Clinical trials: Colon, Sigmoid
Proctitis, Proctosigmoiditis
Efficacy and Safety of Budesonide Foam for Participants With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis
The purpose of this study is to establish the efficacy profile of rectally administered budesonide foam, as compared to an equivalent volume of rectally administered placebo foam over the same dosing schedule, in participants who…
- Trial name
- NCT01008423
- Testing
- Budesonide
- Where
- 62 sites in United States
- Volunteers
- 281 people
- Sponsor
- Bausch Health Americas, Inc.
Incarcerated Inguinal Hernia
Incarcerated Right Inguinal Hernia Containing Sigmoid Colon: An Unusual Case Report
Incarcerated inguinal hernia is an irreducible but the blood supply to the contained part is intact, but developing towards strangulation. Here the lumen of the portion of colon occupying a hernia sac is blocked with faeces.
- Trial name
- NCT05251350
- Testing
- surgery
- Where
- Afghanistan
- Volunteers
- 2,717 people
- Sponsor
- Ahmadullah Danish
Colorectal Neoplasms
Unprepped CT Colonography
It is our objective to improve the performance of CTC in the prepared colon, and to validate CTC in the unprepared colon for the detection of colorectal neoplasia.
- Trial name
- NCT00586053
- Where
- United States
- Volunteers
- 1,255 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diverticulum, Colon, Sigmoid
LASER Trial. LAparoscopic Elective Sigmoid Resection Following divERticulitis - a Multicenter, Prospective, Randomized Clinical Trial
The purpose of this study is to find out whether elective sigmoid resection will improve quality of life compared to conservative treatment with lifestyle guidance and fiber supplement in patients with a recurrent or complicated…
- Trial name
- LASER (NCT02174926)
- Testing
- Elective laparoscopic sigmoid resection, Conservative treatment
- Where
- 11 sites in Finland
- Volunteers
- 133 people
- Sponsor
- Helsinki University Central Hospital
Elderly Patient Withsigmoid Volvulus
Endoscopic Management of Acute Sigmoid Volvulus in High Risk Surgical Eldery Patients: A Randomized Controlled Trial.
This prospective randomized controlled clinical trial included all patients who developed the manifestations of acute a cute sigmoid volvulus and referred to the Zagazig University Hospital Emergency Department between December…
- Trial name
- NCT05620446
- Testing
- endoscopy
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Zagazig University
Sigmoid, Sigmoid Colon, Neoplasm, Cancer
Surgical Anatomy and 'Waisting' of the sIgmoid SpEcimen
Treatment of rectal cancer has improved to the extent that its local recurrence rates are now much lower than other sites in the large bowel.
- Trial name
- WISE (NCT03135808)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Inflammatory Bowel Diseases
Pilot Study for the Evaluation of Food Choices in Patients With Inflammatory Bowel Diseases (MICI2021)
This project is a pilot study exploring the effects of dietary choices and quantitative digestion of gluten ingested by individuals with IBD compared to a control population.
- Trial name
- MICI2021 (NCT05079932)
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Sigmoid Diverticulosis, Colorectal Surgery
Impact of Socioeconomic and Territorial Inequalities on Surgical Management of Sigmoid Diverticulitis
Sigmoid diverticulitis (SD) is a common pathology characterized by inflammation/infection of a diverticulum in the sigmoid colon.
- Trial name
- EDIVERTICULITE (NCT06200857)
- Where
- France
- Volunteers
- 6,800 people
- Sponsor
- University Hospital, Caen
Sigmoid Neoplasms
Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track
A blinded randomized trial. Length of hospital stay, nursing hours and recovery after laparoscopic versus open colonic resection without fast track.
