Clinical trials: Cold
Otitis Media
Effect of Simethicone on Eustachian Tube Dysfunction
This study is designed to measure the effects of a chewable Simethicone tablet taken by mouth on middle-ear pressure in adults with a common cold and evidence of abnormal middle-ear pressure.
- Trial name
- NCT01312038
- Testing
- Simethicone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Chronic Wounds, Venous Leg Ulcer (VLU)
Evaluation of Cold Plasma in Chronic Wound Healing
The goal of this clinical trial is to evaluate the effectiveness of cold atmospheric plasma treatment in promoting the healing of chronic wounds in adult participants suffering from chronic wounds.
- Conditions
- Chronic Wounds, Venous Leg Ulcer (VLU), Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
- Trial name
- PLASANAGENESIS (NCT06964048)
- Testing
- Cold Atmospheric Plasma treatment
- Volunteers
- 66 people
- Sponsor
- Plasana Medical
Lateral Epicondylitis
Cold Application in Lateral Epicondylitis
Purpose: The purpose of this study was to investigate which cold application is more effective to regulate skin temperature in patients with lateral epicondylitis.
- Trial name
- NCT04536948
- Testing
- Cooling Gel, Cold Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Baskent University
Upper Respiratory Tract Infections, Lower Respiratory Tract Infections
Maternal Vitamin D for Acute Respiratory Infections in Infancy
There is a growing body of data suggesting that vitamin D modulates the host's immune response to acute respiratory infection (ARI).
- Trial name
- MDARI (NCT02388516)
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 1,214 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Upper Respiratory Infections
Effects of Echinacea in Children
The goal of the this study is to determine if Echinacea purpurea stimulates the immune system in children. For the study, 40 healthy children, 6-11 years old will be randomized to receive Echinacea purpurea or placebo for 10 days…
- Trial name
- NCT00773435
- Testing
- Echinacea purpurea 100 mg/ml in liquid formulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Washington
Hepatocellular Carcinoma, Hepatic Metastasis
Palliative Radiotherapy (RT) for Liver Metastases (Mets) and Hepatocellular Carcinoma (HCC)(COLD 4)
Palliative radiotherapy is radiation treatment given to help reduce pain or discomfort, or other symptoms related to cancer. This is used commonly for cancer that has spread to the bones and brain, and for many other primary…
- Trial name
- NCT00923897
- Testing
- Palliative RT
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Upper Respiratory Infection, Acute Bacterial Sinusitis
Improving Antibiotic Prescribing for Pediatric Respiratory Infections by Family Physicians With Peer Comparison
Findings from an ongoing improvement project to improve antibiotic prescribing for children and adolescents for three acute respiratory tract infections (ARTIs: upper respiratory tract infection, acute bacterial sinusitis, and…
- Conditions
- Upper Respiratory Infection, Acute Bacterial Sinusitis, Acute Otitis Media
- Trial name
- NCT04588376
- Testing
- Peer comparison feedback monthly
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Herb Clegg
Traumatic Brain Injury
Cold-stored Platelet Early Intervention in TBI
The Cold Stored Platelet Early Intervention in Traumatic Brain Injury (CriSP-TBI) trial is a proposed 3 year, open label, single center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent…
- Trial name
- CriSP-TBI (NCT04726410)
- Testing
- Cold Stored Platelets, Standard Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jason Sperry
Post ERCP Pancreatitis
Ice Cold Water Flushing of the Ampulla After Endoscopic Sphincterotomy to Reduce Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is an essential diagnostic and therapeutic tool used to manage diseases of the pancreatic and biliary systems.
- Trial name
- ERCP (NCT07677397)
- Testing
- Ice cold water flushing post ERCP
- Volunteers
- 210 people
- Sponsor
- Oman Ministry of Health
Immunomodulation, Respiratory Tract; Infection, Upper (Acute)
Effect of an Immune-boosting Food Supplement on the Severity and Frequency of Pediatric Respiratory Tract Infections
The goal of this clinical trial is to evaluate the efficacy of the product in developing immune reinforcement that results in decreased susceptibility to respiratory infections of viral origin in children aged 3 to 10 years with…
- Trial name
- NCT06218225
- Testing
- Verum
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Chronic Obstructive Lung Disease (COLD)
ANTEAB: a Study of Early Antibiotherapy in the ICU Management of Acute Exacerbations of COPD
Intensive Care Unit (ICU) admission for acute exacerbation of chronic obstructive lung disease (COLD) is a major cause of morbidity and mortality in such patients. Although bacterial of mortality in such patients.
