Clinical trials: Colonoscopy Procedure
Enhancement of the ADR During Colonoscopy
Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility
The investigators hypothesize that spraying peppermint oil containing L-menthol onto the colonic mucosa during colonoscopy will relax smooth muscle allowing better colonic visualization.
- Trial name
- NCT03286764
- Testing
- Peppermint Oil, Distilled water
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Adenoma
The Impact of Active Nurse Participation on Adenoma Detection During Routine Colonoscopy
Hypothesis-- Nurse observation in addition to the colonoscopist while withdrawing the colonoscope from the cecum leads to a greater adenoma detection rate.
- Trial name
- NCT00859625
- Testing
- nurse observation during colonoscope withdrawal
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yale University
Colonoscopy Pain, Abdominal Distension
Effect of Foot Bath After Colonoscopy
This randomized controlled trial evaluated whether a 30-minute foot bath with warm water (40-41°C) after colonoscopy reduces post-procedure pain and abdominal distension and shortens the time to first passage of flatus.
- Trial name
- FOOTBATH-COL (NCT07636109)
- Testing
- Warm foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kocaeli University
Colonic Diseases
Intravenous Saline Pre-hydration in Patients Undergoing Outpatient Colonoscopy
Colonoscopy and sedation are frequently accompanied by hypotension, which reduces the amount of sedation able to be employed. Blood pressure is restored by the infusion of intravenous normal saline.
- Trial name
- NCT00308152
- Testing
- Infusion of 1 litre of normal saline before colonoscopy
- Where
- Australia
- Volunteers
- 1,000 people
- Sponsor
- The Canberra Hospital
Colonic Polyps, Colonic Neoplasms
Development of Quality Indicators and Quality Improvement Plan of Colonoscopy in Experienced Endoscopist
The purpose of this study is to determine clinical factors affecting quality indicators of colonoscopy including adenoma detection rate, and whether quality of colonoscopy could be elevated by improving related factors.
- Trial name
- NCT02385552
- Testing
- Feedback
- Where
- 2 sites in South Korea
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Manual Pressure, Repositioning
Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower…
- Conditions
- Manual Pressure, Repositioning, Colonoscopy, Colon Polyp
- Trial name
- NCT06496958
- Testing
- CO2 insufflation with an abdominal compression device, Water exchange colonoscopy
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Colon Cancer, Colon Rectal Cancer
EndoStyle: Artificial Intelligence Image Transformation Tool for Colonoscopy
The study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images.
- Trial name
- EndoStyle (NCT06553326)
- Testing
- EndoStyle
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Colorectal Cancer
Effect of Individualized Patient Education Including Drinking Advice Using an App
Study evaluating the effect of a personalized smart phone application in addition to standard care on bowel preparation scores, compared to standard care alone.
- Trial name
- NCT03677050
- Testing
- Smart phone patient education application
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Maastricht University Medical Center
Colorectal Cancer Screening
EFFECTIVENESS OF EARLY INFORMATION AND ENDORSMENT BY GP TO INCREASE COLONOSCOPY FOLLOW-UP AND REDUCE DELAYS IN PEOPLE WITH A POSITIVE COLORECTAL CANCER SCREENING TEST. (SUIVICOLO)
To be effective, organized colorectal cancer screening requires good adherence to diagnostic colonoscopy in the event of a positive test.
- Trial name
- SUIVICOLO (NCT07520578)
- Testing
- Usual care follow-up by CRCDC, Information leaflet about colonoscopy follow-up, Endorsement of CRCDC letters from the GP
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Caen
Gut Microbiota, Bowel Preparation
The Change of Gut Microbiota After Bowel Preparation and the Effect of Probiotics
The purpose of this study is to investigate the relationship between the change of intestinal bacterial flora and the recovery, and the incidence of symptoms such as abdominal discomfort after colonoscopy.
