Clinical trials: Colonoscopy Procedure
Post-polypectomy Bleeding, Polypectomy
Risk of Post-polypectomy Bleeding With Prophylactic Hemoclipping
A randomized trial aimed at determining whether or not hemoclips are effective in preventing post-polypectomy bleeds on polyps that are 10mm in size or greater.
- Conditions
- Post-polypectomy Bleeding, Polypectomy, Elective Colonoscopy
- Trial name
- NCT01647581
- Testing
- Hemoclip Placement, NO hemoclip placement
- Where
- 3 sites in United States
- Volunteers
- 11,182 people
- Sponsor
- VA Office of Research and Development
Polyp, Adenoma
EndoCuff-assisted Versus Standard Colonoscopy for Adenoma Detection
The EndoCuff is novel flexible cuff that can be attached to the distal tip of the colonoscope and helps to flatten large mucosal folds during withdrawal.
- Conditions
- Polyp, Adenoma, Cancer
- Trial name
- NCT02034929
- Testing
- EndoCuff-assisted colonoscopy, Standard colonoscopy
- Where
- 4 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Helios Albert-Schweitzer-Klinik Northeim
Colonoscopy Preparation
Comparison of Bowel Cleansing Regimens for Colonoscopy
Colonoscopy is a frequently used method in colon cancer screening today. Routine bowel cleansing is performed for colonoscopy. When the guidelines are examined, there are various recommendations regarding colonoscopy preparation…
- Trial name
- NCT06021639
- Testing
- The last 24 hours will consume low fiber food.
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Mersin University
Colonic Diseases
Computer Aided Detection, Tandem Colonoscopy Study
The purpose of this project is to examine the role of machine learning and computer aided diagnostics in automatic polyp detection and to determine in real-time how a computer-aided detection (CADe) algorithm will perform when…
- Trial name
- NCT04074577
- Testing
- Standard technique First, combination technique First
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Conscious Sedation
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy
Very often patients receive medication before a diagnostic procedure, like a colonoscopy, to help them relax and stay calm during the procedure. This is called procedural or minimal-to-moderate sedation.
- Trial name
- NCT00261599
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI
- Where
- 20 sites in United States
- Volunteers
- 300 people
- Sponsor
- Eisai Inc.
Ulcerative Colitis, Dysplasia
Artificial Intelligence and Dysplasia Detection in Ulcerative Colitis (CUDISIA Study)
Prospective clinical study that analyzes the efficacy of colonoscopy assisted by an artificial intelligence system (DiscoveryTM) compared to virtual chromoendoscopy with iSCAN in the detection of colon dysplasia in patients with…
- Trial name
- CUDISIA (NCT05171634)
- Testing
- DiscoveryTM, iSCAN
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Colonoscopy, Unsedated
Factors Associated With Pain During Unsedated Colonoscopy
Colonoscopy is the gold standard in the diagnosis and treatment colorectal disease, but due to the uncomfortable or even painful procedure, a part of people unwilling to undergoing the examination and giving analgesic agents were…
- Conditions
- Colonoscopy, Unsedated, Pain
- Trial name
- NCT03420612
- Where
- China
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Pain
Routine or On-demand Fentanyl in Colonoscopy
Colonoscopy may be an unpleasant procedure. Sedation and/or analgesics is therefore routinely administered in most countries. In Norway, however, routine sedation is rare, and medication is normally given on demand, that is, if…
- Trial name
- FEKOL (NCT01786434)
- Testing
- Routine medication arm, Fentanyl on-demand arm
- Where
- Norway
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Colonic Diseases
Intravenous Saline Pre-hydration in Patients Undergoing Outpatient Colonoscopy
Colonoscopy and sedation are frequently accompanied by hypotension, which reduces the amount of sedation able to be employed. Blood pressure is restored by the infusion of intravenous normal saline.
- Trial name
- NCT00308152
- Testing
- Infusion of 1 litre of normal saline before colonoscopy
- Where
- Australia
- Volunteers
- 1,000 people
- Sponsor
- The Canberra Hospital
Colonoscopy, Oxygenation
Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy
Nasal continuous positive airway pressure (nCPAP) has been shown to effectively relieve upper airway obstruction in patients with OSA as it creates a pneumatic stent in the hypopharynx that reduces obstruction and allows for…
- Conditions
- Colonoscopy, Oxygenation, Ventilation
- Trial name
- NCT03139448
- Testing
- Oxygen via nasal cannula, Oxygen via SuperNO2VA nasal mask
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Vanderbilt University Medical Center
Colon Cancer, Colon Rectal Cancer
EndoStyle: Artificial Intelligence Image Transformation Tool for Colonoscopy
The study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images.
