Phase 2, Placebo-Controlled Study of Oral RXC008 for Crohn's Strictures
Crohn's disease (CD) is chronic inflammatory bowel disease where any part of the Gastrointestinal (GI) tract can become inflamed and develop fibrotic strictures.
- Trial name
- ROCKETEER (NCT07832435)
- Testing
- High Dose, Low Dose
- Volunteers
- 180 people
- Sponsor
- Redx Pharma Ltd
Bipolar Depression
Treatment of Bipolar Depression With H1-Coil Deep Brain rTMS: Clinical-Cognitive and Safety Evaluation
The treatment of bipolar disorders is always a challenge in daily practice. Mood stabilizers are partially effective in the treatment of depressive phase of the illness, although there are some reports relating to the…
- Trial name
- rTMSH1Coil (NCT01962350)
- Testing
- Deep Brain Transcranial Magnetic Stimulation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Intracranial Aneurysms
MAPS Trial: Matrix And Platinum Science
Primary Objectives: To establish Target Aneurysm Recurrence (TAR) rates for Matrix 2® and GDC® Coils used for the treatment of intracranial saccular aneurysms.
- Trial name
- MAPS (NCT00396981)
- Testing
- Matrix 2® coils for endovascular aneurysm occlusion, GDC® coils for endovascular aneurysm occlusion
- Where
- 43 sites in United States, Australia and 9 more
- Volunteers
- 626 people
- Sponsor
- Stryker Neurovascular
Glue; Dependence
SAFETY AND EFFICACY OF ENDOSCOPIC CONVENTIONAL CYANOACRYLATE GLUE VS EUS-GUIDED COIL PLUS CYANOACRYLATE TECHNIQUE IN THE TREATMENT OF GASTRIC VARICES: A RANDOMIZED CONTROLLED TRIAL
To compare safety and efficacy of Endoscopic conventional technique (cyanoacrylate alone) to the EUS-guided injection technique (coil and cyanoacrylate) in the treatment of gastric varices.
- Trial name
- GLUE (NCT05038319)
- Testing
- EUS
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Parkinson Disease, Freezing of Gait
Efficacy of Deep-coil Based Repetitive Transcranial Magnetic Stimulation in the Treatment of Parkinson's Disease With Freezing of Gait and Its Neural Regulation Mechanism Study of Resting-state Cerebral Blood Flow
The protocol for repetitive transcranial magnetic stimulation (rTMS) in treating Parkinson's disease (PD) with freezing of gait (FOG) has not yet established an internationally unified standard, and the heterogeneity of treatment…
- Trial name
- NCT06888778
- Testing
- repetitive transcranial magnetic stimulation (rTMS), Non-stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Emphysema
Changes in Lung Physiology and Cardiac Performance in Patients With Emphysema Post Bilateral RePneu Coil Treatment
The objective of this post-marketing study is to advance the understanding of the mechanism of action of the CE marked RePneu Coil by observing changes in lung physiology and cardiac performance in patients with emphysema treated…
- Trial name
- NCT02499380
- Testing
- PneumRx Coil System
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Boston Scientific Corporation
Gastric Varices
Gastric Varices Treatment: Coil + Cyanoacrylate Versus Cyanoacrylate
The purpose of the spring is to maintain the cyanoacrylate polymer of the gastric varix, forming a conglomerate spring-cyanoacrylate, and thus preventing their migration to the adhesive embolism.
- Trial name
- NCT02115061
- Testing
- Treatment: coil + cyanoacrylate, Treatment: cyanoacrylate
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo General Hospital
Major Depressive Disorder
Pilot Study in Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depression
The purpose of this study is to assess the efficacy of a Deep Shaped-Field repetitive transcranial magnetic stimulation (DSF-rTMS) system in the treatment of depression.
- Trial name
- NCT01431001
- Testing
- Cervel Neurotech Deep Shaped-Field repetitive transcranial magnetic stimulator (DSF-rTMS)
- Where
- 4 sites in United States, Australia
- Volunteers
- 40 people
- Sponsor
- Cervel Neurotech, Inc.
Intracranial Aneurysm
LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy
In this study, patients with large anterior circulation IAs with neck and fundus morphologies amenable to either traditional endovascular treatments using coils or reconstruction with the flow diversion will be randomly assigned…
- Trial name
- LARGE (NCT01762137)
- Testing
- Flow Diversion, Coiling
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Medical University of South Carolina
Emphysema
Lung Volume Reduction Coil Treatment in Emphysema.
BACKGROUND: Medical therapeutic options for the treatment of emphysema remain limited. Lung volume reduction surgery is infrequently used because of its high morbi-mortality.
- Trial name
- STICREVOLENS (NCT01822795)
- Testing
- Lung volume reduction coïl treatment, Regular medical treatment
- Where
- 9 sites in France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Data Collection for Facilitation of Machine Learning Algorithm for Personalized Treatment
Combining H1-Coil Deep Transcranial Magnetic Stimulation (dTMS) and App-guided CBT in Subjects With Major Depression Disorder (MDD)
A naturalistic study design, in which dTMS patients will be randomized to get a free add-on CBT treatment. The dTMS procedure will include treatment as usual, and participants will use the app from post randomization…
- Trial name
- NCT04455646
- Testing
- CBT-based, mobile-delivered, intervention platform
- Where
- 22 sites in United States
- Volunteers
- 540 people
- Sponsor
- Brainsway
Tourette's Syndrome, Obsessive Compulsive Disorder
Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for the Treatment of Tourette Syndrome
This is an open study.approximately 20 patients diagnosed with tourette's syndrome and under pharmAcological or psychotherapy treatments will participate.patients will be recruited from Schneider hospital and all his extensions.
- Trial name
- NCT00965211
- Testing
- HBDL-coil Repetitive Deep Transcranial magnetic stimulation (rdTMS)
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Shalvata Mental Health Center
Post Traumatic Stress Disorder
Deep Transcranial Magnetic Stimulation (TMS)- Treatment for Post Traumatic Stress Disorder
Evaluation of the novel deep TMS H-Coil designs as a treatment measure in post traumatic stress disorder (PTSD). Comparing real to sham treatment.
- Trial name
- NCT00517400
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Pelvic Congestion Syndrome
Fibered Platinum Coils vs Vascular Plugs in Pelvic Varices Embolization for the Treatment of Pelvic Congestion Syndrome
This prospective randomized study compares the safety and efficacy of two different embolizing agents for the treatment of pelvic congestion syndrome: fibered platinum coils and vascular plugs.
- Trial name
- NCT02796092
- Testing
- Fibered platinum coils, Vascular plugs
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Group of Research in Minimally Invasive Techniques
Intracranial Aneurysm
pCONUS2 Treatment of Wide Neck Intracranial Aneurysms 2
To assess safety and efficacy of pCONUS2 for the treatment of wide neck bifurcation aneurysms.
- Trial name
- pToWin2 (NCT03273478)
- Testing
- Endovascular treatment of bifurcation aneurysm with pCONUS2
- Volunteers
- 100 people
- Sponsor
- Phenox GmbH
Emphysema
Evaluation of the PneumRx Lung Volume Reduction Coil to Treat Emphysema
The objective of this study is to demonstrate the safety of the PneumRx Lung Volume Reduction Coil (LVRC) in a population of patients with emphysema. The PneumRx, Inc.
- Trial name
- NCT01220908
- Testing
- Lung Volume Reduction Coil (LVRC), Coils
- Where
- 5 sites in Germany, Netherlands
- Volunteers
- 36 people
- Sponsor
- Boston Scientific Corporation