Clinical trials: Colon Cleansing
Colon Cleansing
Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing
The purpose of this study is to compare the safety and efficacy of OsmoPrep tablets versus HalfLytely and Bisacodyl Tablet Bowel Prep Kit in subjects who are undergoing colonoscopy.
- Trial name
- NCT01427296
- Testing
- Polyethylene glycol, Oral sodium phosphate solution
- Where
- 18 sites in United States
- Volunteers
- 2,154 people
- Sponsor
- Bausch Health Americas, Inc.
Anal Fistula, Rectal Fistula
Mechanical Bowel Preparation Prior To Sphincter-Sparing Surgery For Complex Anal Fistulae
The goal of this clinical trial is to learn whether bowel preparation with Plenvu before surgery improves healing of complex anal fistula in adults aged 18 to 64 years with a fistula of cryptoglandular origin or associated with…
- Conditions
- Anal Fistula, Rectal Fistula, Crohn Disease
- Trial name
- PLEN-SPARE (NCT07897539)
- Testing
- Mechanical bowel preparation
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Region Skane
Bowel Preparation Before Colonoscopy
A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children
A randomised, single-blind, active controlled, multi-centre trial to evaluate the efficacy, safety, tolerability, acceptability and palatability of PMF104 compared to a conventional PEG-electrolyte solution in paediatric subjects…
- Trial name
- NCT03106922
- Testing
- PMF104, Klean-prep
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 430 people
- Sponsor
- Alfasigma S.p.A.
Colon Disease
A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy
The trial is about comparing the efficacy of Plenvu with Picoprep. Both are bowel cleansing agents prior to visual examination of the large bowel to exclude cancer disease.
- Trial name
- NCT05436054
- Testing
- Picoprep, Plenvu
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aalborg University Hospital
Colorectal Cancer, Colon Polyp
Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy
One tricky aspect of the recommendations for colonoscopy prep is diet. This has a significant impact on the experience of the patient or participant in the screening program and, on the other hand, low adherence has been found in…
- Conditions
- Colorectal Cancer, Colon Polyp, Colon Adenoma
- Trial name
- CriLi (NCT04664543)
- Testing
- Free diet, Three days low residue diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Parc Taulí Hospital Universitari
Diabetes Mellitus, Colonic Diseases
Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients
This trial will compare the tolerance to 2 different methods for colon cleansing before colonoscopy in diabetic patients.
- Trial name
- iDIMEPREP (NCT02297399)
- Testing
- PEG-ascorbate 2L, PEG 4L
- Where
- 2 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Parc de Salut Mar
Colonoscopy
MoviPrep® Versus HalfLytely®, Low-VolUme PEG Solutions for Colon Cleansing: An InvesTigator-blindEd, Randomized, Trial
A properly prepared colon is vital to the success of any colonoscopy. The purpose of this study is to determine which colon prep, MoviPrep or HalfLytely is the superior prepping agent.
- Trial name
- LUSTER (NCT00779649)
- Testing
- MoviPrep Kit, HalfLytely and Bisacodyl Tablets Bowel Prep Kit
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Gastrointestinal Disease, Colorectal Cancer
Evaluation of the Bowel Cleansing in Hospitalized Patients Using Pure-Vu System
The aim of this study is to evaluate the potential improvement in colonoscopy procedure's outcomes when using the Pure-Vu System in hospitalized patients who are indicated for colonoscopy procedure.
- Trial name
- NCT03503162
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Motus GI Medical Technologies Ltd
Colon Adenoma
Risk Factors of Poor Bowel Cleansing in Inpatients
The main purpose of the study is to determine risk factors of poor bowel cleansing in inpatients after a split-dose high volume preparation with 4 liters of polyethylene glycol.
- Trial name
- NCT03902561
- Testing
- one time colonoscopy in inpatients
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Canarias
Colonoscopy Preparation
Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.
