Clinical trials: Collagen Diseases
Psoriatic Arthritis
Evaluation of Sarcopenia and Related Factors in Patients Diagnosed With Psoriatic Arthritis
The purpose of the study is identify the prevalence of sarcopenia and its associated factors in patients with psoriatic arthritis.
- Trial name
- NCT06437392
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lupus or SLE, Spondyloarthritis
Evaluation of Plasma Vitamin C Levels in a Population of Chronic Rheumatism in Immuno-Rheumatology
Scurvy is an almost forgotten carential pathology, caused by a deep vitamin C (or ascorbic acid) deficiency, a priori exceptional in industrialized countries.
- Trial name
- VitCRIC (NCT05345899)
- Testing
- Evaluation of vitamin C level in plasma, Evaluation of quality of life
- Where
- France
- Volunteers
- 107 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Covid19, Rheumatic Fever
Impact of COVID-19 Pandemic and Social Distancing on Mental Health of Chronic Inflammatory Rheumatism Affected Patients
Recent studies have highlighted the consequences of COVID-19 pandemic and social distancing on mental health of individuals. The aim of this study is to evaluate those consequences within a sample of inflammatory chronic…
- Conditions
- Covid19, Rheumatic Fever, Mental Disorder
- Trial name
- EMOPTION (NCT04798053)
- Testing
- Questionnaire, blood sample and salivary sample
- Where
- 7 sites in France
- Volunteers
- 259 people
- Sponsor
- University Hospital, Bordeaux
Keloid, Scleroderma, Localized
Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix
This research study will evaluate the effectiveness of high dose UVB light therapy in the treatment of keloid (or hypertrophic scar), scleroderma, acne keloidalis nuchae, old burn scars, granuloma annulare or related conditions.
- Conditions
- Keloid, Scleroderma, Localized, Acne Keloidalis, Scars
- Trial name
- NCT00129428
- Testing
- UVB Irradiation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan
Acne Keloidalis Nuchae, AKN
Duobrii Treatment of Acne Keloidalis Nuchae (AKN)
Acne keloidalis nuchae (AKN) is one of the chronic forms of scarring folliculitis, affecting predominantly the occipital scalp, seen mostly in men of African descent.
- Trial name
- NCT05608499
- Testing
- Duobrii, Bryhali
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Skin Condition
Evaluation of Antioxidant and Skin Beauty Effects of Cherry Collagen Drink
To assess cherry collagen drink on skin condition improvement
- Trial name
- NCT05376657
- Testing
- Cherry collagen drink
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Gastrointestinal Disorders
To Assess the Effect of Collagen on Gastrointestinal Discomfort in Healthy Adults With Gastrointestinal Symptoms.
This study will enroll healthy adults with perceived gastrointestinal symptoms to evaluate the effect of collagen peptides compared to placebo.
- Trial name
- NCT06937801
- Testing
- Collagen Peptide
- Where
- Canada
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Rheumatologic Disease
Proof-of-concept Study of 'JIA Toolbox' for Children and Young People (CYP) With Juvenile Idiopathic Arthritis (JIA)
This project aims to further develop and conduct a 'real-world' proof-of-concept assessment of a suite of three products, known as the 'JIA Toolbox', that collectively aim to improve CYP's independence and functional ability 'JIA…
- Trial name
- JIA Toolbox (NCT05563194)
- Testing
- Heating prototype (Prototype 1), Physio tool (Prototype 2), Communication tool (Prototype 3)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Traumatic Brain Injury
Cerebrospinal Fluid Endostatin/Collagen XVIII Concentrations in Patients With Severe Traumatic Brain Injury
Angiogenesis is an important pathophysiological response to traumatic brain injury (TBI) and modulated by pro- and anti-angiogenic factors.
- Trial name
- NCT01846546
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai 6th People's Hospital
Recessive Dystrophic Epidermolysis Bullosa
Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01)
A sub-set of patients who participated in PTR-01-002 will be enrolled in an open-label study, if they meet the study eligibility criteria.
- Trial name
- NCT05143190
- Testing
- PTR-01
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Phoenix Tissue Repair, Inc.
Keloid
The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and Keloids
This study aims to assess the safety and efficacy of Thermo-mechanical system for fractional ablation associated triamcinolone acetonide drug delivery for the treatment of Hypertrophic scars and Keloids.