- Trial name
- NCT01127425
- Testing
- laparoscopic colonic resection, laparoscopic sigmoid resection
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Colorectal Anastomosis, Left-sided Colon Resection
Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
The purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter referred to as Signia™ circular stapler) in…
- Conditions
- Colorectal Anastomosis, Left-sided Colon Resection, Anastomotic Leak, Anastomotic Complication
- Trial name
- SECURE (NCT07351071)
- Testing
- Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system)
- Where
- 10 sites in United States
- Volunteers
- 137 people
- Sponsor
- Medtronic - MITG
Intestinal Anastomotic Leak
Risk Factors for Anatomic Leakage in Advanced Ovarian Cancer Surgery
Cytoreductive surgery is currently the main treatment for advanced epithelial ovarian cancer (AEOC), and the complete disease removal (RT=0) or the achievement of an optimal residual disease (RT < 1 cm) remain the factors with…
- Trial name
- NCT04604964
- Testing
- Evaluation of anastomotic leakage occurrence
- Where
- Italy
- Volunteers
- 515 people
- Sponsor
- Catholic University of the Sacred Heart
Colorectal Adenoma
Evaluating the Clinical Value of Transparent Cap-Assisted Second Examination of the Sigmoid Colon for Improving Colorectal Adenoma Detection Rates
A prospective, single-center, single-blind, randomized controlled study to evaluate the clinical value of transparent cap-assisted second examination of the sigmoid colon for improving colorectal adenoma detection rates
- Trial name
- NCT07261319
- Testing
- standard second examination of the sigmoid colon, transparent cap-assisted second examination of the sigmoid colon
- Where
- China
- Volunteers
- 614 people
- Sponsor
- Fudan University
Locally Advanced Pelvic Cancer That Require Pelvic Exenteration
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers
The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic…
- Trial name
- NCT05186493
- Testing
- robot-assisted total pelvic exenteration
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Sigmoid Diseases
Robotic-assisted Versus Laparoscopic Sigmoid Resection
Retrospective multi-center comparative chart review of robotic-assisted versus laparoscopic sigmoid resection for both benign and malignant disease
- Trial name
- NCT02636673
- Testing
- Sigmoid Resection
- Where
- 6 sites in United States
- Volunteers
- 518 people
- Sponsor
- Intuitive Surgical
Mortality, Morbidity
Natural Orifice Specimen Extraction in Sigmoid Volvulus
Sigmoid resection can be performed using conventional and laparoscopic methods. There are few publications in the literature reporting specimen removal from the natural hole in patients with a diagnosis of sigmoid volvulus.
- Trial name
- NCT04740619
- Testing
- Natural Orifice Specimen Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Diverticulitis, Diverticulitis Colon
Management and Evolution of Acute Diverticulitis With Pericolic Free Gas
The severity of diverticulitis is usually graded with the use of modified Hinchey Criteria. However, there is a condition often seen in the CT scan that is not included in this classification itself; 1-2 pericolic bubbles but no…
- Conditions
- Diverticulitis, Diverticulitis Colon, Diverticulitis; Perforation, Bowel, Diverticulitis of Sigmoid
- Trial name
- ADiFas (NCT04311385)
- Testing
- CT imaging
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Central de la Defensa Gómez Ulla
Proctitis, Ulcerative
Efficacy and Safety Study of MAX-002 Suppository Versus Placebo and Active Medicine in Mild to Moderate Ulcerative Proctitis
This is a prospective, multicenter, double-blind (DB), controlled, randomized, parallel group comparison Phase 3a study to evaluate the efficacy and safety of new mesalamine suppositories (MAX-002) as compared to placebo and…
- Trial name
- NCT01016262
- Testing
- MAX-002, Canasa®
- Where
- 40 sites in United States, Canada and 1 more
- Volunteers
- 119 people
- Sponsor
- Forest Laboratories
Distal Radioulnar Joint
Long-term Radiographic and Clinic Outcomes of Ulnar Shortening Osteotomy in Patients With Ulnar Impaction Syndrome and Reverse Oblique Sigmoid Notch
Patients with ulnar impingement are often coexisting with patients with distal ulnar and ulnar joints with a type of sigmoid notch, and ulnar shortening surgery is one of the most useful and long-lasting treatments for the…
- Trial name
- NCT03556527
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Colorectal Cancer, Colorectal Anastomosis
Single-Stapled Technique for Colorectal Anastomosis
The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of…
- Conditions
- Colorectal Cancer, Colorectal Anastomosis, Anastomotic Leakage, Diverticular Disease of Left Side of Colon
- Trial name
- SST (NCT07417358)
- Testing
- Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Colorectal Cancer (CRC), Surgery, Colorectal
Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy
This study is a randomized, controlled trial comparing the short- and long-term outcomes of left colonic artery or first sigmoid artery preservation for rectal surgery.
- Conditions
- Colorectal Cancer (CRC), Surgery, Colorectal, Oncology
- Trial name
- COLAP-D3 (NCT06938490)
- Testing
- Anterior rectal resection with D3-lymphatic dissection
- Where
- Russia
- Volunteers
- 778 people
- Sponsor
- the BELOOSTROV Clinic of High Technologies