Clinical trials: Colonoscopy Procedure
Conscious Sedation
Conscious Sedation for Outpatient Colonoscopy
Although colonoscopy is a mildly painful procedure, the pain and the procedure itself are distressful for most patients. This raises the attention for using different sedation regimens aiming at maintaining optimal sedation level…
- Trial name
- NCT03925779
- Testing
- Dexmedetomidine, Propofol, Remifentanil
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Polyps
Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
This is a test in which a thin, black, flexible tube with a lighting system on the end is passed through the anus, into the rectum, in order to examine the large bowel or intestine, also called the colon.
- Trial name
- NCT00577083
- Testing
- Cap-fitted colonoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonic Adenoma, Water Exchange Colonoscopy
Adenoma Miss Rate With Water Exchange vs Carbon Dioxide Colonoscopy
This was an observational study comparing consecutive group of WE and CO2 insufflation in terms of right and proximal colon AMR by tandem colonoscopy.
- Trial name
- NCT03832322
- Testing
- Water exchange colonoscopy, CO2 insufflation colonoscopy
- Where
- Taiwan
- Volunteers
- 176 people
- Sponsor
- Evergreen General Hospital, Taiwan
Melena Due to Gastrointestinal Hemorrhage
The Role of Push Enteroscopy in Patients With Passing Melena With Nondiagnostic EGD.
Melena is often caused by upper gastrointestinal (GI) bleeding; therefore, esophagogastroduodenoscopy (EGD) is the first preferred diagnostic tool. However, EGD fails to identify the bleeding source in about 25% of cases.
- Trial name
- NCT06574542
- Testing
- Push enteroscopy (PE), Colonoscopy
- Where
- Thailand
- Volunteers
- 77 people
- Sponsor
- Mahidol University
Diabetes Mellitus, Colonic Diseases
Diet for Colonoscopy Preparation in Diabetic Patients
This trial will compare the efficacy of to 2 different sets of dietary recommendations to be followed before colon cleansing for colonoscopy in diabetic patients.
- Trial name
- DIMEPREP (NCT02300779)
- Testing
- Low-residue diet, Usual care
- Where
- 2 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Parc de Salut Mar
Colorectal Neoplasms, Colorectal Cancer
Use of iFOBT in Patients Presenting With Alarm Symptoms of Colorectal Cancer
Background: Colorectal cancer (CRC) is one of the most common types of cancer in Denmark, and mortality among patients is high. Patients presenting with alarm symptoms of CRC are referred to colonoscopy in the cancer patient…
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colorectal Carcinoma, Colorectal Adenoma
- Trial name
- NCT03367611
- Testing
- Immunochemical faecal occult blood test (iFOBT)
- Where
- Denmark
- Volunteers
- 1,258 people
- Sponsor
- University of Aarhus
Artificial Intelligence, Colonic Adenoma
Artificial Intelligence-Assisted Colonoscopy in Colorectal Cancer Screening in a General Hospital
Cancer can develop in the colon, or large bowel. Examination of the colon with a tube fitted with a camera is called a colonoscopy. Colonoscopy allows detection of small growths in the colon, called "polyps".
- Conditions
- Artificial Intelligence, Colonic Adenoma, Colonic Neoplasms, Colonic Polyp
- Trial name
- Delta-AI (NCT06792292)
- Testing
- conventional colonoscopy procedure, artificial intelligence-assisted colonoscopy procedure
- Where
- Belgium
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Chirec
Any Symptoms Requiring Colonoscopy
The Effect of ScopeGuide on the Mental Workload of Endoscopist
ScopeGuide (Magnetic endoscopic imaging) is a device used during some colonoscopies which provides real-time 3D image of the shape and configuration of the colonoscope as it travels through the colon.
- Trial name
- NCT02092493
- Testing
- ScopeGuide
- Where
- United Kingdom
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Failed Conscious Sedation During Procedure
Magnetic Endoscope Imaging in Colonoscopy: Influence on Propofol Dosage
Magnetic Endoscope Imaging (MEI) is an optional tool which can be switched on at the beginning of colonoscopy. MEI works by creating an electromagnetic field of very low intensity.
- Trial name
- MEXICO (NCT02121704)
- Testing
- Magnetic Endoscope Imaging (Scope Guide)
- Where
- Germany
- Volunteers
- 334 people
- Sponsor
- Technical University of Munich
Colorectal Polyps
Role of Computer-Aided Detection Colonoscopy in Polyp Detection Rate
High-definition (HD) colonoscopy is the gold standard for early diagnosis and treatment of lower gastrointestinal neoplasms, with the adenoma detection rate (ADR) serving as a key quality indicator due to its inverse correlation…
- Trial name
- CADEC (NCT07171333)
- Testing
- Colonoscopy with CADe system
- Where
- Italy
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Gian Eugenio Tontini
Bowel Preparation for Colonoscopy
Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy
The clinical purpose of this study was to investigate whether the adjuvant application of linaclotide in bowel preparation for colonoscopy could improve the quality of bowel preparation or reduce the dosage of laxatives.
