Clinical trials: Colo -Rectal Surgeries
Colo-rectal Cancer, Anesthesia
The Influence of Type of Anesthesia on Postoperative Pain
The investigators designed a multi-center prospective randomized controlled trial to study the influence of the type of anesthesia on postoperative pain after laparoscopic colorectal cancer surgery.
- Trial name
- NCT04239794
- Testing
- Propofol, Sevoflurane
- Where
- 3 sites in South Korea
- Volunteers
- 468 people
- Sponsor
- Seoul National University Hospital
Patient Empowerment, Low Anterior Resection Syndrome
Interactive Online Informational and Peer Support App for Patients with Low Anterior Resection Syndrome
After surgery for rectal cancer, many people undergo changes in bowel habits, which may include the need to empty their bowels more often, accidental leakage of stool or gas, the sudden urge to go to the bathroom, and more.
- Conditions
- Patient Empowerment, Low Anterior Resection Syndrome, Colo-rectal Cancer, Peer Group
- Trial name
- NCT04469426
- Testing
- Interactive online informational and peer support app
- Where
- 5 sites in Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Colo-rectal Surgery, Anastomotic Leak Large Intestine
Comparison of Rates of Anastomotic Leak in Patients Undergoing Colo-rectal Surgery When Bowel Perfusion and Resection Margin is Deterimined by Intra-operative Infra-red Thermography or by Conventional Method
Pilot RCT with 20 patients in both test and control group. In the control group resection \& anastomosis was done using the conventional method.
- Conditions
- Colo-rectal Surgery, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum
- Trial name
- NCT06180564
- Testing
- Intra-operative Infra-red thermography
- Where
- India
- Volunteers
- 43 people
- Sponsor
- Sir Ganga Ram Hospital
Colon Cancer, Frailty
The "SPARCOL" Study
Mortality following elective colorectal cancer surgery range between 2.5-6% and increase for the elderly and frail patient regardless of T-stage.
- Trial name
- NCT05734300
- Testing
- Combined Endoscopic Laparoscopic Surgery (CELS), Standard resection
- Where
- 3 sites in Denmark
- Volunteers
- 48 people
- Sponsor
- Zealand University Hospital
Postoperative Ileus
Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery
The purpose of this trial is to determine whether the water-soluble contrast (gastrografin) is more effective in the treatment of postoperative ileus than the conventional one.
- Trial name
- NCT01440712
- Testing
- Gastrografin, physiological serum
- Where
- 3 sites in Spain
- Volunteers
- 58 people
- Sponsor
- Hospital Universitari de Bellvitge
Colo-rectal Cancer, Colon Cancer
Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic (DECOR-19)
To understand and analyse the global impact of COVID-19 on outpatient services, inpatient care, elective surgery, and perioperative colorectal cancer care, a DElayed COloRectal cancer surgery (DECOR-19) survey was conducted in…
- Conditions
- Colo-rectal Cancer, Colon Cancer, Rectal Cancer, Oncology
- Trial name
- DECOR-19 (NCT04488549)
- Testing
- Survey
- Where
- Italy
- Volunteers
- 1,051 people
- Sponsor
- Treviso Regional Hospital
Minimally Invasive Surgical Procedures, Colo-rectal Cancer
Impact of Obesity on Textbook Outcome Achievement in Minimally Invasive Colorectal Cancer Surgery
Textbook Outcome (TO) is a composite quality measure that integrates multiple perioperative endpoints to provide a comprehensive assessment of surgical quality.
- Trial name
- NCT07756450
- Where
- Turkey (Türkiye)
- Volunteers
- 305 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Colon Cancer
Regional Anesthesia in Colon Rectal Surgery
This study will compare recurrence rates in patients with colorectal cancer who will be randomly assigned to epidural anesthesia/analgesia combined with general anesthesia or to general anesthesia followed by opioid analgesia.
- Trial name
- NCT00684229
- Testing
- Regional anesthesia and analgesia, general anesthesia followed by opioid analgesia
- Where
- 3 sites in United States, Argentina and 1 more
- Sponsor
- The Cleveland Clinic
Colo-rectal Cancer
Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer
NO-CUT is a one-stage phase II trial seeking to establish whether an oxaliplatin-based chemotherapy preceding standard neo-adjuvant fluoropyrimidines-based chemo radiotherapy, can safely spare demolitive surgical intervention in…
- Trial name
- NO-CUT (NCT03565029)
- Testing
- XELOX, Radiotherapy
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Niguarda Hospital
Colo-rectal Cancer, Rectal Prolapse
Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery
Currently a multiport robotic surgery platform (Intuitive Xi) is widely available and used for colorectal surgery indications. A Single port platform (Intuitive SP) is FDA approved for Head and Neck and Urology but has not been…
- Conditions
- Colo-rectal Cancer, Rectal Prolapse, Colostomy Stoma, Colorectal Disorders
- Trial name
- NCT05321134
- Testing
- Single port robotic colorectal surgical procedure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Post-Op Complication, Post Colo- Rectal Surgeries
Core Stability Exercises Versus Tai Chi Exercises on Dynamic Balance After Colo-rectal Surgeries.
