Clinical trials: Colonoscopy Procedure
Colonic Polyps, Artifical Intelligence
The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic Lesion
The goal of this prospective study is to to evaluate the prevalence of metachronous advanced colonic lesions in subsequent surveillance colonoscopies in patients who had previously undergone AI-assisted colonoscopy to…
- Conditions
- Colonic Polyps, Artifical Intelligence, Advanced Metachonous Colonic Lesion
- Trial name
- NCT07467928
- Testing
- Suveillance colonoscopy
- Where
- Hong Kong
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colonoscopy Preparation
The Effect of Adding Lubiprostone to Standard Large-Volume PEG-ELS on The Quality of Inpatient Colonoscopy Preparation
This is a multicenter interrupted-time series study. The study will include patients between the age of 18-85 year old, both males and females, who are scheduled for inpatient colonoscopy procedure.
- Trial name
- NCT04361656
- Testing
- PEG-ELS current standard of care, PEG-ELS current standard of care plus Lubiprostone 24 microgram Oral Cap (x2)
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Colonoscopy
Effect of Intraluminal Administration of Menthol Solution During Colonoscopy on Colonic Spasm and Adenoma Detection Rate
In recent years, with increasing research into antispasmodic agents, topical antispasmodics have attracted considerable attention due to their direct action on the gastrointestinal mucosa and relatively low incidence of adverse…
- Trial name
- NCT07501962
- Testing
- Endoscopic irrigation was performed using a 0.1% menthol solution combined with simethicone., Endoscopic irrigation was performed using an aqueous suspension prepared with simethicone and normal saline.
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Bowel Preparation Solution
PEG-Asc Vs. SPMC for Bowel Preparation in Capsule-based Procedures
This clinical research study is designed to find out which of two different types of bowel preparation works best for people undergoing capsule-based endoscopy procedures.
- Trial name
- NCT07206329
- Testing
- Polyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC)
- Where
- Portugal
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Colorectal Cancer
Comparative Effectiveness of FIT, Colonoscopy, & Usual Care Screening Strategies
Colorectal cancer (CRC) is the 2nd leading cause of cancer death in the US, though CRC death can be reduced by screening. However, there is uncertainty as to which screening strategy is most clinically and cost-effective from a…
- Trial name
- NCT01710215
- Testing
- FIT Screening Strategy, Colon Screening Strategy
- Where
- United States
- Volunteers
- 5,999 people
- Sponsor
- University of Texas Southwestern Medical Center
Chromoendoscopy
Chromocolonoscopy With Food-grade Dyes
Previous with methylene blue suggested that oral administration may be superior to conventional spray catheters. The main advantages claimed were better staining due to longer exposure to the dye, more uniform staining due to…
- Trial name
- NCT02631798
- Testing
- Food grade dye mucosal staining
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Colorectal Cancer, Adenoma Colon
Evaluation of Colonoscopy With a Specific Device for the Detection of Adenomas
Evaluation of colonoscopy with a specific device for the detection of adenomas: Multicenter, prospective and randomized study
- Trial name
- ENDOCOLES (NCT03436004)
- Testing
- Colonoscopy, Colonoscopy with specific device (Endocuff Vision)
- Where
- 8 sites in Spain
- Volunteers
- 1,453 people
- Sponsor
- Dr. Alberto Herreros de Tejada Echanojáuregui
Adenoma Detection Rate
Artificial Intelligence-assisted Colonoscopy With or Without Endocuff Vision
Adenoma detection rate (ADR) is considered the single most important quality measure in colonoscopy and a higher ADR can reduce the risk of interval colorectal cancer (CRC).
- Trial name
- NCT05863208
- Testing
- Artificial intelligence, Endocuff vision, High-definition endoscope
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- E-DA Hospital
Colonic Adenomas
The Impact of Split Dose of Low-volume Polyethylene Glycol on Adenoma Detection Rate
An adequate level of bowel preparation is crucial for the efficacy and safety of colonoscopy. Strong evidences suggest that bowel-preparation quality shows an inverse correlation with length of the interval between the end of…
- Trial name
- NCT02178033
- Testing
- Split dose low-volume PEG solution
- Where
- 2 sites in Italy
- Volunteers
- 514 people
- Sponsor
- Valduce Hospital
Colorectal Canceer
Usefulness of Endocuff in the Adenoma Detection Rate. Comparative Study
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. The cumulative risk of developing CRC is about 6% lifelong.
