Clinical trials: Colonoscopy
Cathartics, Mobile Applications
Improving Bowel Cleansing With a Smart Phone Application
Getting ready for a colonoscopy is difficult and involves a lot of steps. The information given to patients is very important to adherence to treatment.
- Trial name
- NCT02303743
- Testing
- Smart Phone Application, Written instructions with visual aids
- Volunteers
- 260 people
- Sponsor
- Vicente Lorenzo-Zúñiga García
Colonoscopy
Cap-assisted Water Immersion Versus Water Immersion Colonoscopy
Water immersion insertion has been documented to decrease procedure-related discomfort during colonoscopy. Cap attached to the colonoscope tip may improve insertion and shorten cecal intubation time.
- Trial name
- NCT01547247
- Testing
- soft straight distal cap D-201-14304 Olympus attached to the tip of the colonoscope, water immersion colonoscopy
- Where
- Czechia
- Volunteers
- 208 people
- Sponsor
- Vitkovice Hospital
Colorectal Cancer
The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy
Evaluation of the histologically proven adenoma and carcinoma detection rate in patients undergoing a full colonoscopy with and without mucosal contrast enhancement, obtained with 200 mg of Methylene Blue MMX® tablets.
- Trial name
- NCT01694966
- Testing
- Methylene Blue MMX®
- Where
- 19 sites in United States, Belgium and 6 more
- Volunteers
- 1,249 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Diverticulosis
Evaluate the Safety and Diagnostic Advantages of Tilt Down Verses Standard Horizontal Colonoscopy Positioning
A tortuous sigmoid colon makes colonoscopy difficult. The purpose of this study was to systematically evaluate the diagnostic utility and incidence of adverse events in women using standard horizontal compared to lateral tilt…
- Trial name
- CTDTTIE (NCT01815671)
- Testing
- colonoscopy in the lateral horizontal position
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Specialists in Gastroenterology, LLC
Colonoscopy, Oxygenation
Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy
Nasal continuous positive airway pressure (nCPAP) has been shown to effectively relieve upper airway obstruction in patients with OSA as it creates a pneumatic stent in the hypopharynx that reduces obstruction and allows for…
- Conditions
- Colonoscopy, Oxygenation, Ventilation
- Trial name
- NCT03139448
- Testing
- Oxygen via nasal cannula, Oxygen via SuperNO2VA nasal mask
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Vanderbilt University Medical Center
Colonoscopy, Bowel Preparation
An Open Label Study to Assess the Effect of BLI800 on Safety and Clinical Chemistry Parameters
To evaluate and compare the effects on safety measures and clinical chemistry after BLI800 in two groups of patients and one group of healthy controls.
- Trial name
- NCT00583713
- Testing
- BLI-800
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Braintree Laboratories
Colonoscopy, Endoscopy, Digestive System
Safety and Effectiveness of a Computer-Assisted Personalized Sedation (CAPS) Device for Propofol Delivery During Endoscopy
Patients routinely receive sedation during a colonoscopy or upper endoscopy (esophagogastroduodenoscopy; EGD) procedure. Propofol is a sedative that can be used during these procedures.
- Conditions
- Colonoscopy, Endoscopy, Digestive System, Conscious Sedation
- Trial name
- NCT00452426
- Testing
- Computer-Assisted Personalized Sedation (CAPS) Device (SEDASYS® System), benzodiazepines and opioid sedation
- Where
- 7 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Ethicon Endo-Surgery
Clostridium Difficile Infection Recurrence
A Multi-center, Single-arm Trial Exploring the Safety and Clinical Effectiveness of RBX2660 Administered by Colonoscopy to Adults With Recurrent Clostridioides Difficile Infection
This trial will be initiated to explore whether RBX2660 (REBYOTA®) could be suitable for administration by the practice of colonoscopy.
- Trial name
- CDI-SCOPE (NCT05831189)
- Testing
- RBX2660
- Where
- 12 sites in United States
- Volunteers
- 41 people
- Sponsor
- Ferring Pharmaceuticals
Polyp, Colorectal
Colorectal Polyp Clinical Decision Support Device Study
The study objective is to establish the efficacy of the colorectal polyp Clinical Decision Support Device (CDSD) in clinical use.
