Clinical trials: Collagen Diseases
Tendinitis of Shoulder, Hyaluronic Acid
Oral Supplementation Compared With Hyaluronic Acid Infiltration in Rotator Cuff Tendinopathies
The present study aims to investigate the effectiveness of oral supplementation with a nutraceutical containing Collagen, Hyaluronic Acid, Vitamin C, and Manganese in functional outcome and pain reduction in cases of shoulder…
- Conditions
- Tendinitis of Shoulder, Hyaluronic Acid, Dietary Supplements, Shoulder Pain
- Trial name
- NCT06379997
- Testing
- Collagen, Hyaluronic Acid, Vitamin C, and Manganese, Intra-articular infiltration
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Gout, Inflammatory Rheumatism
Treat-to-target by Email During Urate-lowering Therapy in Gout
Gout is secondary to urate crystal deposition after chronic elevation of serum urate level (SUL). Long-term lowering SUL below 360 µmol/L allows dissolution of deposited crystals and disease cure.
- Conditions
- Gout, Inflammatory Rheumatism, Hyperuricemia, Posology Adjustment
- Trial name
- GOUTEmail (NCT04733079)
- Testing
- Cleanweb electronic messaging ePro, Usual follow-up
- Where
- 2 sites in France
- Volunteers
- 204 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Keloid Scar
Proof of Concept (POC) Study of the Soliton's Acoustic Scar Reduction (ASR) Treatment for the Treatment of Keloid Scar
To evaluate the safety, and efficacy of the ASR device for the temporary improvement in the appearance of a keloids.
- Trial name
- ASR (NCT04016610)
- Testing
- Soliton's Acoustic Scar Reduction (SAR)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Soliton
Tendinopathy
Effect of Collagen Supplementation on Tendinopathy
Tendon injuries represent a significant problem in elite athletes. Therefore, prevention and effective treatment of tendon overload injury/tendinopathy is important.
- Trial name
- NCT04578418
- Testing
- Hydrolyzed collagen, Heavy slow resistance training
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Bispebjerg Hospital
Tooth Socket, Dental Implants
Impact of Soft Tissue Grafts on Tissue Alterations After Immediate Tooth Replacement
This study evaluates the impact of soft tissue grafts on soft tissue recession following immediate implant, provisional and bone graft placement in compromised sockets.
- Trial name
- NCT02922075
- Testing
- Connective tissue graft, Collagen matrix graft, Immediate implant
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- São Paulo State University
Systemic Lupus Erythematosus, Idiopathic Juvenile Arthritis
Human Papilloma Virus Vaccination and Chronic Inflammatory Rheumatic Diseases.
Patients with chronic inflammatory rheumatic disease (CIR) are at increased risk for infections. Vaccination is a powerful tool to prevent infections, even in immunocompromised patients.
- Conditions
- Systemic Lupus Erythematosus, Idiopathic Juvenile Arthritis, Human Papilloma Virus
- Trial name
- HPV-CIR (NCT04180228)
- Testing
- self-administred questionnaire
- Where
- 3 sites in France
- Volunteers
- 76 people
- Sponsor
- Hospices Civils de Lyon
Keratoconus, Corneal Ectasia
Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia
This study will determine the efficacy of corneal collagen crosslinking (CXL) combined with Intacs for the treatment of keratoconus and corneal ectasia.
- Trial name
- CXL (NCT01112072)
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Cornea and Laser Eye Institute
Arthritis, Rheumatoid, Spondylitis, Ankylosing
Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory Rheumatism
Autoimmune diseases are the consequence of an abnormality of the immune system, leading it to attack components of our own body. They have a wide variety of presentations.
- Conditions
- Arthritis, Rheumatoid, Spondylitis, Ankylosing, Lupus Erythematosus, Systemic, Scleroderma, Systemic
- Trial name
- MARIGYN (NCT05961267)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 318 people
- Sponsor
- University Hospital, Bordeaux
Diet Habit, Rheumatologic Disease
Rheumatology Diet Study
This study aims to collect information on rheumatology patients' dietary habits, autoimmune disease activity, dietary changes, disease symptom improvements, and perceptions on their dietary habits and how it affects their…
- Conditions
- Diet Habit, Rheumatologic Disease, Autoimmune Diseases, Rheumatoid Arthritis
- Trial name
- NCT06339957
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Central Florida
Keloids, Hypertrophic Scars
Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal Scars
Keloids and hypertrophic scars are a common subject of dermatologic consultations. Therapeutic management of such conditions remains challenging because of their high rate of recurrence and lack of curative treatment.
