Clinical trials: Colonoscopy
Polyps
Carbon Dioxide During Screening Unsedated Colonoscopy
Colonoscopy is currently most effective procedure used for detecting colon cancer especially in the early stages. Screening colonoscopies are performed in the symptom-free patients at risk of familial colon cancer.
- Trial name
- NCT01461564
- Testing
- Colonoscopy
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Patient Satisfaction and Efficacy of Bowel-preparation, Colon Cancer Prevention
Effectiveness of Nurse Tele-consultation on the Quality of Elective Colonoscopy, Procedure-related Anxiety, and Financial Toxicity
This is a multicenter, non-pharmacological, experimental, prospective, randomized study, with two arms (1:1) in a single-blind design.
- Trial name
- NCT06887244
- Testing
- Tele-consultation
- Where
- Italy
- Volunteers
- 534 people
- Sponsor
- National Cancer Institute, Naples
AI-assisted Colonoscopy
AI_Colonoscopy_for_Fellows
The goal of this study is to look at how good artificial intelligence (AI) assisted colonoscopy is compared to conventional colonoscopy in detecting polyps when used by gastroenterology fellows.
- Trial name
- NCT07661914
- Testing
- AI assisted colonoscopy, Conventional Colonoscopy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Colon Cancer Screening
Colonoscopy Bowel Prep Comparison Among Diabetic Patients
The goal of this clinical trial is to learn if the Golytely or SUPREP bowel preparation works more effectively in bowel cleansing for colorectal cancer screening with colonoscopy in patients with diabetes.
- Trial name
- NCT07351019
- Testing
- Golytely, SUPRPEP
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eisenhower Army Medical Center
Adenomatous Polyp of Colon
The Utility of Time Segmental Withdrawal During Screening Colonoscopy for Increasing Adenoma Detection Rate.
Colonoscopy( examining the colon with a flexible tube and a camera ) is usually done for screening purposes to find any precancerous lesions (polyps) at an early stage.
- Trial name
- NCT02538406
- Testing
- Segmental withdrawal
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Baylor College of Medicine
Colonoscopy, Colonic Polyp
Effect of Chewing Gum and WeChat Enhanced Instructions on the Bowel Preparation Quality in Patients With Constipation
Patients with constipation are more likely to have poor bowel preparation quality due to slow gut motility and poor emptying ability. Gum chewing, as a proxy of sham feeding, is a very simple way used to accelerate gut motility.
- Conditions
- Colonoscopy, Colonic Polyp, Constipation
- Trial name
- NCT05447403
- Testing
- Chewing gum combined with WeChat enhanced instructions
- Where
- China
- Volunteers
- 115 people
- Sponsor
- General Hospital of Shenyang Military Region
Colonic Diseases
Intravenous Saline Pre-hydration in Patients Undergoing Outpatient Colonoscopy
Colonoscopy and sedation are frequently accompanied by hypotension, which reduces the amount of sedation able to be employed. Blood pressure is restored by the infusion of intravenous normal saline.
- Trial name
- NCT00308152
- Testing
- Infusion of 1 litre of normal saline before colonoscopy
- Where
- Australia
- Volunteers
- 1,000 people
- Sponsor
- The Canberra Hospital
Colorectal Cancer
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75.
- Trial name
- SCORE (NCT04406714)
- Testing
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Where
- 2 sites in United States
- Volunteers
- 4,318 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colon Cancer, IBS
Patient Satisfaction With Propofol for Out Patient Colonoscopy
The primary purpose of this study is to determine if patient satisfaction with propofol is better than with non-propofol anesthesia for outpatient colonoscopies.
- Conditions
- Colon Cancer, IBS, Polyps
- Trial name
- NCT02937506
- Testing
- Propofol, Fentanyl Plus Midazolam
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Colonoscopy
BLI800-303: An Efficacy Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To evaluate the safety and efficacy of BLI800 vs an FDA approved bowel preparation before colonoscopic examination in adult subjects.