- Trial name
- NCT04597060
- Testing
- Thermomechanical system with corticosteroids, corticosteroid injection
- Where
- Thailand
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Alport Syndrome Patients With eGFR Between 45-90 ml/Min/1.73 m2
ATHENA: Natural History of Disease Study in Alport Syndrome Patients
There is limited published clinical data about the natural history of renal disease in Alport syndrome. The RG012-01 study will collect data to characterize the progression of renal dysfunction in Alport syndrome patients.
- Trial name
- RG012-01 (NCT02136862)
- Where
- 15 sites in United States, Australia and 4 more
- Volunteers
- 165 people
- Sponsor
- Genzyme, a Sanofi Company
Gingival Recession
Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment
To assess the efficacy of minimally invasive Vestibular Incision Subperiosteal Tunnel Access (VISTA) with collagen membrane and Advanced Platelet-rich Fibrin (A-PRF) in the treatment of multiple buccal gingival recession type…
- Trial name
- NCT06357351
- Testing
- vestibular incision sub periosteal tunnel access ( VISTA) technique.
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss, Gingival Recession
Xenogenic Collagen Matrix vs. Connective Tissue Graft for Soft Tissue Augmentation Around Early Maxillary Implants
This study compares two methods used to improve gingival tissue around dental implants placed in (the maxillary esthetic zone). After a tooth is removed and a dental implant is placed early (usually 4-8 weeks later), additional…
- Conditions
- Alveolar Bone Loss, Gingival Recession, Peri-implant Mucositis
- Trial name
- NCT07024186
- Testing
- Xenogeneic Collagen Matrix, subepithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated
National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry
The goal of this observational study is to develop a registry of Brazilian patients with hereditary cardiovascular diseases, combining clinical and genomic data.
- Conditions
- Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated, Cardiomyopathy Restrictive, Arrhythmogenic Right Ventricular Dysplasia
- Trial name
- RENOMICA-Hcor (NCT06546137)
- Testing
- whole genome sequencing
- Where
- 27 sites in Brazil
- Volunteers
- 1,211 people
- Sponsor
- Hospital do Coracao
Dystrophic Epidermolysis Bullosa
Short Term Observational Study in DEB Patients
The purpose of this study is to better understand disease extent and to identify appropriate methodologies to evaluate (dystrophic epidermolysis bullosa) DEB in a quantitative and qualitative manner.
- Trial name
- NCT02178969
- Where
- 10 sites in United States, Australia and 5 more
- Volunteers
- 29 people
- Sponsor
- Shire
Keratoconus
Standard Corneal Collagen Crosslinking Versus Transepithelial Corneal Crosslinking by Iontophoresis of Riboflavin
The standard CXL technique involves removal of the epithelium to enable riboflavin to penetrate into stromal tissue, to avoid epithelial debridement and increasing the patient's comfort and safety transepithelial corneal…
- Trial name
- NCT02456961
- Testing
- iontophoresis of riboflavin, epithelium-off, Corneal collagen crosslinking
- Volunteers
- 126 people
- Sponsor
- Ufa Eye Research Institute
Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder
Hypermobile Ehlers-Danlos Syndrome - Transcutaneous Auricular Neuromodulation
Investigate whether at-home transcutaneous auricular VNS (tAN: transcutaneous auricular neurostimulation) improves a battery of nine key physical and psychological symptoms of a group of hEDS (Hypermobile Ehlers-Danlos Syndrome…
- Conditions
- Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Ehlers-Danlos Syndrome
- Trial name
- hEDS-tAN (NCT06105541)
- Testing
- Transcutaneous Auricular Neurostimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Keloid
Comparison of Intralesional Triamcinolone Acetonide Treatment With Intralesional Verapamil Hydrochloride in Keloids
The paucity of local literature regarding the comparison of intralesional verapamil with intralesional triamcinolone acetonide led this study to be carried out with the objective of comparing the clinical effectiveness of…
- Trial name
- NCT07420166
- Testing
- Triamcinolone Acetonide, Verapamil Hydrochloride
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Muhammad Aamir Latif
Rheumatoid Arthritis
Safety of FURESTEM-RA Inj. in Patients With Moderate to Severe Rheumatoid Arthritis(RA)
The purpose of phase 1 clinical trial is to to evaluate safety in subjects with moderate to severe rheumatoid arthritis after infusion.
- Trial name
- RA (NCT02221258)
- Testing
- FURESTEM-RA Inj.
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
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