Clinical trials: Colonoscopy Procedure
Delayed Emergence From Anesthesia
Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy
Ketamine and propofol have been used most frequently agents and remifentanil is used with increasing frequency in recent years. Investigators will compare ketamine-propofol and ketamine-remifentanyl effects on drug consumption…
- Trial name
- NCT02602743
- Testing
- Remifentanyl, Propofol, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Sedation, Endoscopy
Opioid-Free Versus Opioid-Based Sedation for Endoscopic Procedures
This study will compare two different sedation approaches used during gastroscopy, colonoscopy, and endoscopic retrograde cholangiopancreatography (ERCP).
- Conditions
- Sedation, Endoscopy, Colonoscopy, Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Trial name
- NCT07649746
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Colorectal Neoplasms
Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy
Polyethylene glycol is the gold standard of bowel preparation for colonoscopy. The most important disadvantage is high volume of this preparation.
- Trial name
- NCT03242369
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Military University Hospital, Prague
Cognitive Dysfunction
The Effect of Physostigmine on Cognitive Functioning in the Immediate Period After Sedation for Colonoscopy
The purpose of this study is to determine whether the administration of physostigmine in combination with sedation for colonoscopy can minimize the cognitive decline at the time of hospital discharge
- Trial name
- NCT01121497
- Testing
- Physostigmine
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Rabin Medical Center
Colonoscopy
A Safety and Efficacy Comparison of BLI4700 Bowel Preparation Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The objective of this study is to compare the safety and efficacy of BLI4700 bowel preparation to an FDA-approved bowel preparation as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT03261960
- Testing
- BLI4700, Magnesium bowel preparation
- Where
- 20 sites in United States
- Volunteers
- 389 people
- Sponsor
- Braintree Laboratories
Multiple Polyps Right Colon, Large Polyp Right Colon
Megachannel Device for Advanced Colonoscopy
Megachannel is a newly developed colonic access system allowing rapid and multiple passes of the colonoscope to the right colon.
- Conditions
- Multiple Polyps Right Colon, Large Polyp Right Colon, Suspected Polyp Right Colon
- Trial name
- NCT00987896
- Testing
- Colonoscopy with Megachannel™ device loaded
- Where
- Austria
- Volunteers
- 41 people
- Sponsor
- Medical University of Vienna
Colon Polyp
Collecting Recorded Videos of Colonoscopy Screening Tests
The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon…
- Trial name
- NCT03891290
- Testing
- Collecting recorded videos of Colonoscopy screening tests of the general population
- Where
- Israel
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Digestive System Disease
Efficacy, Safety and Tolerability of Eziclen®/Izinova® Versus Klean-prep® on Bowel Cleansing in Adolescents Undergoing Colonoscopy
The purpose of the protocol is to demonstrate that Eziclen®/Izinova®, an osmotic sulphate-based laxative preparation given on the day before colonoscopy has non-inferior efficacy to Klean-Prep® (polyethylene glycol…
- Trial name
- EASYKID (NCT03008460)
- Testing
- Eziclen®/Izinova®, Klean-Prep®
- Where
- 24 sites in Czechia, France and 4 more
- Volunteers
- 250 people
- Sponsor
- Ipsen
Colonic Irrigation
Evaluation of Performance and Safety of Colonic Irrigation With the Colon Hydromat as a Non-oral Bowel Preparation for Colonoscopy
This is a clinical study with a medical device that bears the CE mark (approval for marketing in the EU) and is applied within its intended use.
- Trial name
- NCT04684082
- Testing
- Colonic irrigation with the Colon Hydromat
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Herrmann Apparatebau GmbH
Colorectal Cancer
Screening for Colorectal Cancer With FOBT, Virtual Colonoscopy and Optical Colonoscopy. A Randomized Clinical Trial in the Florence District
RATIONALE: Computed tomographic colonography (CTC) has proven to be accurate in detecting colorectal neoplasms and may be a primary test in colorectal cancer screening.
- Trial name
- SAVE (NCT01651624)
- Testing
- Invitation to screening
- Where
- Italy
- Volunteers
- 16,087 people, healthy volunteers welcome
- Sponsor
- Cancer Prevention and Research Institute, Italy
Procedural Anxiety, Procedural Pain
VR Augmented Human Delivered Integrative Psychotherapy for Colonoscopy Procedural Anxiety and Pain
Colonoscopy is an invaluable tool for the diagnosis and management of colon diseases, especially colorectal cancer (CRC) - the third most common cancer worldwide.