- Trial name
- NCT05291325
- Testing
- 3L PEG + Linaclotide, 3L PEG, 2L PEG + Linaclotide
- Where
- China
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Screening Colonoscopy, Colonoscopic Control After Polypectomy
Study on the Use of Artificial Intelligence (Fujifilm) for Polyp Detection in Colonoscopy
Colonoscopy is currently the best method of detection of intestinal tumors and polyps, particularly because polyps can also be biopsied and removed.
- Conditions
- Screening Colonoscopy, Colonoscopic Control After Polypectomy, Suspected Colon Polyps
- Trial name
- Fuji AI (NCT04894708)
- Testing
- colonoscopy
- Where
- 10 sites in Germany
- Volunteers
- 1,572 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colonic Neoplasms
Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel Preparation in Low-risk Patients
Adequate quality of bowel preparation(BP) is essential for colonoscopy. In recently, Kang suggested that for low-risk patients, single dose of 2L PEG is an effective regimen for bowel preparation.However, due to the poor…
- Trial name
- NCT05648318
- Testing
- Lactulose oral solution, PEG
- Where
- China
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Zhang Xiaofeng,MD
Colorectal Adenoma, Colorectal Adenomatous Polyp
Analysis of New Endoscopic Features and Variable Stiffness in Colonoscopy: Prospective Randomised Trial
The aim of the present study is to develop and evaluate a computer-based methods for automated and improved detection and classification of different colorectal lesions, especially polyps.
- Trial name
- ELUFIBLI (NCT03234725)
- Where
- Hungary
- Volunteers
- 1,000 people
- Sponsor
- Bács-Kiskun County Teaching Hospital
Colonoscopy, Ketamine
Comparison of Efficacy of Anesthesia Administered by Endoscopist or Anesthesiologist on Colonoscopy
In sedation applications performed by an endoscopist or anesthetist during colonoscopy, it was investigated whether there were differences in pain levels evaluated by VAS (Visuel analog scale), patient satisfaction, duration of…
- Conditions
- Colonoscopy, Ketamine, Fentanyl
- Trial name
- NCT03607110
- Testing
- Ketamine, fentanyl, patient control analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Selda KAYAALTI
Cognitive Impairment
Cognitive Impairment Following Sedation for Colonoscopy With Propofol, Midazolam and Fentanyl Combinations
Our hypothesis is that adding midazolam and/or fentanyl to propofol sedation for elective outpatient colonoscopy increases cognitive impairment at hospital discharge without improving intraoperative conditions or reducing…
- Trial name
- NCT00446420
- Testing
- Propofol, midazolam, fentanyl
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Melbourne Health
Gut Microbiota, Bowel Preparation
The Change of Gut Microbiota After Bowel Preparation and the Effect of Probiotics
The purpose of this study is to investigate the relationship between the change of intestinal bacterial flora and the recovery, and the incidence of symptoms such as abdominal discomfort after colonoscopy.
- Conditions
- Gut Microbiota, Bowel Preparation, Colonoscopy
- Trial name
- NCT03760133
- Testing
- Duolac
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kosin University Gospel Hospital
Abdominal Pain, Distention
Foot and Abdominal Massage Applied to After Colonoscopy
The aim of this study was to determine the effect of foot and abdominal massage applied to after colonoscopy on abdominal distention, pain and patient satisfaction.This was a randomized controlled experimental study conducted at…
- Conditions
- Abdominal Pain, Distention, Satisfaction, Patient
- Trial name
- NCT06333535
- Testing
- foot massage, abdominal massage, foot and abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- TC Erciyes University
Colorectal Cancer
Comparative Effectiveness of CTC & OC
The goal of this study is to compare the findings of virtual (CT-colonography) with findings of optical colonoscopies to determine if virtual colonoscopy is suitable for colorectal cancer surveillance.
- Trial name
- NCT02143115
- Testing
- Optical colonoscopy, CT-Colonography
- Where
- 5 sites in United States
- Volunteers
- 244 people
- Sponsor
- Fox Chase Cancer Center
Familial Adenomatous Polyposis
Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers
Primary Objective: To determine whether celecoxib downregulates GATA-6 expression to upregulate 15-LOX-1 expression and induce apoptosis in human rectal tumors, researchers will measure GATA-6 and 15-LOX-1 expression, 13-S-HODE…
- Trial name
- NCT00503035
- Testing
- Celecoxib, Colonoscopy Biopsy
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- M.D. Anderson Cancer Center
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