Clinical trials: Cold Symptom
Obese Patients With Bariatric Surgery
The Effect of Cold Application on Nausea and Vomiting After Bariatric Surgery
Obesity is a chronic disease resulting from an excess of body fat mass relative to lean body mass, characterized by a deterioration in the individual's quality of life and health (Kayar and Utku, 2013; Usta and Çavdar, 2013; Tam…
- Trial name
- NCT07825779
- Testing
- ICE
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Pain, Hyperalgesia
Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models
MOR-NRI like Tapentadol are expected to reduce signs and symptoms of central sensitisation besides effectively reducing pain intensity in pain.
- Conditions
- Pain, Hyperalgesia, Allodynia
- Trial name
- NCT01615510
- Testing
- Tapentadol immediate release
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Chronic Obstructive Lung Disease
Procalcitonin To Reduce Antibiotics in Chronic Obstructive Lung Disease (ProToCOLD)
Title: Pro-to-COLD, Procalcitonin to Chronic Obstructive Lung Disease, COLD: Chronic Obstructive Lung Disease, Regarding: Patients hospitalized with suspected acute exacerbation of COPD + / - pneumonia.
- Trial name
- ProToCOLD (NCT01950936)
- Testing
- Discontinuation of Antibiotcs
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Danish Procalcitonin Study Group
Hyperthermia
Cold Water Immersion Stirring in Hyperthermic Individuals
The best way to cool a very hot person is using cold water immersion, however, the optimization of this technique has not been established.
- Trial name
- NCT04613843
- Testing
- Water Stirring, No Water Stirring
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Respiratory Tract Infections (RTI), Influenza-like Illness
Clinical Assessment of Respiratory Events for Kids: Integrating Diagnostics and Stewardship
This study, called Care4Kids, aims to improve the management of respiratory infections in children visiting emergency departments.
- Conditions
- Respiratory Tract Infections (RTI), Influenza-like Illness, Children
- Trial name
- CARE4KIDS (NCT07453914)
- Testing
- SPOTFIRE R
- Where
- 3 sites in France, Greece and 1 more
- Volunteers
- 720 people
- Sponsor
- BioMérieux
Respiratory Tract Infections, Bronchiolitis Obliterans
Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post Allotransplant
For many patients with blood cancers, stem cell transplantation from a family member or from an unrelated donor remains the only potentially curative option.
- Conditions
- Respiratory Tract Infections, Bronchiolitis Obliterans, Cryptogenic Organizing Pneumonia, Lung Diseases, Interstitial
- Trial name
- NCT01432080
- Testing
- Prednisone, Azithromycin, Montelukast
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Knee Prosthesis, Cryotherapy
Pressurized Cold Application for Patients Total Knee Prosthesis Surgery
This study was conducted to examine the effects of pressurized cold applicatıon for patients total knee prosthesis surgery.
- Conditions
- Knee Prosthesis, Cryotherapy, Pain, Patient Satisfaction
- Trial name
- NCT05233423
- Testing
- compressed cold therapy bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Restless Legs Syndrome, Pregnant
The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome
This study was planned as a randomized controlled study to determine the effect of hot and cold water application on complaints and sleep quality in pregnant women with restless legs syndrome (RLS).
- Conditions
- Restless Legs Syndrome, Pregnant, Sleep Disorder
- Trial name
- RLS (NCT04786314)
- Testing
- Hot Water Application, Cold Water Application
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hemodialysis Complication, Muscle Spasm
Hot and Cold Compress in Hemodialysis
Aims and objectives. To examine and compare the effects of hot and cold compresses administration on muscle cramps, fatigue, and comfort in hemodialysis (HD) patients. Background.