Forty patients from both genders, who have undergone colorectal surgeries. Their ages ranged from 25 to 40 years. The participants was selected from El Mataria teaching hospital and randomly distributed into two equal groups.
- Conditions
- Post-Op Complication, Post Colo- Rectal Surgeries, Colo -Rectal Surgeries
- Trial name
- NCT07451444
- Testing
- Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Colo-rectal Anastomosis
Megagon Magnet Anastomosis Plus OTOLoc for Creating Colo-colonic and Colorectal Anastomoses
The primary objective of this trial is to investigate the safety and effectiveness of the Megagon 28.5mm SFM system plus OTOLoc when used to create a colo-colonic and colorectal anastomosis in participants undergoing colon…
- Trial name
- FOCUS II (NCT07856342)
- Testing
- Megagon Self-Forming Magnet
- Volunteers
- 30 people
- Sponsor
- GI Windows, Inc.
Colo-rectal Cancer
EMVI as a Determinant of Metastasis in Colorectal Cancer
Bowel cancer is the fourth most commonly occurring cancer and the second highest cause of cancer deaths in the UK. Despite advances in treatment, over 40% of patients will die within 5 years.
- Trial name
- EVIDENCE (NCT06646341)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Colorectal Cancer
Early Removal of Urinary Catheters in Patients After Rectal Surgery: a Prospective Study
Recent national surgical quality guidelines (Surgical Care Improvement Project, National Hospital Inpatient Quality Measures)state that removal of urinary catheters should occur by post-operative day two for all surgical…
- Trial name
- NCT01186237
- Testing
- Early urinary catheter removal
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stanford University
Colon Cancer, Rectum Cancer
Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas
This study evaluates the safety and performance of SGM-101, a Carcinoembryonic Antigen (CEA)-specific chimeric antibody conjugated with a NIR emitting fluorochrome, for the visualization of CEA-expressing cancers during surgery.
- Conditions
- Colon Cancer, Rectum Cancer, Pancreas Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT02973672
- Testing
- SGM-101
- Where
- 3 sites in Netherlands
- Volunteers
- 75 people
- Sponsor
- Surgimab
Colo-rectal Cancer
A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)
The NSABP FC-13 study is being done to determine if using immunotherapies alone or in combination with other drugs will delay or prevent colorectal cancer from coming back in patients with colorectal cancer who are ctDNA-positive…
- Trial name
- EMPIRE (NCT07058012)
- Testing
- Cemiplimab, cemiplimab plus fianlimab, cemiplimab + REGN7075
- Where
- 13 sites in United States
- Volunteers
- 79 people
- Sponsor
- NSABP Foundation Inc
Colo-rectal Cancer, Colonic Neoplasms Malignant
The Use of Indocyanine Green Near-infrared Fluorescence for Bowel Perfusion Quantitative Assessment in Order to Prevent Anastomotic Leakage in Colorectal Surgery
Anastomotic leakage (AL) is a serious complication after surgery for colon cancer, leading to a significant increase in mortality.Intraoperative fluorescence imaging using indocyanine green has proven to be a feasible and…
- Trial name
- ICG-NIRF (NCT06845306)
- Testing
- ICG-guided bowel perfusion assessment, Conventional Bowel Anastomosis group
- Where
- Russia
- Volunteers
- 1,268 people
- Sponsor
- Vadim Kuznetsov
Colo-rectal Cancer
Psychological distREsS hipEc oR pelVic Exenteration
The purpose of this study is to describe type and extent of psychological distress (adverse effects) in patients undergoing surgery for colorectal cancer with peritoneal metastases and after surgery for colorectal cancer with…
- Trial name
- PRESERVE (NCT04956107)
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 225 people
- Sponsor
- University of Aarhus
Colo-rectal Cancer
Does Omission of NSAIDs After Colorectal Cancer Operation Affect the Consumption of Opioids?
Patients undergoing an operation for colorectal cancer are normally treated with non-steroid-anti-inflammatory-drugs (NSAIDs) e.g. ibuprofen as pain medication after the operation.
- Trial name
- NCT04448652
- Testing
- NSAID
- Where
- Denmark
- Volunteers
- 502 people
- Sponsor
- Zealand University Hospital
Colorectal Neoplasms
Person-Centred Information and Communication for Patients Undergoing Colo-Rectal Surgery - the PINCORE Project
An overarching aim is to create prerequisites for person-centred information and communication. The specific aim is to evaluate if an intervention with a written information and communication support tool and person-centred…
- Trial name
- PINCORE (NCT03587818)
- Testing
- person-centred communication
- Volunteers
- 488 people
- Sponsor
- Göteborg University