- Trial name
- NCT00190437
- Testing
- Amoxicillin-clavulanic
- Where
- 2 sites in France
- Volunteers
- 520 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chilblains, Perniosis
Assessment of Vasomotion of People With Idiopathic Chilblains
Chilblains, also known as perniosis, is a non-freezing cold injury causing painful inflammatory skin lesions. Chilblains typically affect the dorsal feet or hands, causing inflammatory skin lesions that are often painful, and…
- Conditions
- Chilblains, Perniosis, Thermoregulation
- Trial name
- NCT06237517
- Testing
- Assessment of Vasomotion of People With Idiopathic Chilblains
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
RSV Infection, Children, Only
RSV Burden in Outpatient and Hospital Settings
Strengthening outpatient low respiratory tract infection surveillance to document the burden of Respiratory Syncytial Virus (RSV)
- Conditions
- RSV Infection, Children, Only, Outpatient, Otitis
- Trial name
- Oursyn (NCT04743609)
- Testing
- nasopharyngeal samples
- Where
- France
- Volunteers
- 1,900 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Cough
Transpulmin Suppository and Guaiacol Compared to Transpulmin Syrup in Pediatric Participants With Productive Cough
This study evaluates the non-inferiority of Suppository Transpulmin and Suppository Guaiacol compared to Transpulmin Syrup in the treatment of cough with secretion of infectious origin in children between two and six years old.
- Trial name
- Transpulmin (NCT02581397)
- Testing
- Transpulmin suppository, Guaiacol suppository, Transpulmin syrup
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Knee Pain, Osteoarthritis
The Effects of the Electro, Heat and Cold -Therapy During Physiotherapy Treatment in Osteoarthritis(OA) of KNEE
The objective of this clinical trial is to evaluate the pain relief and daily functioning improve, in patients suffering of Osteoarthritis of knee, with HOT/COLD/ Electro therapy during physiotherapy treatment
- Trial name
- NCT01112319
- Testing
- Elf care, control group
- Where
- Israel
- Sponsor
- Meir Medical Center
Influenza
Trial to Investigate Viral Shedding in Healthy Children Vaccinated With Vaccine Virus Liquid (CAIV-T)
The primary objective of this study was to determine the proportion of subjects, seronegative to all three strains of influenza, as defined by a serum hemagglutination inhibition antibodies (HAI) antibody titer of <1:10, who shed…
- Trial name
- NCT00192387
- Testing
- CAIV-T, Liquid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Labor Pain
Endorphin at Labor Pain and Acupressure
This study was performed to determine the impact of different acupressure procedures, performed on women's hands during labor, on endorphin levels and labor pain perception. The sample consisted of 140 pregnant women.
- Trial name
- NCT04367038
- Testing
- Warm Acupressure, Cold Acupressure , Conventional Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Serap ÖZTÜRK ALTINAYAK
Local Application / Packing Too Cold
Effect of Cold Application Materials on Pain During Chest Tube Removal
Background: Despite being an important treatment intervention, chest tube causes severe pain during removal because it attaches to the endothelium in the chest cavity.
- Trial name
- NCT04200859
- Testing
- Cold application
- Volunteers
- 180 people
- Sponsor
- Mersin University
Upper Respiratory Tract Infections, Urinary Tract Infections
Routine Prescription Feedback and Peer Comparison to Lower Antibiotic Prescriptions in Primary Care
To evaluate the effect of a continuous postal and web-based feedback and peer comparison system of individual antibiotic prescription rates on the prescription behaviour of primary care physicians in Switzerland.
- Trial name
- NCT01773824
- Testing
- Antibiotic prescription feedback, No Feedback
- Where
- Switzerland
- Volunteers
- 2,900 people
- Sponsor
- University Hospital, Basel, Switzerland