Clinical trials: Coin Lesion, Pulmonary
Peripheral Pulmonary Lesion, Lung Nodule, Solitary
Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT Using Integrated Intraprocedural Imaging
RELIANT 2 is a pragmatic randomized controlled trial. The goal of this study is to compare the diagnostic yield of robotic assisted bronchoscopy with integrated cone beam computed tomography to that of electromagnetic navigation…
- Trial name
- RELIANT 2 (NCT06654271)
- Testing
- Robotic assisted bronchoscopy (RAB), Electromagnetic navigation bronchoscopy (ENB)
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Nodule, Solitary, Lung Cancer
A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENB
Multi-center randomized controlled study designed to compare the diagnostic yield of ION™ Endoluminal System with electromagnetic navigation bronchoscopy in patients undergoing transbronchial sampling procedure of peripheral…
- Trial name
- ARTICULAtE (NCT06308120)
- Testing
- Ion Endoluminal System, superDimension Navigation System and Accessories
- Where
- 3 sites in China
- Volunteers
- 354 people
- Sponsor
- Intuitive Surgical
Lung Cancer, Lung Cancer Metastatic
Needlescopic-assisted Uniportal vs Uniportal VATS
The investigators' study aims is to evaluate the safety and efficacy of uniportal VATS under assistance of needlescopic instruments through additional 2-3 mm ports compared to conventional uniportal VATS in patients with lung…
- Conditions
- Lung Cancer, Lung Cancer Metastatic, Bullous Disease Lung, Nodule Solitary Pulmonary
- Trial name
- UNeed (NCT03439696)
- Testing
- Thoracoscopic surgery
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- IRB of NTUH Hsin-Chu Branch
Moderate Persistent Asthma, Severe Persistent Asthma
Expressions of TRPV1 in Airway of Asthmatics
The purpose of this study is to measure the density of a temperature-sensitive protein, named TRPV1, in the airway mucosa tissue of both non-asthmatic and moderate to severe persistent asthmatic patients.
- Conditions
- Moderate Persistent Asthma, Severe Persistent Asthma, Nodule Solitary Pulmonary, Pulmonary Atelectasis
- Trial name
- TRPV1 (NCT02952066)
- Testing
- Bronchial biopsy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lu Yuan Lee
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- NCT01958931
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Fresh Medical Laboratories
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Pulmonary Nodule, Solitary, Lung Cancer
Pulmonary Nodule Cohort
The aim of this study is to identify the clinical features of pulmonary nodules and establish a cohort to identify biomarkers for lung cancer.
- Trial name
- liquidNodule (NCT04049422)
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Hospital
Lung Cancer, Pulmonary Nodule, Solitary
Prospective Post-market Data Collection for Ion Endoluminal System to Understand CT to Body Divergence
The goal of this study is to collect post-market data for the Ion Endoluminal System to understand CT to body divergence.
- Trial name
- NCT04735341
- Testing
- Ion Endoluminal System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Intuitive Surgical
Lung Cancer (Diagnosis), Nodule, Solitary Pulmonary
Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule Evaluation
The goal of the NIMBLE study is to evaluate blood-based biomarkers for lung cancer risk prediction in patients referred with a lung nodule.
- Trial name
- NIMBLE (NCT07623473)
- Testing
- Blood tests
- Where
- Denmark
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung China Test in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung China Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- ProLung (NCT02726633)
- Where
- 3 sites in China
- Volunteers
- 500 people
- Sponsor
- Chinese Alliance Against Lung Cancer
Pulmonary Nodules, Solitary
Virtual Bronchoscopic Navigation to Increase Diagnostic Yield in Patients With Pulmonary Nodules
Background Transthoracic computed tomography (CT)-guided procedures are the current gold Standard for obtaining diagnostic biopsies of solitary pulmonary nodules (SPN) in the peripheral lung.
- Trial name
- NAVIGATOR (NCT05383105)
- Testing
- Virtual bronchoscopic navigation
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- University Medical Center Groningen
Solitary Pulmonary Nodule, Bronchial Neoplasms
ThoHSpEkt Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With Free-hand SPECT
Title ThoHSpEkt Study Design Pilot Study concerning the technical operative methods and a phase II study concerning the radiopharmaceutical (therapeutic-explorative study with an approved drug in a new indication) Location…
- Trial name
- ThoHSpEkt (NCT02050724)
- Testing
- Radioactive labelling of pulmonary nodules, CT guided radioactive labelling, Electromagnetic guided bronchoscopic radioactive labelling
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Cantonal Hospital of St. Gallen
Lung Cancer
Ultrathin Bronchoscopy for Solitary Pulmonary Nodules
The evaluation of solitary pulmonary nodules (SPN) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis is endemic.
- Trial name
- Babyscope (NCT02490059)
- Testing
- bronchoscopy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Nodule Solitary Pulmonary, Non-small Cell Lung Cancer
Biomarkers for Risk Stratification in Lung Cancer
This is a prospective observational study that will follow patients who undergo lung cancer screening at the San Francisco VA Medical Center, University of California, San Francisco (UCSF) Medical Center, and the San Francisco…
- Trial name
- NCT03774758
- Testing
- Guardant Health ct-DNA LUNAR assay
- Where
- 3 sites in United States
- Volunteers
- 1,440 people
- Sponsor
- University of California, San Francisco
Solitary Pulmonary Nodule, Biopsy, Fine-Needle
iNod System Human Feasibility Assessment
The purpose of this study is to demonstrate feasibility to access, visualize, and obtain specimens adequate for cytology of lung lesions in subjects with suspected lung cancer when using the iNod System.
- Trial name
- iNod (NCT02832284)
- Testing
- iNod System
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Boston Scientific Corporation
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
iNod™ Ultrasound-Guided Needle Biopsy System Study
The purpose of this study is to collect information on the iNod™ System's safety and ability to see the iNod™ biopsy needle in real-time in endobronchial lesions, peripheral lung nodules, or lung masses.
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Biopsy, Fine-Needle
- Trial name
- NCT05804435
- Testing
- iNod™ System
- Sponsor
- Boston Scientific Corporation
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Virtual Management of Lung Nodules
This is a study to determine how a virtual model for the management of lung nodules compares to a face-to-face clinic for patient satisfaction, quality of life and cost.
- Trial name
- NCT04892524
- Testing
- Virtual multidisciplinary review
- Where
- Australia
- Volunteers
- 55 people
- Sponsor
- Southern Adelaide Local Health Network