Clinical trials: Cold Symptom
Gallstone
Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies
Double blind RCT comparing elective laparoscopic cholecystectomy using warmed, humidified gas (new) against laparoscopic cholecystectomy with cool, dry gas (usual). Sample size of 200 patients.
- Trial name
- NCT00792389
- Testing
- Warm humidified C02, Cool dry C02
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Improvement in Immune Cell Function in Elderly Humans
GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults
A randomized, double blind placebo-controlled parallel intervention in adults over the age of 50 will be performed. Participants will receive a supplement capsule containing placebo (Crystalline Cellulose) or 500mg of Setria®…
- Trial name
- NCT02316925
- Testing
- Setria glutathione supplement, Crystalline Cellulose
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Obesity (Disorder)
JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity
The Joule MARS study is a single center, randomized, open label clinical trial aiming to explore the metabolic adaptations that occur in response to weight management in adolescents with obesity.
- Trial name
- JOULE-MARS (NCT06852391)
- Testing
- Semaglutide Pen Injector, Behavioural Lifestyle Program (BLP)
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- McMaster University
Obesity
Chronic Intermittent Cold Exposure on Weight Loss
1. To test whether chronic intermittent cold exposure is more effective in programmed body weight loss when compared to conventional programmed weight loss. 2. To measure the metabolic responses (e.g.
- Trial name
- CICE (NCT01312090)
- Testing
- Whole body cryotherapy, counseling and behavioral therapy for weight loss
- Volunteers
- 20 people
- Sponsor
- Helsinki University Central Hospital
Pain
Testing Protocol for Cold-sensing Fibers
This project aims to evaluate whether electrical stimulation can modulate the cold detection threshold and the cold pain threshold.
- Trial name
- Cold (NCT05192577)
- Testing
- Electrical stimulation
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Local Application/Packing Too Cold, Patient Satisfaction
The Effect of Cold Application on Nausea and Vomiting in the Early Postoperative Period
As a result of the literature review, it has been seen that it has not yet been clarified whether cold application methods are effective on postoperative nausea and vomiting, and academic studies on this subject are needed.
- Conditions
- Local Application/Packing Too Cold, Patient Satisfaction, Postoperative Nausea and Vomiting
- Trial name
- NCT05888818
- Testing
- Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Hypersensitivity, Immediate, Autoinflammatory Syndromes
Pathogenesis of Physical Induced Urticarial Syndromes
Background: Urticaria is a common itchy skin disorder that may occur spontaneously or on exposure to a physical trigger (called physical urticaria).
- Conditions
- Hypersensitivity, Immediate, Autoinflammatory Syndromes, Physical Urticaria, Familial Cold Autoinflammatory Syndrome
- Trial name
- NCT00887939
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Healthy, Obese
Circadian Rhythmicity in Cold-induced Thermogenesis
This study aims to investigate whether maximum cold-induced non-shivering thermogenesis (e.g. thermogenesis as a consequence of BAT activity) differs between morning and evening.
- Conditions
- Healthy, Obese, Glucose Intolerance
- Trial name
- COLDR (NCT04406922)
- Testing
- Personalized cooling protocol
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Muckle-Wells Syndrome, Schnitzler Syndrome
Safety and Tolerability of Rilonacept in Muckle-Wells Syndrome (MWS) or Schnitzler Syndrome (SchS)
This is a single-center open label study of the IL-1 transfusion protein rilonacept in subjects with Muckle-Wells syndrome (MWS), or Schnitzler syndrome (SchS) in Germany.
- Trial name
- ACCILTRA1 (NCT01045772)
- Testing
- rilonacept
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Charite University, Berlin, Germany
Hamstring Injuries, Hamstring Muscle Repair
Thermal Therapies in the Treatment of Muscle Injuries
Muscle strain injuries represent one of the most prevalent injuries in athletes. Despite this high injury prevalence, there is no evidence to support some of the currently used therapeutic strategies.
