Clinical trials: Collagen Diseases
Psoriatic Arthritis, Hand Rheumatism
Hand Exercises in Psoriatic Arthritis
This study is a randomized controlled study examining the effects of 8-week hand home exercises on grip strength, functionality, disease activity and quality of life in patients with PsA.
- Trial name
- NCT06263634
- Testing
- Hand exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Akdeniz University
Obesity & Overweight, Collagen Protein
Collagen Supplements and Post-MBS Muscle Mass/Body Image
This prospective, observational cohort study aims to evaluate whether the use of collagen-containing supplements is associated with differences in muscle mass, body composition, and body image among patients who have undergone…
- Conditions
- Obesity & Overweight, Collagen Protein, Bariatric Surgery, Metabolic and Bariatric Surgery
- Trial name
- NCT07809152
- Testing
- Collagen-containing supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mudanya University
Keloid Scar Following Surgery, Scars, Hypertrophic
Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry
Measuring the volumes of hypertrophic scars and keloids, two specific kind of scars, over different points in time in patients who have undergone surgery and evaluate 3D-cameras as a possible measuring and documenting tool…
- Conditions
- Keloid Scar Following Surgery, Scars, Hypertrophic, Scar Keloid
- Trial name
- NCT06806735
- Testing
- 3D-Pictures
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Allergic Reaction
Allergy Potential of Omeza Collagen Matrix in Human Subjects Using the Skin Prick Method
Single-center, monadic, one day study utilizing the skin prick method to assess the allergy potential of Omeza Collagen Matrix in Human Subjects
- Trial name
- NCT04510376
- Testing
- Test Article, Positive Control, Negative Control
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Scar Keloid
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars
Summary: Keloids and hypertrophic scars are benign fibrous growth, differing mainly by overgrowth beyond the initial defect in keloid whereas hypertrophic scar is confined to initial lesion and tends to regress over the years.
- Trial name
- NCT04812626
- Testing
- 5-Fluorouracil
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Rheumatoid Arthritis, Spondyloarthritis
Vaccination Against SARS-Cov2 (COVID-19) in Chronic Inflammatory Rheumatism and Factors Determining Its Decision.
Rheumatoid arthritis and spondyloarthritis (ankylosing spondylitis and psoriatic arthritis mainly) are chronic inflammatory rheumatism (RIC), frequently onset in young adults. The prevalence is respectively 0.3 to 0.8% and 0.4%.
- Trial name
- VACCI-RIC (NCT04970550)
- Testing
- Non intervention
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hopital Nord Franche-Comte
Osteogenesis Imperfecta
Post-market Observational Study on JTIN Telescopic Nail in Osteogenesis Imperfecta Pediatric Patients
This study has been planned as part of the Orthofix Srl post-market active surveillance plan for the collection of data on both the clinical performance and the safety profile of the JTIN.
- Trial name
- JTIN (NCT05612139)
- Testing
- JTIN implantation surgery
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Orthofix s.r.l.
Keloid
Genetic Analysis of Familial Keloids
The purpose of this study is to identify the gene or genes responsible for keloid formation. Keloids are raised scars on the skin that form after a minor injury.
- Trial name
- NCT00008502
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetic Foot Ulcer
A Study to Evaluate the Efficacy of a Purified Native Type 1 Collagen Extracellular Matrix With Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers
This prospective, multi-center, randomized, controlled modified platform Trial compares Purified Native Type 1 Collagen Extracellular Matrix with Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care versus…
- Trial name
- PREPARE (NCT06618612)
- Testing
- Standard of Care, PuraPly AM, PuraPly XT
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Organogenesis
Liver Cancer, Hemorrhage Liver
Standard of Care Versus Hemopatch® During Liver Resection
This multicentre prospective and randomized study aims to compare the sealant effect after surgical liver resection of a new collagen - polyethylene glycol hemostatic / sealant patch (Hemopatch) vs standard of care.
