Clinical trials: Colonoscopy Procedure
Colorectal Cancer
PillCam Colon Capsule and CT-colonography in the Evaluation of Patients With Incomplete Conventional Colonoscopy
Colorectal cancer (CRC) is the second most common cause of cancer-related death in the Western world, with 500000 deaths per year worldwide. Colonoscopy is accepted as a primary CRC screening tool in many countries.
- Trial name
- NCT01525940
- Testing
- PillCam Colon Capsule Endoscopy (Given® Diagnostic System)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Multicenter Evaluation of Right Colon Polyp Miss Rates Using Water Exchange Versus CO2 Insufflation
A prospective multicenter randomized controlled trial (RCT) comparing water exchange (WE) colonoscopy and carbon dioxide (CO2) insufflation in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate…
- Trial name
- NCT04124393
- Testing
- Colon Polypectomy
- Where
- Taiwan
- Volunteers
- 386 people
- Sponsor
- Evergreen General Hospital, Taiwan
Healthy
Evaluation of PICOLIGHT Plus COOLPREP, PICOLIGHT Plus CLICOLON for Bowel Preparation
The purpose of this study to bowel cleansing evaluation of mixed two other type bowel preparation drug(PICOLIGHT plus COOLPREP, PICOLIGHT plus CLICOLON).
- Trial name
- NCT01919255
- Testing
- Picolight + Coolprep, Picolight + Clicolon
- Where
- South Korea
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Conscious Sedation
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy
Very often patients receive medication before a diagnostic procedure, like a colonoscopy, to help them relax and stay calm during the procedure. This is called procedural or minimal-to-moderate sedation.
- Trial name
- NCT00261599
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI
- Where
- 20 sites in United States
- Volunteers
- 300 people
- Sponsor
- Eisai Inc.
Colonoscopy, Adenoma Detection Rate
Retroflexion In The Ascending Colon Is A Costless Endoscopic Maneuver Increasing Adenoma Detection Rate
Missing polyps during colonoscopy is considered an important factor for interval cancer appearance especially in the ascending colon (AC).
- Conditions
- Colonoscopy, Adenoma Detection Rate, Adenoma Miss Rate, Retroflexion
- Trial name
- NCT04086706
- Testing
- Retroflexion in the Right Colon
- Where
- Greece
- Volunteers
- 655 people
- Sponsor
- Alexandra Hospital, Athens, Greece
Colonoscopy
Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening
To compare the efficacy, acceptability and safety of the new 2 liter gut cleansing solution (Moviprep) and NaP preparation in routine colon cleansing prior to tumor screening colonoscopies
- Trial name
- NCT00427089
- Testing
- Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate, Sodium Phosphate solution (NaP)
- Where
- 12 sites in Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Norgine
Adenoma
The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy
The aim of this study was to determine whether segmental re-examination of the each segment (right colon, mid-colon, and left colon) could increase the proximal adenoma detection rate (ADR) and to evaluate the time-effectiveness…
- Trial name
- NCT03268200
- Testing
- segmental reexamination
- Where
- South Korea
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Colorectal Cancer
Is Barium Enema an Adequate Diagnostic Test for Patients With Positive FOBT?
The research protocol aim is to compare diagnostic tools for the proper evaluation of patient with fecal occult blood test positive (FOBT +), a routine screening test for colorecatl carcinoma.
- Trial name
- DCBE (NCT00619814)
- Testing
- Double-contrast Barium enema, colonoscopy
- Volunteers
- 50 people
- Sponsor
- VA Caribbean Healthcare System
Colo-rectal Cancer, Colon Polyp
Optimizing Timing of Follow-up Colonoscopy
Overall Objective: To optimize timing of surveillance colonoscopy. Principal research question and specific aims: To assess the impact of access to a hand-held application on the timing of surveillance colonoscopy.