- Trial name
- NCT02387593
- Testing
- ENDOCUFF
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Narrow Band Imaging
Comparison of ADR Using NBI Versus HD White Light Colonoscopy in Screening and Surveillance Colonoscopies
The aim of this study is to compare ADR using HD-NBI or HD-WLE during screening and surveillance colonoscopies.
- Trial name
- NCT03081975
- Testing
- HD white light or NBI
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Colon Neoplasm
Comparing Water Exchange, Water Immersion and Air Insufflation Methods During Colonoscopy With the Option of on Demand Sedation
This prospective, randomized controlled trial compares traditional air insufflation with water immersion and water exchange in patients undergoing colonoscopy using on demand sedation.
- Trial name
- NCT01699399
- Testing
- water immersion, water exchange, air insufflation
- Where
- Taiwan
- Volunteers
- 225 people
- Sponsor
- Dalin Tzu Chi General Hospital
Colonic Adenomas
Soft Coagulation for the Prevention of Adenoma Recurrence
Recurrence after endoscopic mucosal resection of laterally spreading lesions (LSL) >= 20mm in size occurs in approximately 20% of cases at surveillance colonoscopy.
- Trial name
- SCAR (NCT01789749)
- Testing
- Snare Tip Soft Coagulation, No Snare Tip Soft Coagulation
- Where
- 4 sites in Australia
- Volunteers
- 455 people
- Sponsor
- Professor Michael Bourke
Colorectal Adenoma, Colorectal Polyp
Intubation Techniques on Colonoscopy Quality (SINOCOLO2013)
The primary aim of this study is to explore the usefulness of abdominal compression on intubation. Other aims include 1. to investigate the effectiveness and the efficacy of different manners of abdominal compression and to…
- Trial name
- SINOCOLO2013 (NCT01919463)
- Testing
- Abdominal Compression, Guidance of Magnetic Endoscopic Imaging (MEI) System
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Functional Constipation, Irritable Bowel Syndrome
Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
The purpose of this project is to study the the efficacy and safety of probiotics implantation through infusion during colonoscopy in the treatment of functional constipation and irritable bowel syndrome.
- Conditions
- Functional Constipation, Irritable Bowel Syndrome, Probiotics, Colonoscopy
- Trial name
- CPIFGD (NCT05366335)
- Testing
- Live Combined Bifidobacterium and Lactobacillus, Normal saline, Basic treatment
- Where
- China
- Volunteers
- 160 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Preparation for Colonoscopy
Safety and Efficacy of High Dose Bowel Preparation Solutions for Patients With Difficult To Clean Colons For Colonoscopy
The purpose of this study is to document the safety and effectiveness of high doses of liquids to clean the colon for colonoscopy in patients who had a previous colonoscopy with a poorly cleaned colon.
- Trial name
- NCT02661750
- Testing
- Bowel Preparation
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Gastroenterology Services, Ltd.
Sedation Problems
Role of Respiratory Rate Derived From Capnography in Sedated Patients
Although appropriate sedation is recommended during colonoscopy, patients are at risk for adverse events e.g hypoventilation and hypoxemia due to inadvertent oversedation.
- Trial name
- NCT05793658
- Testing
- Standard capnography, Modified capnography
- Where
- Saudi Arabia
- Volunteers
- 74 people
- Sponsor
- Al Jedaani Hospital
Acute Kidney Failure
Change of Neutrophil Gelatinase-Associated Lipocalin(NGAL) Following Sodium Phosphate Bowel Preparation(Pilot Study)
Oral phosphate purgative is the preferred bowel regimen on the basis of better tolerability, cost effectiveness, and efficacy. There are also numerous reports of patients with even previously normal renal function developing…
- Trial name
- NCT00760591
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Soon Chun Hyang University
Musculoskeletal Pain
Kinesio-taping Versus Pelvic Floor Exercise for Post Colonoscopy Coccydynia
Forty-two patients, with coccydynia following colonoscopy were selected from Kasr El-Aini teaching Hospital, with age ranged from 25-45 years. Patients were randomly assigned to the control or experimental groups.
- Trial name
- NCT04261647
- Testing
- kinesio-taping techniques., Pelvic floor exercise, traditional physical therapy program , stretching of piriformis. iliopsoas, clam shell exercise,seat cushioning and seat kitz.
- Volunteers
- 42 people
- Sponsor
- Hadaya Mosaad
Colonoscopy
A Pilot Evaluation of BLI4700 Bowel Preparation in Adult Subjects
The objective of this study is to evaluate the safety and efficacy of BLI4700 as a bowel preparation prior to colonoscopy in adult patients.
- Trial name
- NCT03023085
- Testing
- BLI4700
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Braintree Laboratories
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