- Conditions
- Hemodialysis Complication, Muscle Spasm, Fatigue
- Trial name
- NCT04681521
- Testing
- Hot and Cold compress, nursing interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Nausea and Vomiting, Postoperative
The Effect of Cold Steam Application on Nausea and Vomiting
The aim of this study was to determine the effect of cold vapour applied to patients undergoing laparoscopic abdominal surgery primarily on nausea and vomiting and secondarily on antiemetic requirement, patient satisfaction and…
- Trial name
- NCT06760871
- Testing
- nebulised distilled water
- Where
- Turkey (Türkiye)
- Sponsor
- Trakya University
Cardiovascular Disease Other, Bleeding
Transfusion of Cold-stored Platelet Concentrates
This study will investigate the effects of Leukocyte reduced cold-stored platelet transfusions used in treatment of immediate postoperative blood loss in patients undergoing thoracic surgery in combination with extracorporal…
- Conditions
- Cardiovascular Disease Other, Bleeding, Surgery
- Trial name
- 4CPLT (NCT02495506)
- Testing
- Cold stored platelets, Room temperature platelets
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Haukeland University Hospital
Tinea Pedis
Atmospheric Pressure Cold Plasma for Moderate-to-severe Tinea Pedis
Tinea pedis (athlete's foot) is a common and highly contagious fungal infection of the feet. Moderate-to-severe cases present with extensive skin lesions, severe symptoms, frequent recurrences, and increased risk of…
- Trial name
- NCT07056660
- Testing
- Active CAP therapy, standard care
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Shenyang Medical College
Paroxysmal Nocturnal Hemoglobinuria, Marchiafava-Micheli Syndrome
Efficacy and Safety of Elizaria® vs. Soliris® in Patients With PNH
It is a multicenter, open-label, randomized, parallel-group study of the efficacy and safety of Elizaria® (eculizumab, GENERIUM JSC, Russia) versus Soliris® (Alexion Pharma GmbH, Switzerland) in patients with paroxysmal nocturnal…
- Conditions
- Paroxysmal Nocturnal Hemoglobinuria, Marchiafava-Micheli Syndrome, Paroxysmal Hemoglobinuria
- Trial name
- NCT04463056
- Testing
- Elizaria®, Soliris®
- Where
- 4 sites in Russia
- Volunteers
- 32 people
- Sponsor
- AO GENERIUM
Cryopyrin Associated Periodic Syndrome
A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZYIL1 in Subjects With Cryopyrin Associated Periodic Syndromes (CAPS)
ZYIL1 is expected to show benefit in patients with CAPS. The present study aims to determine the safety, tolerability, pharmacokinetics, and pharmacodynamics of ZYIL1 when administered to subjects with CAPS.
- Trial name
- NCT05186051
- Testing
- ZYIL1 capsule
- Where
- Australia
- Volunteers
- 3 people
- Sponsor
- Zydus Lifesciences Limited
Aortic Valve Disease, Ischemia-reperfusion Injury
The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement
A group of 150 patients undergoing aortic valve replacement procedure will be randomized either into del Nido cardioprotection protocol (75 participants) or into the cold blood cardioplegia protocol (75 participants).
- Trial name
- NCT03818126
- Testing
- del Nido cardioplegia, cold blood cardioplegia
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Pawel Buszman
Virus Diseases in Children
A Study to Investigate the Effect of Probiotics (Limosilactobacillus Reuteri DSM 17938 and Limosilactobacillus Reuteri DSM 33633) on Symptoms of Viral Upper Respiratory Tract Infections in Children
This study investigates the effect of Limosilactobacillus reuteri probiotic strains (DSM 17938 and DSM 33633) on symptoms of viral upper-respiratory tract infections in children.
- Trial name
- NCT07870824
- Testing
- Probiotics (L. reuteri DSM 17938 and L. reuteri DSM 33633)
- Where
- Hungary
- Volunteers
- 194 people
- Sponsor
- Milosevits Gergely
Pain, Diabetes Mellitus
Cold Spray for Insulin-Injection Pain in the Emergency Department
This randomized, double-blind, placebo-controlled, within-patient crossover trial evaluated whether a vapocoolant (cold) spray applied before subcutaneous insulin injection reduces injection pain compared with a placebo…
- Trial name
- NCT07728162
- Testing
- Cold (vapocoolant) spray
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Abant Izzet Baysal University
Pain Management, Emergency Unit
The Effectiveness of Local Dry Cold, Hot and Vibration Applications in Peripheral Intravenous Catheterization
Aim: The aim of the present study was to examine the effect on venous dilation, procedure duration and pain severity of local hot, cold and vibration applications performed on the intervention area before peripheral intravenous…
- Conditions
- Pain Management, Emergency Unit, Diarrhea, Nausea
- Trial name
- NCT06378424
- Testing
- Cold Application, Heat Application, Vibration Application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Uludag University
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obesity, Metabolic Syndrome
Brown Adipose Tissue as a Mechanistic Determinant of Semaglutide Treatment Response in Obesity (BAT-Sema Study)
This study investigates whether the activity of brown adipose tissue (BAT) - a special type of fat that burns energy as heat - can predict how well individuals with obesity respond to semaglutide (Wegovy), a once-weekly…
- Conditions
- Obesity, Metabolic Syndrome, Brown Adipose Tissue
- Trial name
- BAT-Sema (NCT07621640)
- Testing
- Semaglutide (Wegovy®), ¹⁸FDG-PET/CT with cold stimulation, Liver MRI (PDFF + MRE)
- Where
- 2 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Hallym University