Clinical trials: Colic, open to volunteers
Cancer Colon
Clinical and Biological Database in Colon Cancer and Colic Tumors
Developement of a clinical and biological database in colon cancer and colic tumors in order to better understand tumor invasion and metastatic scattering processes.
- Trial name
- BCBCOLON (NCT03976960)
- Testing
- Biological collection
- Where
- 2 sites in France
- Volunteers
- 600 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Infant Colic, Gut Microbiota
Effect of a Dietary Supplement vs Low-dosage Product on Infant Gastrointestinal Discomfort and Colics
The goal of this clinical trial is to verify whether a food supplement is effective in treating infantile colic of infants aged between 21 days and 9 months and the colonization ability of the gut microbiota by measuring faecal…
- Trial name
- DISIC (NCT07017244)
- Testing
- Verum, Active comparator
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Anastomotic Leak, Colon Cancer
Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy
The primary aim of the study is to show that the ileo-colic anastomosis leakage rate until the first 30 days after surgery using MonoPlus® suture material for anastomosis construction after right hemicolectomy is not inferior to…
- Conditions
- Anastomotic Leak, Colon Cancer, Right Hemicolectomy
- Trial name
- LICOSARH (NCT07132970)
- Testing
- Monoplus Suture Material
- Where
- 4 sites in Germany
- Volunteers
- 249 people
- Sponsor
- Aesculap AG
Colon Anastomosis
Flexagon Plus OTOLoc Colon Anastomosis in Patients Undergoing Surgery
The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon SFM system plus OTOLoc when used to create a Ileo-colic and Colo-colonic anastomoses in participants undergoing colon surgery.
- Trial name
- FOCUS (NCT06915818)
- Testing
- Ileo-colic and colo-colonic Anastomosis with Flexagon SFM and OTOLoc
- Where
- 2 sites in Chile, India
- Volunteers
- 65 people
- Sponsor
- GI Windows, Inc.
Obesity, Type2 Diabetes
Small Bowel Diversion
In an effort to replicate metabolic surgery's durable results in metabolic disease while minimizing its risks, two innovative methods has been created.
- Trial name
- NCT06374368
- Testing
- jejuno-ileal diversion, jejuno-colic diversion
- Where
- 2 sites in Czechia
- Volunteers
- 80 people
- Sponsor
- University of Ostrava
Infantile Colic, Gastroesophageal Reflux (GER)
BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months
Infants often experience functional gastrointestinal symptoms (e.g., colic, excessive gas, regurgitation, constipation, or loose stools) that distress families and may reflect an imbalance of the gut microbiome.
- Conditions
- Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea
- Trial name
- CTBE2503 (NCT07148583)
- Testing
- BioAmicus Complete, Usual Care (No Probiotic)
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Infantile Colics, Constipation
Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete
This is a randomized, single-blind, placebo-controlled study to evaluate the efficacy of the dietary supplement BioAmicus Complete (oral drops; a mixture of 10 strains of lacto- and bifidobacteria) in managing functional…
- Conditions
- Infantile Colics, Constipation, Infantile Diarrhea, Atopic Dermatitis
- Trial name
- NCT07444008
- Testing
- BioAmicus Complete
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- NovoNatum Ltd
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
Relief Efficacy of Lidocaine Versus Morphine for Acute Renal Colic in the Emergency Department
The opioid epidemic continues to be a major public health crisis in the United States. According to the Center for Disease Control, approximately 8 million Americans reported misusing prescription opioids in 2023, with over 5…
- Conditions
- Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia, Opioid Use During Medical Care
- Trial name
- RELIEF-RC (NCT07536594)
- Testing
- Lidocaine, Morphine 0,1 mg/kg
- Volunteers
- 250 people
- Sponsor
- Loma Linda University
Metastatic Colorectal Cancer
18FFDG PET/CT for Early Evaluation of Chemotherapy Efficacy in Metastatic Colic Adenocarcinoma
The metastatic colo-rectal cancer (especially with hepatic metastatic lesions, but also peritoneal or pulmonary lesions) is a major public health issue, because of its frequency, the heavy treatments and the cost of new…
- Trial name
- TEP-PREDICT (NCT05531045)
- Testing
- PET/CT
- Where
- France
- Volunteers
- 222 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer Surgery, Perfusion Imaging
Effect of Preserving the Left Colic Artery on Proximal Bowel Perfusion
Patients with rectal or rectosigmoid cancer undergoing radical resection will be randomly assigned to either high-tie (HT) or low-tie (LT) ligation of the Inferior Mesenteric Artery (IMA).