- Trial name
- NCT01078428
- Testing
- Topical silicone gel, Vaseline
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Skin Condition, Hair Fragility
Assessment of Anti-aging Efficacy of Marine Collagen Peptides
To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
- Conditions
- Skin Condition, Hair Fragility, Nails, Ingrown
- Trial name
- NCT06306105
- Testing
- Marine Collagen Peptides
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Chronic Pain, Musculoskeletal Pain Disorder
Cognitive Bias Modification for Interpretation Individuals With Chronic Musculoskeletal Pain
Cognitive Bias Modification for Interpretation (CBM-I) trains participants to interpret ambiguous information as neutral or benign, rather than interpret it as being related to pain.
- Trial name
- NCT06368362
- Testing
- Benign cognitive bias modification for interpretation, Pain-related cognitive bias modification for interpretation
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Scleroderma, Systemic Sclerosis
The Effect of Physiotherapy Program in Scleroderma Patients
The aim of this study was to investigate the effectiveness of physiotherapy and rehabilitation program on hand involvement of patients with scleroderma and to compare the effects of home rehabilitation program and rehabilitation…
- Conditions
- Scleroderma, Systemic Sclerosis, Hand Rheumatism, Physiotherapy
- Trial name
- NCT04179292
- Testing
- Hand Therapy by Physiotherapist, Hand Therapy as home program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Fibromyalgia
Acupuncture for Fibromyalgia
Fibromyalgia is the second most common autoimmune rheumatic diseases with clinical manifestations of widespread pain, fatigue and accompanied cognitive and emotional disturbances.
- Trial name
- NCT02583334
- Testing
- Verum acupuncture (30# acupuncture needle)
- Where
- 2 sites in Taiwan
- Volunteers
- 158 people
- Sponsor
- China Medical University Hospital
Giant Cell Arteritis
Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis
The standard treatment for Giant Cell arteritis (GCA) is Glucocorticoids(GC), even if GC-related adverse events are commonly occuring. Therefore, other practises for reducing relapses and cumulative GC-doses are needed.
- Trial name
- MTXinGCA (NCT05623592)
- Testing
- Methotrexate, Sodium chloride
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- University of Bonn
Osteogenesis Imperfecta
Results of Telescoping Nail In OI; a Case Series
Assess the postoperative functional outcomes after surgical correction of skeletal deformities of lower limbs in osteogenesis imperfecta patients as regard ambulation status, postoperative complications and reoperation rate.
- Trial name
- NCT04694144
- Testing
- telescoping intramedullary nail
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Assiut University
Gingival Recession
Volume-Stable Collagen Matrix Versus Subepithelial Connective Tissue Graft for Multiple Gingival Recessions
Gingival recession is a clinical condition in which the gingival margin is displaced apically, exposing the root surface. This condition may be associated with esthetic concerns, dentin hypersensitivity, and difficulties in oral…
- Trial name
- VCMX-SCTG (NCT07613775)
- Testing
- Volume-stable xenogeneic collagen matrix (VCMX), Subepithelial connective tissue graft (SCTG)
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Chronic Inflammatory Rheumatism
Catastrophism in Chronic Inflammatory Rheumatism
Catastrophic is defined as a negative cognitive and emotional response based on inadequate pain expression. It has three components: rumination, amplification and vulnerability.
- Trial name
- CRIC (NCT04174092)
- Testing
- completing self-questionnaires
- Where
- 2 sites in France
- Volunteers
- 533 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Gingival Recession
MCAT Versus VISTA With Volume Stable Collagen Matrix in RT3 Gingival Recession
This study aims to compare MCAT technique (supraperiosteal approach with coronal advancement of flap) with VISTA technique(subperiosteal approach with coronal advancement of flap), Further, it may be hypothesized that…
- Trial name
- NCT06433986
- Testing
- Modified Coronally Advanced Tunnel (MCAT)Technique, Vestibular Incision Subperiosteal Tunnel Access (VISTA)Technique
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
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