The purpose of the study is to assess whether a low volume polyethylene glycol (PEG) plus ascorbic acid based bowel preparation for colonoscopy is not inferior to a large volume polyethylene glycol preparation in subjects with…
- Trial name
- REPREP1 (NCT02073552)
- Testing
- Polyethylene glycol 4000, Macrogol 3350 plus ascorbic acid
- Where
- Spain
- Volunteers
- 472 people
- Sponsor
- Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Colonoscopy
Tolerability, Efficacy and Mucosal Inflammation Associated With Orally Administered Colon Cleansing for Colonoscopy
Colonoscopy is the gold standard investigation for assessing the lining of the colon. Colon cleansing preparations are required to be taken prior to colonoscopy to provide effective visualisation and identification of any…
- Trial name
- NCT00750763
- Testing
- Colonlytely, Picolax/Picoprep, Fleet
- Where
- Australia
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- Fremantle Hospital and Health Service
Bowel Preparation
Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic…
- Trial name
- NCT05137145
- Testing
- Linaclotide, Compound Polyethylene Glycol Electrolyte Powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Colorectal Cancer, Colonic Adenoma
Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
The diagnostic accuracy and safety of colonoscopy highly depends on the quality of the pre-procedural bowel preparation. A past history of poor bowel preparation is the most important risk factor of inadequate bowel cleansing at…
- Conditions
- Colorectal Cancer, Colonic Adenoma, Bowel Preparation
- Trial name
- NCT04700410
- Testing
- Pure-Vu System
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- Radboud University Medical Center
Cleansing Quality of the Colon
Impact of a Predictive Score of Bowel Preparation Quality in Clinical Practice
This is a single center randomized controlled trial to compare the colon cleansing quality determined by the Boston Bowel Preparation Scale achieved by two strategies in patients with high risk of poor colon cleansing defined as…
- Trial name
- REPREP2 (NCT03830489)
- Testing
- polyethylene glycol, polyethylene glycol plus ascorbic acid
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital Universitario de Canarias
Colon Cancer
The Effect of Mentholyptus Drops on the Palatability of PEG-Electrolyte Solution
The investigators aim is to study the efficacy of mentholyptus drops in improving the palatability of PEG-electrolyte solution used in bowel cleansing for colonoscopy.
- Trial name
- NCT01541683
- Testing
- PEG solution (Fortrans®) and Mentholyptus Drops (Halls®), PEG solution (Fortrans®)
- Where
- Lebanon
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colon Cancer
Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening Colonoscopy
A study to assess the pharmacodynamics, safety and tolerability of a PEG-based bowel cleansing solution (MOVIPREP®)
- Trial name
- NCT01714466
- Testing
- NER1006, MOVIPREP
- Where
- 2 sites in Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Norgine
Need for Bowel Preparation
Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy
To study the efficacy and safety of Prepopik® in children aged 9 to 16 years for overall colon cleansing in preparation of colonoscopy
- Trial name
- Prepopik PREA (NCT01928862)
- Testing
- Prepopik® ½ Sachet x 2 (9-12 years), Prepopik® 1 Sachet x 2 (9-12 years), Oral polyethylene glycol (PEG) based preparation (9-12 years)
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ferring Pharmaceuticals
Cleansing Quality of the Colon
Patient and Colonoscopy Cleansing Quality Agreement
The main purpose of the study is to determine the agreement between colon cleansing quality assessed by a validated scale (Boston Bowel Preparation Scale, BBPS) and the perception of the patient.
- Trial name
- CALPER (NCT04702646)
- Testing
- Bowel preparation before colonoscopy, Colonoscopy
- Where
- Spain
- Volunteers
- 1,011 people
- Sponsor
- Hospital Universitario de Canarias
Colon Adenoma
Predictors of Poor Bowel Cleansing and Capsule Endoscopy (CEPREDICT)
The main purpose of the study is to determine risk factors of poor bowel cleansing in patients referred for colon capsule endoscopy (CCE) examination.
- Trial name
- CEPREDICT (NCT03933371)
- Testing
- Colon Capsule Endoscopy
- Volunteers
- 403 people
- Sponsor
- Hospital Universitario de Canarias