- Conditions
- Hamstring Injuries, Hamstring Muscle Repair, Hamstring Muscles, Hamstring Rupture
- Trial name
- NCT07045129
- Testing
- Cold water immersion, Hot water immersion, Physiotherapy only
- Where
- Qatar
- Volunteers
- 135 people
- Sponsor
- Aspetar
Cryopyrin-Associated Periodic Syndromes, Amyloidosis
Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load
Background: Anakinra is a drug used to treat people with certain diseases that affect their immune systems. Sometimes anakinra can cause proteins under the skin to clump together.
- Trial name
- NCT06974877
- Testing
- 124I AT-01
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cold, Cold Symptom
Ability of Beta-glucan Supplementation to Augment Immune Function
This proposed study is designed to assess the efficacy of a capsule containing beta-glucan taken orally daily as compared to a placebo capsule on the URTI symptoms, and the immune response change in marathon runners
- Conditions
- Cold, Cold Symptom, Flu, Flu Symptom
- Trial name
- NCT03769012
- Testing
- Beta-Glucan
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Wheezing, Upper Respiratory Tract Infections
Nasal Resveratrol and Wheezing Episodes in Preschool Children
As most of the upper airways infections (UAI) leading to wheezing are secondary to viral triggers, the possible antinflammatory and antiviral role of resveratrol has been suggested in several studies, both in vitro and in vivo.
- Trial name
- RSVchild (NCT04689412)
- Testing
- Resveratrol
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Pedunculated Colorectal Polyps, Haemorrhage
Cold Snare Polypectomy Versus Hot Snare Polypectomy for Resection of Small Pedunculated Polyps
Endoscopic resection of pedunculated polyps mainly focuses on how to prevent bleeding, and also needs to pay attention to the convenience of resection and the integrity of resection, which means that different endoscopic…
- Trial name
- NCT06097650
- Testing
- cold snare polypectomy, hot snare polypectomy
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Ningbo No. 1 Hospital
Lower Respiratory Tract Infection, Acute Bronchitis
Evaluating a Host-response Based Diagnostic for Distinguishing Between Bacterial and Viral Etiology in Patients With Lower Respiratory Tract Infection (LRTI)
The purpose of this study is to validate the diagnostic accuracy of a novel host-response based diagnostic tool for differentiating between bacterial and viral etiologies in adult patients aged 18 years and older with clinical…
- Conditions
- Lower Respiratory Tract Infection, Acute Bronchitis, Pneumonia, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- OBSERVER (NCT03011515)
- Where
- Israel
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Hand Injuries and Disorders
Cross-cultural Adaptation and Validation of the CISS and the PWES Questionnaire in Patients With Hand Pathologies.
The primary objective of the study is to do translation, cross-cultural adaptation and validation of the CISS and PWES questionnaire in French. No available translation exist in French.
- Trial name
- NCT04646343
- Testing
- administration of F-CISS and F-PWES pre version, administration of definitive version of F-CISS and F-PWES plus F-DASH, F-HFS and F-SF 36
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Clinique Romande de Readaptation
Allergic Rhinitis, Asthma
Development of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen
The investigators propose the development of a range of nasal spray challenge models to study the way the nose can respond to different types of nasal challenge that elicit different forms of inflammation.
- Conditions
- Allergic Rhinitis, Asthma, Latent Tuberculosis
- Trial name
- NCT02090374
- Testing
- Poly ICLC, Poly I:C, R848
- Where
- United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Blood Pressure, Blood Loss
LBNP Tolerance With Skin Warming After Exercise Cold Stress
Assess the effect of skin rewarming during lower body negative pressure upon arterial blood pressure and tolerance to simulated blood loss after exercise in the cold.
- Trial name
- NCT06279897
- Testing
- Skin Surface Rewarming, Skin Surface Warming, Skin Surface Heating
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Acute Lower Respiratory Tract Infection, Pneumonia
Fast Identification of Pathogen in the Setting of Hospital-acquired Pneumonia Using Ion Mobility Spectrometry
With this study the investigators want to determine, if a fast identification of germs, causing hospital-acquired infections of the lower respiratory tract, is possible through the use of MCC-IMS technology - a method that allows…
- Trial name
- NCT01624181
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Göttingen