- Conditions
- Liver Cancer, Hemorrhage Liver, Bile Leak, Surgery
- Trial name
- IBERLIVER (NCT03166683)
- Testing
- Hemopatch, Standard of care
- Volunteers
- 284 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Bone Loss
Lateral Ridge Augmentation Using Cross-linked or Non-cross-linked Collagen Membrane
The objective of the present trial is to test clinically, radiographically and histologically , in a lateral alveolar ridge augmentation model (without simultaneous implant placement) the efficiency in supporting bone formation…
- Trial name
- NCT04402671
- Testing
- non-cross-linked porcine skin collagen membrane, glutaraldehyde cross-linked bovine collagen membrane
- Where
- Lebanon
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Scleroderma, Systemic Sclerosis
The Effect of Physiotherapy Program in Scleroderma Patients
The aim of this study was to investigate the effectiveness of physiotherapy and rehabilitation program on hand involvement of patients with scleroderma and to compare the effects of home rehabilitation program and rehabilitation…
- Conditions
- Scleroderma, Systemic Sclerosis, Hand Rheumatism, Physiotherapy
- Trial name
- NCT04179292
- Testing
- Hand Therapy by Physiotherapist, Hand Therapy as home program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Aortic Diseases, Aortic Dissection
Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes
The aorta is the principal arterial vessel arising from the left heart that transfers blood to the body. Certain genetic and familial disease processes are known to weaken the aortic wall resulting in dilation and potential…
- Conditions
- Aortic Diseases, Aortic Dissection, Aortic Aneurysm, Thoracic, Aortic Ectasia
- Trial name
- NCT05389865
- Testing
- Surgery on the proximal aorta (aortic root +/- ascending aorta), Patients diagnosed with thoracic aortopathy but not operated upon
- Where
- United Kingdom
- Volunteers
- 1,662 people
- Sponsor
- Golden Jubilee National Hospital
Keratoconus
Iontophoretic Transepithelial Collagen Cross-linking Versus Epithelium-off Collagen Cross-linking in Pediatric Patients. Three Year Follow up.
To compare 3 year iontophoretic transepithelial corneal cross-linking (I-ON CXL) outcomes with epithelium-off collagen cross-linking (epi-off CXL)in pediatric patients.
- Trial name
- NCT03753009
- Testing
- corneal cross-linking
- Volunteers
- 28 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Epidermolysis Bullosa Dystrophica
Self-Assembled Skin Substitute for the Treatment of Epidermolysis Bullosa
Single patient study. Patient diagnosed with dystrophic epidermolysis bullosa presenting chronic open wounds that are not responding to dressings, topical preparations (antimicrobials, antibiotics) and systemic agents…
- Trial name
- SASS (NCT04171661)
- Testing
- SASS
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- CHU de Quebec-Universite Laval
Diabetes Mellitus, Type 2
Investigation for Health Efficacy of Infrared-C Radiation on Diabetes Patients in Senior's Activity Center
Hyperglycemia caused by diabetes will bring us the long-term damage，it causes glycation. The combination of sugar molecules and protein molecules will transform to advanced glycation end products (AGEs) and produce a lot of free…
- Trial name
- NCT04177420
- Testing
- FIR-C mattress, FIR-C abdominal pad, fake FIR-C mattress
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- Nanhua University
Gonarthrosis
Intraarticular Collagen in Patients With Gonarthrosis
The objective of this clinical trial is to verify the effectiveness of polyvinyl pyrrolidone collagen in all patients with symptomatic gonarthrosis grades II-IV in patients over 40 years of age.
- Trial name
- NCT06275880
- Testing
- Intra-articular infiltration of PVP Collagen, Rehabilitation
- Where
- Mexico
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Skin Diseases, Hypertrophic Scar
Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases
Piezoelectric drived microneedling treats refractory skin disorders using hollow microneedles assisted by ultrasound. Mechanically, the injection of medicine by hollow microneedling could makes the distribution of medicine more…
- Conditions
- Skin Diseases, Hypertrophic Scar, Keloid, Plantar Wart
- Trial name
- NCT05488860
- Testing
- Triamcinolone acetonide(scar)/5-ALA(others), Piezoelectric drived microneedling, 5-ALA (a photosensitizer for photodynamic therapy).
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Osteearthritis, Joint Damage
Effect of Agar/Collagen-based Compounds on Osteoarticular Pain: Randomized Triple-blind Clinical Trial
Joints-comprising bone, cartilage, ligaments, and synovial fluid-enable stable daily movement but may deteriorate with age, excess body weight, overuse, injury, or disease.
- Conditions
- Osteearthritis, Joint Damage, Inflammation, Cartilage Damage
- Trial name
- AGARTROSIS (NCT07318896)
- Testing
- Agar-Agar, Agar-Agar and undenatured collagen type II, undenatured collagen type II
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundació Eurecat
Chronic HCV-related Hepatitis
Coffee Effect in HCV-related Hepatitis
Background: In patients with chronic HCV-related liver damage, coffee is associated with a reduced risk of progression and of hepatocellular carcinoma (HCC) development.
- Trial name
- NCT01572103
- Testing
- Coffee, coffee abstinence
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera di Padova
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