- Conditions
- Gut Microbiota, Bowel Preparation, Colonoscopy
- Trial name
- NCT03760133
- Testing
- Duolac
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kosin University Gospel Hospital
Colonoscopy, Colorectal Cancer Screening
Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East
The purpose of this study is to gain early experience in the Triton 1.5 System in performing diagnostic, screening, surveillance, and basic therapeutic tasks (e.g., polypectomy for lesions ≤ 2 cm).
- Trial name
- CARE-UAE (NCT07835542)
- Testing
- Diagnostic Test: Diagnostic Colonoscopy
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Pronase, Mucosal Clarity
Pronase in Improving Endoscopic Mucosal Clarity During Colonoscopy for Patients with Colitis
Pronase is a proteolytic enzyme known for its ability to clear mucus by breaking down its main component, mucin, through enzymatic hydrolysis.
- Trial name
- NCT06874673
- Testing
- Pronase
- Where
- China
- Volunteers
- 438 people
- Sponsor
- Changhai Hospital
Colo-rectal Cancer, Polyp of Colon
Computer Aided Detection of Polyps During Colonoscopy Procedures
The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
- Trial name
- NCT04195646
- Testing
- EndoVigilant CAD Software
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EndoVigilant Inc
Colonoscopy (Procedure), 18 Years and Over
Online Nursing Counseling and Colonoscopy Outcomes
This randomized controlled experimental study was conducted in the endoscopy unit of a private hospital between March and June 2023 to evaluate the effect of nurse-delivered counseling on pain, anxiety, and comfort levels in…
- Conditions
- Colonoscopy (Procedure), 18 Years and Over, Literacy, No Communication Difficulties
- Trial name
- NCT07664800
- Testing
- Online Nursing Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanko University
Water Assisted Colonoscopy
Impact of Water Assisted Colonoscopy vs Air Insufflation on Resident Training
This study will be a randomized trial comparing the use of only water or water and air insufflation during colonoscopy insertion by trainees.
- Trial name
- NCT04987645
- Testing
- Water-only infusion technique, Water infusion and air insufflation
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Colonic Diseases, Nurse-Patient Relations
Telephone Educational Intervention by the Gastrointestinal Endoscopy Nurse. Global Impact on the Quality of Colonoscopy
This study assesses what impact has on colonoscopy quality the implementation of a telephone educational intervention carried out individually on the patient in the days before the test.
- Conditions
- Colonic Diseases, Nurse-Patient Relations, Educational Problems
- Trial name
- NCT03458377
- Testing
- Educational telephone call
- Where
- Spain
- Volunteers
- 1,534 people
- Sponsor
- Parc de Salut Mar
Colorectal Cancer
Long-term Follow-up Study Designed to Evaluate the Relative Risk of Two Colonoscopy Schedules for Patients With Small Polyps
Colorectal cancer is a leading cause of cancer death in the United States. Mortality remains high because most colorectal cancers are detected after there has been regional or distant spread, precluding curative surgical…
- Trial name
- NCT00032344
- Testing
- Colonoscopy
- Where
- 13 sites in United States
- Volunteers
- 3,200 people
- Sponsor
- US Department of Veterans Affairs
Colorectal Cancer Screening
Promoting Informed Decisions About Cancer Screening in Older Adults
This project aims to examine the impact of different interventions designed to help individualize colorectal cancer (CRC) screening decisions in adults aged 76-85. Clinicians will be assigned by chance to one of two arms.
- Trial name
- PRIMED (NCT03959696)
- Testing
- Notification, Training
- Where
- 5 sites in United States
- Volunteers
- 536 people
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer
Participation to Colorectal Cancer Screening With Fecal Occult Blood Test and Colonoscopy
Adherence rate to screening colonoscopy (TC) in the average-risk general population is still unclear. Aim of this study was to compare the uptake of TC screening with that of fecal occult blood (FOBT) in the general population of…
- Trial name
- NCT00812942
- Testing
- colonoscopy, faecal test
- Where
- Italy
- Volunteers
- 9,889 people
- Sponsor
- Istituto Superiore di Sanità
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