- Conditions
- Colo-rectal Cancer, Colon Polyp, Colonic Polyp, Rectal Polyp
- Trial name
- NCT04889352
- Testing
- Access to colonoscopy web app
- Where
- 2 sites in Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Colonoscopy
Safety and Efficacy of Remimazolam in ASA III and IV Patients Undergoing Colonoscopy
A prospective, double-blind, randomized, placebo and active controlled, multi-center, parallel group study comparing remimazolam to placebo, with an additional open-label arm for midazolam, in American Society of…
- Trial name
- NCT02532647
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Paion UK Ltd.
Colonic Adenoma, Colonic Polyp
PROSpective Assessment of Post EmR Recurrence
To prospectively validate the SERT (Sydney EMR Recurrence Tool) scoring system for adenoma recurrence rates around the endoscopic mucosal resection (EMR) scar after wide field-EMR with thermal treatment applied to the defect…
- Trial name
- PROSPER (NCT02957058)
- Testing
- SCAR technique
- Where
- Australia
- Volunteers
- 700 people
- Sponsor
- Western Sydney Local Health District
Colonoscopy
A Clinical Validation Study of a Computerized Movement Analysis of the Colonoscope
Colonoscopy is the considered gold standard for diagnosing diseases in the colon. A colonoscopy is normally divided into the insertion from anus to cecum, the technical difficult part, and a retraction or diagnostic part.
- Trial name
- NCT03587935
- Testing
- 3D-Colonoscopy Progression Score, 3D-Colonoscopy Retraction Score
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colonic Polyp
Intraluminal Peppermint Oil and Adenoma Detection Rate in Screening Colonoscopy
This is a prospective randomized placebo-controlled trial to evaluate the efficacy of peppermint oil spraying into the colonic lumen through the scope channel during screening colonoscopy.
- Trial name
- NCT05559814
- Testing
- Intraluminal peppermint oil
- Where
- Thailand
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Elective Colonoscopy
Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®
The purpose of this dose finding/comparative efficacy study is to first single out the most appropriate dose of mannitol for bowel preparation (phase II) and, subsequently, demonstrate the non-inferiority of the efficacy of…
- Trial name
- SATISFACTION (NCT04759885)
- Testing
- Phase II: NTC015 low dose, Phase II: NTC015 medium dose, Phase II: NTC015 high dose
- Where
- 35 sites in France, Germany and 2 more
- Volunteers
- 886 people
- Sponsor
- NTC srl
Colon Cancer Prevention, Polyp Colorectal
Delayed Surveillance Colonoscopy Following Piecemeal EMR
This multicenter, prospective, randomized non inferiority trial, conducted at four Israeli hospitals, will evaluate whether a relaxed surveillance strategy after piecemeal endoscopic mucosal resection (pEMR) of large non…
- Trial name
- NCT07328308
- Testing
- Colonoscopy after bowel cleansing
- Where
- Israel
- Volunteers
- 760 people
- Sponsor
- Rambam Health Care Campus
Pain, Anxiety
Effect of Music Over the Tolerance to Colonoscopy.
This study will evaluate the efficacy of music (a very well selected list of songs)on improving the tolerance to the colonoscopy. The patients will be randomly assigned to receive music or not.
- Trial name
- EMOC (NCT01285284)
- Testing
- Music, No music
- Where
- 4 sites in Chile
- Volunteers
- 300 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection.
- Trial name
- NCT03845933
- Testing
- Colon polypectomy
- Where
- Taiwan
- Volunteers
- 262 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer
Trial Comparing Moviprep and Phosphoral as Bowel Prep Before Colonoscopy
Using Moviprep patients use shorter time to do a bowel prep before colonoscopy. No major single center has docuemted the advantage of using moviprep as bowel prep before colonoscopy.This randomised study was conducted to compare…
- Trial name
- NCT01519609
- Testing
- bowel prep before endoscopy
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Randers Regional Hospital
Sedative During Endoscopy
Implementing Virtual Reality (VR) to Reduce Sedation
The study is a prospective pilot patients aged 21 to 65 undergoing screening colonoscopy or diagnostic upper endoscopy. Patients are administered minimal sedation (2 mg of Versed and 25 mg of Fentanyl) and are given Virtual…
- Trial name
- NCT06349564
- Testing
- Pico 4 Enterprise headset with noise cancelling headphones
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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