Clinical trials: Colon Cancer Screening, open to volunteers
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Colorectal Cancer, Colorectal Adenoma
Early Diagnosis of Colorectal Cancer Based on a Non-invasive Metabolomics Profile
Colorectal cancer is the most frequent tumor in our environment if both sexes are considered together. Every year almost 800 cases are diagnosed in the districts of Tarragona.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Polyp, Healthy
- Trial name
- EarlyCRC (NCT06452745)
- Testing
- Colonoscopy, Urine and FOBT collection
- Where
- 2 sites in Spain
- Volunteers
- 2,000 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Colo-rectal Cancer
Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)
The FIND-CRC study is a prospective collection of samples and data from participants who are at average risk of developing colorectal cancer (CRC).
- Trial name
- FIND-CRC (NCT07046585)
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Colorectal Cancer
Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
Colorectal cancer (CRC) is the third most common cancer in men and the second in women with an incidence of 43,350 new cases in 2018. This incidence is increasing every year. Early detection is crucial in this pathology.
- Trial name
- PREDICT-IRFC (NCT04767568)
- Testing
- Blood sample, Tumor tissue, stool collection
- Where
- 3 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Endometrial Cancer, Lynch Syndrome
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer.
- Conditions
- Endometrial Cancer, Lynch Syndrome, Screening, Early Detection of Cancer
- Trial name
- SCREEN-CUP (NCT07220239)
- Testing
- Menstrual cup use
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jessica D. St. Laurent, MD
Colo-rectal Cancer
Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
The investigators will use a mixed methods study i.e. focus groups involving CHC staff as well as quantitative study which involves analyzing data that is available from the EHR and DRVS population management platform.
- Trial name
- NCT05524428
- Testing
- Implementation Science Strategy
- Where
- 4 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Carcinoma
A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial
This clinical trial studies whether an intervention that addresses two or more levels of care (multilevel intervention) increases follow-up of abnormal, non-invasive, colorectal cancer (CRC) screening test results.
- Trial name
- NCT06822530
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome
A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families
This clinical trial studies whether a web-based program, Kindred, works to improve the understanding of genetic cancer risk and cancer genetic testing in African American families.
- Conditions
- BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome, Hereditary Neoplastic Syndrome, Lynch Syndrome
- Trial name
- NCT07542405
- Testing
- Discussion, Internet-Based Intervention, Survey Administration
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Colorectal Neoplasms, Mass Screening
Preventing Early-Onset Colorectal Cancer in the VA
Colorectal cancer is a leading cause of cancer death among Veterans. The starting age for colorectal cancer screening has been lowered from 50 to 45 years in response to the rising incidence of early-onset colorectal cancer…
- Trial name
- PRECISE (NCT07071454)
- Testing
- Patient intervention, PCP intervention
- Where
- United States
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colon Cancer Screening
Randomized Control Trial Comparing the Incidence of Loop Formation in Colonoscopy Techniques
A colonoscopy is a common procedure used to check for problems in the colon, such as disease or other health issues. Although it's widely used, one challenge is that the flexible tube used in the procedure (called a colonoscope)…
- Trial name
- NCT07245173
- Testing
- colonoscopy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Fecal Immunochemical Test, Colorectal Cancer Screening
Implementation Intention Planning Guide for FIT Colon Cancer Screening
Fecal immunochemical tests (FIT) are a primary method of screening for colorectal cancer (CRC). Implementation intention planning involves encouraging completion or eliminating barriers for the participant to make a plan to…
- Trial name
- NCT07183046
- Testing
- Implementation Intention Guide
- Where
- 5 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colorectal Cancer Screening, Colorectal Cancer (CRC)
Improving Colorectal Cancer Early Screening in Portugal: Identification of Gut Microbiome Biomarkers in Stool (GUTBIOME-PT)
Colorectal cancer (CRC) is a major public health problem, responsible for 2 million new cases and almost 1 million deaths annually worldwide.
- Conditions
- Colorectal Cancer Screening, Colorectal Cancer (CRC), Microbiome
- Trial name
- GUTBIOME-PT (NCT06741293)
- Testing
- No intervention: observational study
- Where
- Portugal
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Gulbenkian Institute for Molecular Medicine
Colorectal Cancer, Advanced Neoplasia
Development and Validation of a Colorectal Cancer Diagnostic Model
This is a multicenter, observational study designed to develop and validate a diagnostic model for colorectal cancer and advanced colorectal neoplasia among adults undergoing routine-care colonoscopy in the Chinese population.
- Conditions
- Colorectal Cancer, Advanced Neoplasia, Prediction Models, Risk Stratification
- Trial name
- NCT07692555
- Where
- 4 sites in China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Lynch Syndrome
Overcoming Barriers to Uptake of Cascade Screening
Lynch syndrome is a genetic condition that increases cancer risk. The public health impact of genetic testing for disease prevention hinges on cascade screening, which is the systematic identification and testing of blood…
- Trial name
- NCT07304063
- Testing
- Let's Talk Genetics Providers, Let's Talk Patients
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colo-rectal Cancer, Shared Decision Making
Shared Decision-Making for Colorectal Cancer Screening in High-Risk First-Degree Relatives Aged 40-49
The primary objective of this study was to evaluate the impact of a constructed shared decision (SDM) intervention (offering an option between colonoscopy and immunochemical collapsible occult blood testing (fecal immunochemical…
- Conditions
- Colo-rectal Cancer, Shared Decision Making, Patient Decision Aid
- Trial name
- NCT07503847
- Testing
- Colonoscopy, Shared Decision-Making
- Where
- Taiwan
- Volunteers
- 2,286 people
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Lynch Syndrome, Colorectal Cancer (CRC)
Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in Vietnam
This study evaluates the predictive value of PREMM5, MMRpredict models, and Universal Tumor Screening in detecting Lynch Syndrome in colorectal cancer (CRC) patients in Vietnam.
- Trial name
- Predict_LS_VN (NCT06863038)
- Where
- Vietnam
- Volunteers
- 572 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Cancer Colon, Cancer, Liver
Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE)
To evaluate the diagnostic performance of blood-based SPOT-MAS test in symptomatic individuals, the investigators sought to launch a prospective multicenter study, named K-ACCELERATE.
- Conditions
- Cancer Colon, Cancer, Liver, Cancer, Lung, Cancer, Breast
- Trial name
- K-ACCELERATE (NCT06391749)
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- Gene Solutions
Screening for Colon Cancer, Survey and Questionnaire
Exploring Participant Preference for Screening Methods and Experience Into Colorectal Cancer Screening Programme
The goal of this low-risk interventional study is to analyze participants' assessment of colorectal cancer screening program through screening method preference and experience after FOBT analysis in screaned participant…
- Trial name
- MS-Care (NCT06696534)
- Testing
- Survey using a questionnaire.
- Where
- 2 sites in Portugal, Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ADVANCED MARKER DISCOVERY S.L.
Colorectal Cancer
SMARTER: Using Blood Samples to iMprove FIT-bAsed coloRecTal cancEr scReening
The project aims to investigate whether colorectal cancer screening can be improved using blood tests, thereby reducing the number of unnecessary colonoscopies.
- Trial name
- NCT06714318
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- Vejle Hospital