- Conditions
- Polyp, Colorectal, Colonoscopy
- Trial name
- CDSD (NCT04437615)
- Testing
- Colonoscopy, Clinical Decision Support Device
- Where
- United States
- Volunteers
- 2,379 people
- Sponsor
- Olympus Corporation of the Americas
Colorectal Neoplasms
Internet-Based Motivational Interviewing for Colonoscopy
Compared to other racial groups, African Americans have the highest colorectal cancer (CRC) morbidity and mortality rates. Although colonoscopies can prevent CRC, nearly one third of African Americans have not received a…
- Trial name
- NCT03595904
- Testing
- E-Motivate group, Usual Care Group
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colonic Neoplasms
Yoga and Bolus Lukewarm Saline as Rapid Colonoscopy Preparation
A quality colonoscopy examination remains as the gold standard for colorectal cancer screening, but effective large bowel cleansing prior to colonoscopy is still not achieved in all cases that undergo the procedure.
- Trial name
- NCT01547130
- Testing
- Normal (0.9%) saline, HalfLytely
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Arya, Vijaypal, M.D., P.C.
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colorectal Neoplasms
Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System
High quality screening colonoscopy is critical for colorectal cancer (CRC) prevention in Veterans. There is significant variability in colonoscopy quality in VA that is directly linked to differences in CRC incidence and death.
- Trial name
- NCT04389957
- Testing
- Veterans Affairs Endoscopy Quality Improvement Program (VA-EQuIP)
- Where
- 6 sites in United States
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Performance and Tolerance of Colonoscopy
Effectiveness of Abdominal Binder Use During Colonoscopy
Colonoscopy is considered the primary screening test for colorectal cancer screening worldwide. For technical difficulties previously experienced during colonoscopy, especially loop of the colonoscopy device in the colon, many…
- Trial name
- NCT04383132
- Testing
- Abdominal Binder
- Where
- Turkey (Türkiye)
- Volunteers
- 346 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
CRC
Evaluation of the Motus GI CleanUp System During Screening Colonoscopy
Motus GI is developing a single-use device that attaches to a standard colonoscope, thereby integrating colon cleansing, screening and treatment into one procedure. The device creates turbulence within the colon using water jets.
- Trial name
- NCT01838980
- Testing
- Motus GI Clean-Up Device
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Sedation, Endoscopy
Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing Colonoscopy
Patients who are undergoing colonoscopy and are not adequately sedated after initial standard sedation with midazolam 5 mg and fentanyl 100 mcg will be randomly assigned to receive diphenhydramine vs.
- Trial name
- NCT01769586
- Testing
- Diphenhydramine, Midazolam
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- VA Connecticut Healthcare System
Colorectal Cancer Screening
Bowel Preparation in Colonoscopy: Lactulose vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study.
The goal of this clinical trial it is to bowel the instestinal preparation with lactulose vs poliethylenglicol as better agent to have a quality colonoscopy and demostrate that lactulose is most efective, has a good tolerance and…
- Trial name
- NCT06666556
- Testing
- Bowel preparation before colonoscopy
- Where
- 3 sites in Mexico
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Ulcerative Colitis
Neoplasia Detection With Methylene Blue MMX Tablets in Patients With UC Undergoing Colonoscopy
Evaluation of the intraepithelial neoplasia detection rate in patients with long standing ulcerative colitis undergoing mucosal staining with oral methylene blue MMX tablets prior to colonoscopy.
- Trial name
- NCT01520324
- Testing
- oral delivery mucosal stain
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- Cosmo Technologies Ltd
Colonoscopy
A Safety and Efficacy Comparison of BLI4700 Bowel Prep Versus an FDA-approved Comparator in Adults Prior to Colonoscopy
The objective of this study is to compare the safety and efficacy of BLI4700 bowel preparation to an FDA-approved bowel preparation as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT03404401
- Testing
- BLI4700, Polyethylene glycol bowel preparation
- Where
- 23 sites in United States
- Volunteers
- 620 people
- Sponsor
- Braintree Laboratories
Spinal Cord Injury
Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
The annual incidence of colorectal cancer in the US during 2005 was approximately 150,000 cases and this neoplasm claimed 56,000 lives (American Cancer Society).
- Trial name
- NCT00745095
- Testing
- Neostigmine
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs