Clinical trials: Colonoscopy Procedure
Colon Adenoma
Linked Color Imaging Versus Narrow Band Imaging for Colorectal Adenoma Detection
This is a prospective randomized trial comparing the adenoma detection rate of LCI with NBI. Eligible patients are randomly allocated in a 1:1 ratio to undergo tandem colonoscopy with LCI (LCI group) or NBI (NBI group).
- Trial name
- NCT03336359
- Testing
- Tandem colonoscopy
- Where
- China
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colonoscopy
Impact of Digital Tools on the Quality of Bowel Preparation for Colonoscopy
This is a single blinded randomized controlled study. The main question of this study is whether better preparation by making full use of digital tools can increase patient compliance with the preparation methods for colonoscopy…
- Trial name
- NCT05734079
- Testing
- Standard of care, Standard of care + Video call, Standard of care + Video call + Educational video film
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Hyponatremia
Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS
Objective: To compare the incidence of peri-colonoscopy hyponatremia associated with PEG 3350 + sports drink (PEG-SD) versus PEG 3350-electrolyte solution + sodium sulfate + sodium ascorbate and ascorbic acid (PEG-ELS).
- Trial name
- NCT01299779
- Testing
- PEG-SD, PEG-ELS
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Thomas Jefferson University
Colonoscopy
Impact of Visualisation an Explanatory Video on the Quality of Bowel Preparation
The research hypothesis is that video visualization improves the quality of bowel preparation and the patients' understanding of the modalities of bowel preparation.
- Trial name
- NCT04475146
- Testing
- video vizualisation
- Where
- 2 sites in France
- Volunteers
- 282 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Melena Due to Gastrointestinal Hemorrhage
The Role of Push Enteroscopy in Patients With Passing Melena With Nondiagnostic EGD.
Melena is often caused by upper gastrointestinal (GI) bleeding; therefore, esophagogastroduodenoscopy (EGD) is the first preferred diagnostic tool. However, EGD fails to identify the bleeding source in about 25% of cases.
- Trial name
- NCT06574542
- Testing
- Push enteroscopy (PE), Colonoscopy
- Where
- Thailand
- Volunteers
- 77 people
- Sponsor
- Mahidol University
Colorectal Screening
Demonstrating Effective Salvage of Inadequate Colonoscopies
The aim of this study is to demonstrate that the use of the Pure-Vu EVS System can salvage inadequately prepared optical colonoscopies (OCs) to adequate OCs.
- Trial name
- NCT05585879
- Testing
- Pure-Vu EVS
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection.
- Trial name
- NCT03845933
- Testing
- Colon polypectomy
- Where
- Taiwan
- Volunteers
- 262 people
- Sponsor
- Evergreen General Hospital, Taiwan
Ulcerative Colitis
Interferon-beta1a (AVONEX) Treatment of Ulcerative Colitis
This study will evaluate the safety and effectiveness of the drug interferon-beta1a (AVONEX) in treating ulcerative colitis and examine the drug's effect on the immune system.
- Trial name
- NCT00048347
- Testing
- AVONEX
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Colonoscopy, Colorectal Cancer Screening
Effect of Counseling and Education on Mechanical Bowel Preparation
The goal of this clinical trial is to learn whether enhanced education and counseling can improve bowel preparation before colonoscopy in high-risk patients.
- Trial name
- EEFEC-AMBP (NCT07093099)
- Testing
- Enhanced Education Package for Bowel Preparation, Standard Education Leaflet
- Where
- Palestinian Territories
- Volunteers
- 150 people
- Sponsor
- Al-Ram Drug Store
Pain
Use of Binaural Beats for Colonoscopy
Investigators verify the effectiveness of "binaural beats" to reduce pain during colonoscopy .
- Trial name
- NCT04372511
- Testing
- Binaural Beats
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Acute Kidney Injury
Renal Safety of Bowel Preparation With Polyethylene Glycol
This study evaluates the changes of renal function after taking bowel cleansing agent polyethylene glycol for elective colonoscopy.
- Trial name
- NCT02657564
- Testing
- Polyethylene glycol (PEG)
- Where
- Taiwan
- Volunteers
- 1,237 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colonic Adenoma, Colonoscopy
Blue Laser Imaging and White Light Imaging Colonic Polyps
The adenoma detection rate by colonoscopy for asymptomatic individuals aged 50 years and older is estimated to be at least 25%. It is known that during colonoscopy, lesions may be missed.
- Trial name
- NCT03421600
- Testing
- blue laser imaging, White light imaging
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Changi General Hospital
Colon Cancer
Augmentation of Screening Colonoscopy With Fecal Immunochemical Testing
The study will determine if adding fecal immunochemical testing (FIT) at yearly intervals to a colonoscopy screening program will improve colon cancer detection rates.
- Trial name
- ASC-FIT (NCT00892593)
- Testing
- Fecal Immunochemical Testing
- Where
- 3 sites in United States
- Volunteers
- 4,100 people
- Sponsor
- Forsyth Medical Center
Clostridium Difficile
Fecal Microbiota Transplantation by Colonoscopy for Recurrent C. Difficile Infection
In the recent past, a deep change in the epidemiology of C. difficile infection has occurred, with a rise in its frequency, severity, and mortality.
- Trial name
- NCT02148601
- Testing
- Fecal Microbiota Transplantation, Standard Antibiotic Therapy, Vancomycin (before randomization)
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Catholic University of the Sacred Heart
Colorectal Neoplasms
Endoangel Withdrawal Overspeed Analysis
Exploring the relationship between the percentage of overspeed of colonoscopy withdrawal and the rate of adenoma detection.
- Trial name
- NCT05069571
- Testing
- Endoangel
- Where
- China
- Volunteers
- 1,210 people
- Sponsor
- Renmin Hospital of Wuhan University
Colonic Adenomatous Polyps
Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon
Colonoscopy has become the "gold standard" in detection of colonic polyps and colon cancer. However, colonoscopy causes significant abdominal discomfort and abdominal pain during and after the procedure, requiring intravenous…
- Trial name
- NCT02117232
- Testing
- Visualization balloon, Traditional CO2 insufflation colonoscopy
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Colorectal Cancer
Assessment of Autologous Blood Marker Localization in Laparoscopic Colorectal Cancer Surgery
Laparoscopic colorectal surgery has been proved to have similar oncological outcomes with open surgery. Due to the lack of tactile perception, surgeons may have misjudgments in laparoscopic colorectal surgery.
- Trial name
- ABILITY (NCT05597384)
- Testing
- Laparoscopic colorectal cancer resection
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Shanghai East Hospital
Colonoscopy
Music Utilization in Sedation and Induction in Colonoscopy
Conscious sedation (CS) if often used in the field of gastroenterology to alleviate pain and discomfort with interventional procedures.
- Trial name
- MUSIC (NCT04468048)
- Testing
- Music: "Nada Himalaya" performed by S. G. Sachchidananda
- Where
- United States
- Sponsor
- The Brooklyn Hospital Center
Colorectal Cancer, Colon Polyp
Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy
One tricky aspect of the recommendations for colonoscopy prep is diet. This has a significant impact on the experience of the patient or participant in the screening program and, on the other hand, low adherence has been found in…
- Conditions
- Colorectal Cancer, Colon Polyp, Colon Adenoma
- Trial name
- CriLi (NCT04664543)
- Testing
- Free diet, Three days low residue diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Parc Taulí Hospital Universitari
Polyps, Colorectal Neoplasm
Colorectal Polyps Screening With Low-dose CT Colonoscopy
This preliminary clinical trial aims to evaluate the performance of the low-dose CT colonoscopy (CTC) with computer aided detection (CAD) on polyps detection compared with optical colonoscopy (OC), and explore the possible…
- Trial name
- NCT03064828
- Testing
- CT colonoscopy(normal dose), CT colonoscopy (low dose)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
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