- Conditions
- Rectal Cancer Surgery, Perfusion Imaging, Anastomosis, Leaking
- Trial name
- NCT06982664
- Testing
- High Tie of Inferior Mesenteric Artery, Low Tie of Inferior Mesenteric Artery
- Volunteers
- 143 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Healthy, Healthy Nutrition
The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial
The goal of The BEGIN Study, a randomized controlled double-blinded intervention trial, is to learn if probiotics, with Bifidobacterium longum subspecies infantis Bifin02 (B.
- Trial name
- BEGIN (NCT06452199)
- Testing
- B. infantis
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infantile Colic
0-3 Months Infantile Colic The Effect of Ocean Sound on Babies
Infant colic is one of the most common health problems in newborns and infants. It is a syndrome of unknown cause, occurring in attacks, weakened by clenched fists, hardening of the abdomen, flatulence, pulling the legs to the…
- Trial name
- NCT06743971
- Testing
- ocean sound concert
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Infantile Colic
Effect of Probiotics on Infantile Colic Symptoms
The aim of this clinical trial is to assess the impact of B. lactis B94 on participants with infantile colic. It is hypothesized that participants given the probiotic formula will have a significant reduction in their crying…
- Trial name
- EPIC (NCT06385054)
- Testing
- Probiotic
- Where
- 10 sites in France
- Volunteers
- 70 people
- Sponsor
- Lallemand Health Solutions
Renal Colic
Comparative Efficacy of IV Dexamethasone vs. Nebulized Terbutaline for Renal Colic Pain in the ED
Adult patients (18-55 years of age) with clinical diagnosis of acute renal colic (sudden sharp colic flank pain with or without radiation to genitalia or groin and with or without urinary symptoms) who had pain score of 5 or more…
- Trial name
- NCT06980727
- Testing
- Terbutaline 2.5 mg, Dexamethasone
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
The Use of AR / VR in Patients Presenting to the ED With Renal Colic
Utilization of VR / AR Calming as an adjunct to pharmacologic pain management for Renal Colic in Emergency Department Patients
- Trial name
- NCT07070401
- Testing
- Commercial AR/VR Headset with Calming App, Pharmacologic Standard of Care Alone
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Community Medical Center, Toms River, NJ
Renal Colic
Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation and Dexketoprofen in Renal Colic
The aim of this study was to compare the analgesic efficacy of transcutaneous electrical nerve stimulation (TENS) and dexketoprofen trometamol in patients presenting to the emergency department due to renal colic.
- Trial name
- NCT07176572
- Testing
- TENS, Dexketoprofen Trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Adiyaman University Research Hospital
Massage Effect
Vimala Massage Infantile Colic, Sleep and Development Levels
Objective: The effect of Vimala massage applied by parents on infantile colic, sleep and developmental levels of infants will be investigated.
- Trial name
- VIMCOLSLEEP (NCT06993701)
- Testing
- Vimala Massage Training for Fathers, Control Intervention, Vimala Massage Training for Mothers
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Renal Colic
Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics
Treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this subject.
- Trial name
- NAP-RC (NCT05722782)
- Testing
- Piroxicam, Acetaminophen
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Colorectal Cancer, Diverticular Diseases
Initial Safety of SFM Plus OTOLoc for Creating Side-to-side or End-to-side Colorectal Anastomoses
The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon 25mm SFM system plus OTOLoc when used to create a side-to-side Ileo-colic, Colo-colonic and side-to-side or end-to-side colorectal…
- Trial name
- Colonic (NCT07276529)
- Testing
- Flexagon Self Forming Magnet Anastomosis Plus OTOLoc for Creating side-to-side Colon Anatomoses
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- GI Windows, Inc.