- Trial name
- VRIPanx-COL (NCT06346171)
- Testing
- Virtual Reality Integrative Psychotherapy, Virtual Reality Distraction
- Where
- Romania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Serrated Polyp
Serrated Polyp Detection Rate Between Carbon Dioxide and Air Insufflation
Sessile serrated adenomas are characterized by their flat shape and the presence of a yellow mucus cap overlying the lesion. These morphological features may account for their diagnostic difficulty during colonoscopy.
- Trial name
- NCT03623906
- Testing
- Carbon dioxide insufflation colonoscopy, Air insufflation colonoscopy
- Volunteers
- 1,280 people
- Sponsor
- The Catholic University of Korea
Bowel Preparation, Bowel Preparation for Colonoscopy
A Study to Investigate the Effect of a Meal At 6pm the Day Before the Colonoscopy on the Bowel Cleansing with Plenvu
Bowel cleansing prior to colonoscopy is crucial to be able to perform a high-quality examination. Therefore maximum efforts are made to achieve optimal bowel cleansing including diet restriction and refraining from day-before…
- Conditions
- Bowel Preparation, Bowel Preparation for Colonoscopy, Bowel Cleansing for Colonoscopy, Healthy
- Trial name
- DinNER1006 (NCT06651398)
- Testing
- Lenient diet
- Where
- Belgium
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colonoscopy
Safety and Efficacy of Remimazolam in ASA III and IV Patients Undergoing Colonoscopy
A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in American Society of…
- Trial name
- NCT02532647
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Paion UK Ltd.
Surveillance Colonoscopy
Post-polypectomy Surveillance Interval In High-risk Subjects After Screening Colonoscopy
With many countries initiating population colorectal cancer (CRC) screening, including Hong Kong, more robust guidance for surveillance interval is required to maximize subject's benefit with optimal use of resources.
- Trial name
- NCT04034563
- Testing
- 1) Risk of metachronous advanced neoplasia at 3-year, beyond 3 years surveillance colonoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colonic Polyp, Colonic Adenoma
Nationwide Study of Artificial Intelligence in Adenoma Detection for Colonoscopy
The goal of this trial is to determine whether use of a Computer Assisted Detection (CADe) programme leads to an increase in ADR for either units or individual colonoscopists, independent of setting or expertise
- Conditions
- Colonic Polyp, Colonic Adenoma, Colo-rectal Cancer
- Trial name
- NAIAD (NCT05870332)
- Testing
- GI Genius (GIG)
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Bowel Preparation for Colonoscopy
Individualized Non-pharmacological Intervention for Bowel Preparation
Colonoscopy is essential for the early detection of colorectal cancer. However, inadequate bowel preparation remains a common challenge, associated with reduced adenoma detection rates, prolonged procedure time, and increased…
- Trial name
- NCT07684716
- Testing
- Individualized bowel preparation regimen, Information-framing guidance, Standard bowel preparation guidance
- Where
- China
- Volunteers
- 339 people
- Sponsor
- General Hospital of Shenyang Military Region
Quality of Bowel Preparation
Effect of Simethicone on Colon Preparation During Water Exchange Colonoscopy
Background: Colonoscopy reduces colorectal cancer mortality by enabling early detection and removal of adenomas. Its effectiveness, however, depends heavily on bowel preparation quality and mucosal visibility.
- Trial name
- NCT07674160
- Testing
- Simethicone with PEG, PEG
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Water Exchange Colonoscopy
Minimal Water Exchange Versus Left Water Exchange in Unsedated Colonoscopy
Minimal water exchange colonoscopy is theoretically more convenient and faster than water exchange colonoscopy. But few studies compared the differences between the two methods.
- Trial name
- NCT04952142
- Testing
- minimal water exchange
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Bowel Preparation for Colonoscopy
A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy
The purpose of this study to to see how well Miralax (PEG-3350) and Gatorade cleans the colon before a colonoscopy and how easy it is to take compared to Golytely (PEG-ELS) bowel preparation solution.
- Trial name
- NCT01028573
- Testing
- PEG-ELS (Golytely), Miralax mixed with Gatorade, Miralax
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Southern California Institute for Research and Education
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