- Trial name
- NCT00856843
- Testing
- BLI800, Polyethylene glycol 3350 based bowel preparation
- Where
- 5 sites in United States
- Volunteers
- 136 people
- Sponsor
- Braintree Laboratories
Colonoscopy, Bowel Cleansing
The Effect of pH Value of Water Consumed During Bowel Preparation Before Colonoscopy on Colon Cleansing
Colonoscopy is a commonly used minimally invasive method for evaluating the lower gastrointestinal tract. The quality of colonoscopy is assessed by factors such as cecal intubation rate and adenoma detection rate, both of which…
- Conditions
- Colonoscopy, Bowel Cleansing, Water Intake, pH
- Trial name
- NCT07669116
- Testing
- Colon preparation for colonoscopy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sinan Ömeroğlu, MD
Bowel Preparation
A Phase 3 Clinical Trials for Bowel Preparation for Colonoscopy
A prospective randomized study compared to the active control. Researchers compare colon cleansing in patients undergoing colonoscopy
- Trial name
- NCT06287606
- Testing
- CTP0302-A, CTP0302-B, Conventional OST
- Where
- South Korea
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Colorectal Cancer
Safety & Effectiveness of Nurse Performed Colonoscopies Under Supervision
There is no theoretical or practical reason why non-medical personnel such as nurses could not be trained to perform diagnostic colonoscopy with comparable proficiency as medical endoscopists.
- Trial name
- NCT01923155
- Testing
- Colonoscopy
- Where
- Hong Kong
- Volunteers
- 731 people
- Sponsor
- Chinese University of Hong Kong
Ulcerative Colitis, Colonoscopy
Ulcerative Colitis Mayo Score With Artificial Intelligence
This project will use deep learning to classify colonoscopy images of different severity of ulcerative colitis, so as to assist clinicians in the accurate diagnosis of ulcerative colitis.
- Conditions
- Ulcerative Colitis, Colonoscopy, Deep Learning
- Trial name
- NCT05336773
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Polyp, Adenomatous Polyp
Endoscopy Nurse Participation in Adenoma Detection Rate During Colonoscopy
Colorectal cancer (CRC) is the second most common cancer and the fourth leading cause of cancer death in Korea. Colonoscopy with polypectomy decreases the incidence and mortality from colorectal cancer.
- Conditions
- Polyp, Adenomatous Polyp, Colonoscopy
- Trial name
- NCT01124266
- Testing
- standard of care colonoscopy
- Where
- 6 sites in South Korea
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Soon Chun Hyang University
Patient Satisfaction and Efficacy of Bowel-preparation
Patient Satisfaction and Efficacy of Different PEG-based Bowel Preparations- an Observational Study
An multi-center, observational study where we compare the current standard, PEG-based bowel-prep to a (in Sweden) recently approved and introduced low volume (1 litre) PEG-based bowel-prep (Plenvu) in a clinical routine…
- Trial name
- NCT05192551
- Testing
- Bowel-prep (Plenvu as experimental arm)
- Where
- 5 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Colonic Adenomas
Soft Coagulation for the Prevention of Adenoma Recurrence
Recurrence after endoscopic mucosal resection of laterally spreading lesions (LSL) >= 20mm in size occurs in approximately 20% of cases at surveillance colonoscopy.
- Trial name
- SCAR (NCT01789749)
- Testing
- Snare Tip Soft Coagulation, No Snare Tip Soft Coagulation
- Where
- 4 sites in Australia
- Volunteers
- 455 people
- Sponsor
- Professor Michael Bourke
Colon Cancer Screening
Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy
Colorectal cancer is the second leading cause of cancer deaths that could be prevented in the United States. Colonoscopy is the best test for finding and removing polyps before they turn into cancer.
- Trial name
- NCT07320989
- Testing
- Chewing Sugar-Free Gum During Bowel Preparation, Standard Bowel Prep (2L PEG-ELP), Standard Bowel Prep
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Crohn's Disease
Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease
Prospective study to compare in a blinded fashion four different diagnostic modalities to detect active small bowel Crohn's disease: a) colonoscopy with ileoscopy; b) small bowel follow through; c) capsule endoscopy; and d)…
- Trial name
- NCT00588653
- Testing
- Capsule endoscopy, CT enterography, colonoscopy, small bowel follow-through
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Bowel Preparation
Impact of Artificial Intelligence-based Patient Reinforcement on Quality of Colonoscopy
In order to improve bowel preparation for colonoscopy and consequently enhance detection rate of malignant and premalignant findings, a prospective, randomized and controlled three-arm study was developed.
- Trial name
- ARCHES (NCT05041283)
- Testing
- Chatbot, Phone call
- Where
- 3 sites in Germany
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- University of Ulm