- Trial name
- EndoStyle (NCT06553326)
- Testing
- EndoStyle
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Colon Adenomas, Colon Polyps
Impact of Computer-aided Detection System on the Right Colon Adenoma Miss Rate
This is a prospective, multicenter randomized controlled trial designed to determine whether the use of computer-aided detection system could reduce the miss rates of adenomas, SSLs, and polyps in the proximal colon during tandem…
- Conditions
- Colon Adenomas, Colon Polyps, Sessile Serrated Lesion
- Trial name
- NCT07308743
- Testing
- Computer-aided detection-assisted colonoscopy, Conventional white-light colonoscopy
- Where
- China
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Esophagogastroduodenoscopy, Colonoscopy
Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation
The purpose of this study is to determine residual gastric volume and residual gastric pH in patients undergoing combined EGD and colonoscopy comparing the standard single dose prep with the split dose bowel preparation and same…
- Trial name
- NCT02264249
- Testing
- Esophagogastroduodenoscopy and colonoscopy split dose prep, Esophagogastroduodenoscopy and colonoscopy Evening before colonoscopy prep, Esophagogastroduodenoscopy and colonoscopy Same day prep colonoscopy preparation
- Where
- United States
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Abdominal Pain, Distention
Foot and Abdominal Massage Applied to After Colonoscopy
The aim of this study was to determine the effect of foot and abdominal massage applied to after colonoscopy on abdominal distention, pain and patient satisfaction.This was a randomized controlled experimental study conducted at…
- Conditions
- Abdominal Pain, Distention, Satisfaction, Patient
- Trial name
- NCT06333535
- Testing
- foot massage, abdominal massage, foot and abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- TC Erciyes University
Quality Evaluation System for Colonoscopy
Prospective Multicenter Study of Artificial Intelligence-assisted Quality Evaluation System for Colonoscopy
The quality control index based on artificial intelligence is put forward to monitor the quality of enteroscopy. And we will verify the correlation between the detection rate of adenomas and the percentage of endoscopic overspeed…
- Trial name
- NCT04610177
- Where
- China
- Volunteers
- 5,813 people
- Sponsor
- Renmin Hospital of Wuhan University
Colonoscopy, Colon Disease
Three Distraction Methods for Pain Reduction During Colonoscopy
Colonoscopy is a common procedure to evaluate the gastrointestinal tract. The colonoscopy procedure can sometimes be uncomfortable and painful for the patient.
- Trial name
- NCT05378165
- Testing
- Music group, Stress ball group, Video group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Colorectal Cancer Control and Prevention
Appropriateness of Colonoscopy Indication: an Evaluation of the Clinical and Economic Impact.
The aim of the study is to evaluate the appropriateness of colonoscopy prescription and the impact of colonoscopies in diagnostic performance in order to develop and validate a predictive model for selecting patients most likely…
- Trial name
- PROMOTE (NCT06775951)
- Where
- 2 sites in Italy
- Volunteers
- 1,410 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colonic Polyps
Cathartic-Free DECT Colonography for Detection of Colonic Polyps
Asses the clinical performance of dual-energy CTC for the detection of larger polyps 1 cm or larger without cathartic preparation.
- Trial name
- NCT00587028
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Colonoscopy
F38-27: An Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To compare the safety and efficacy of 2 different bowel cleansing preparations prior to colonoscopy in adult subjects.
- Trial name
- NCT00857272
- Testing
- PEG electrolyte lavage solution + bisacodyl - reformulation, PEG electrolyte lavage solution + bisacodyl
- Where
- 6 sites in United States
- Volunteers
- 308 people
- Sponsor
- Braintree Laboratories
Cancer, Colo-rectal Cancer
Gut Microbiota and Color-rectal Cancer.
This clinical trial is focused in the development of a screening test for the people at risk of colo-rectal cancer (aged more than 50 years old), valid and safe, improving the screening prognosis increasing the sensitivity and…
- Conditions
- Cancer, Colo-rectal Cancer, Diagnoses Disease, Microbiota-related Disease
- Trial name
- CCR-microbiota (NCT04662853)
- Testing
- Gut microbiota determination from feces samples.
- Where
- Spain
- Volunteers
- 153 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
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