Clinical trials: Colonoscopy Pain
Adenoma, Pain
Water Method in Elder Patients With Unsedated Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Trial name
- NCT01546220
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Pain, Colorectal Adenomas
Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy
Insufflation of the colon, usually with room air, is necessary to distend the lumen for exploration. Carbon dioxide (CO2) insufflation instead of room air insufflation (AI) has been shown to decrease symptoms of abdominal pain or…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01954862
- Testing
- Air Insufflation method., CO2 insufflation, Water Immersion/CO2
- Where
- 3 sites in United States, Czechia and 1 more
- Volunteers
- 624 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Colonoscopy, Unsedated
Factors Associated With Pain During Unsedated Colonoscopy
Colonoscopy is the gold standard in the diagnosis and treatment colorectal disease, but due to the uncomfortable or even painful procedure, a part of people unwilling to undergoing the examination and giving analgesic agents were…
- Conditions
- Colonoscopy, Unsedated, Pain
- Trial name
- NCT03420612
- Where
- China
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Pain, Satisfaction
Randomized Controlled Trial Comparing Co2 vs. Air in Colonoscopy in Sedated Patients
CO2 insufflation instead of air for colonic distension in colonoscopy is considered to reduce pain after and during colonoscopy. There is limited data, that Co2 is similar effective in sedated patients.
- Trial name
- NCT00660296
- Testing
- Air insufflation use in colonoscopy, CO2 use in colonoscopy
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Vienna
Colorectal Cancer, Colorectal Adenomas
Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening
The degree of protection afforded by colonoscopy against proximal colorectal cancer (CRC) appears to be related to the quality of the procedure, and the incomplete removal of lesions has been shown to increase the subsequent risk…
- Conditions
- Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
- Trial name
- NCT02041507
- Testing
- Air insufflation method., Water Immersion method., Water Exchange method.
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 1,224 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Intubation, Surgery
Water Method Colonoscopy in Patients With Prior Surgery
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Conditions
- Intubation, Surgery, Adenoma, Pain
- Trial name
- NCT01485133
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Air Force Military Medical University, China
Colonoscopy, Pain
Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients
Colonoscopy is generally considered an invasive procedure that causes remarkable pain to the patient. The pain associated with the procedure is not caused by the insertion of the scope but from inflating of the colon in order to…
- Trial name
- Abstral (NCT01604187)
- Testing
- Fentanyl
- Where
- Finland
- Volunteers
- 158 people
- Sponsor
- Turku University Hospital
Pain
Electrical Stimulation Over Acupuncture Points in Reduction of Rectal Discomfort Distension
Colonoscopy is a stressful and unpleasant procedure especially during the passage of the endoscope through angulations of colon. Electro-acupuncture is one of the alternative to reduce colorectal discomfort.
- Trial name
- NCT01551654
- Testing
- Transcutaneous Electrical Nerve Stimulation (ITO Company )
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pain
Acu-TENS for Pain Relief During Colonoscopy
Background: Colonoscopy is often regarded as a painful and unpleasant procedure. Transcutaneous Electric Nerve Stimulation on Acupoints (Acu-TENS) is a non-invasive modality that has been used successfully to treat pain of…
- Trial name
- NCT01751815
- Testing
- Acu-TENS
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Chinese University of Hong Kong
Pain
Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation
The purpose of this study is to determine whether ketamine, midazolam, and meperidine are more effective than midazolam and meperidine alone for procedural sedation and analgesia in pediatric digestive endoscopy.
- Trial name
- NCT01168492
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Université de Montréal
Colonoscopy
The Effect of Virtual Reality Application on Pain, Anxiety, and Embarrassment During Colonoscopy
This study will be conducted to determine the effects of virtual reality (VR) intervention applied during colonoscopy performed without sedation on pain, anxiety, embarrassment, and physiological parameters.
- Trial name
- COLONOSCOPY (NCT07853300)
- Testing
- Virtual Reality (VR) Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Pain
Use of Binaural Beats for Colonoscopy
Investigators verify the effectiveness of "binaural beats" to reduce pain during colonoscopy .
- Trial name
- NCT04372511
- Testing
- Binaural Beats
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Pain, Cancer
A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy
GIC-1001 is a novel, orally-administered, colonic analgesic drug developed as an alternative to i.v. sedation during full colonoscopy.
- Conditions
- Pain, Cancer, Colonic Diseases
- Trial name
- NCT01926444
- Testing
- GIC-1001
- Where
- 15 sites in United States, Canada
- Volunteers
- 308 people
- Sponsor
- gicare Pharma Inc.
Polyp, Pain
Left-colon WEC May Reduce Insertion Time Compared With Whole-colon WEC.
In most of situation, left colon (especially SD junction) is considered the most difficult part of colonoscopy, where endoscopist may encounter difficulty for scope insertion and patients may feel pain or uncomfortable.
- Trial name
- NCT01735266
- Testing
- Air colonoscopy, Water exchange colonoscopy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Air Force Military Medical University, China
Pain, Colorectal Adenomas
A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening
Water-aided method for colonoscopy can be broadly subdivided into two major categories. Water Immersion (WI), characterized by suction removal of the infused water predominantly during the withdrawal phase of colonoscopy, and…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01780818
- Testing
- Air Insufflation method., Water Immersion method., Water Exchange method.
- Where
- 3 sites in United States, Italy
- Volunteers
- 288 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Abdominal Pain, Diarrhea
The Clinical Application of MCCES in Examination of Human Colon
This study is to determine the feasibility and safety of magnetic-controlled capsule endoscopy system in examination of human colon under the real time monitoring by colonoscopy in the clinical application.
- Conditions
- Abdominal Pain, Diarrhea, Hematochezia
- Trial name
- NCT02536144
- Testing
- magnetic-controlled capsule endoscopy system, Colonoscopy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Virtual Reality, Augmented Reality
Virtual Reality to Reduce Pre-Operative Anxiety
This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing various procedures in the Ambulatory Surgery Center (ASC) at CHLA, as…
- Conditions
- Virtual Reality, Augmented Reality, IV Stick, Mask Induction
- Trial name
- NCT04268914
- Testing
- Oculus Go VR, Mira Prism VR
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Pain
Routine or On-demand Fentanyl in Colonoscopy
Colonoscopy may be an unpleasant procedure. Sedation and/or analgesics is therefore routinely administered in most countries. In Norway, however, routine sedation is rare, and medication is normally given on demand, that is, if…
- Trial name
- FEKOL (NCT01786434)
- Testing
- Routine medication arm, Fentanyl on-demand arm
- Where
- Norway
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Pain
Reduction of Pain in Colonoscopy - Loop First Versus Last
Colonoscopy is an endoscopic examination of the colon. Colonoscopy is used to investigate medical gastroenterological diseases, as well as to investigate suspected cancer and to prevent it by identifying and removing premalignant…
- Trial name
- NCT06521658
- Testing
- Timing of retroflexion
- Where
- 2 sites in Denmark
- Volunteers
- 1,120 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Colonic Diseases
Effect of Magnetic Endoscopic Imaging on Patient Pain During Colonoscopy
Colonoscopy is widely considered as the main choice for patients with suspected colorectal disease,and for screening those at high risk of colorectal cancer.
- Trial name
- NCT02681692
- Testing
- Magnetic endoscopic imaging system
- Where
- China
- Volunteers
- 594 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine