Clinical trials: Colonoscopy Procedure, active
Colorectal Carcinoma
A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers
This clinical trial evaluates a clinic-wide intervention called Primary Care-Gastrointestinal (GI) Connect for improving follow-up colonoscopy rates in patients at a Federally Qualified Health Center (FQHC) who have an abnormal…
- Trial name
- NCT06568016
- Testing
- Best Practice, Communication Intervention, Coordination
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10…
- Trial name
- FORTE (NCT05080673)
- Testing
- 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
- Where
- 493 sites in United States, Puerto Rico
- Volunteers
- 9,500 people
- Sponsor
- NRG Oncology
Colonoscopy
Novel Irrigation Solution for Colonoscopy Visualization Pilot
The purpose of this study is to assess the provider experience with a novel colonoscopy irrigation solution and determine the feasibility of introducing this solution into the endoscopy unit and assess efficacy on a small scale…
- Trial name
- NCT07769905
- Testing
- Olympus colonoscope, Irrigation solution
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- NYU Langone Health
Colorectal Polyps
Accuracy and Sustainability of SCALE-EYE Evaluation for Measuring Reliable Polyp Size
A multicenter, randomized, parallel group, endoscopist blinded study to assess the diagnostic performance and sustainability of SCALE-EYE in a screening and surveillance colonoscopy population.
- Trial name
- ASSEMBLE (NCT07005453)
- Testing
- SCALE-EYE (1), SCALE-EYE (2)
- Where
- 3 sites in Netherlands
- Volunteers
- 241 people
- Sponsor
- Erasmus Medical Center
Cirrhosis, Bowel Preparation
Evaluation of a Modified Bowel Preparation Regimen in Cirrhotic Patients Undergoing Colonoscopy
Inadequate bowel preparation compromises colonoscopy quality and diagnostic accuracy, and cirrhosis is a recognized independent predictor of poor bowel cleansing.
- Trial name
- CIRRHOPREP (NCT07668778)
- Testing
- 2-L PEG plus bisacodyl plus 3-day low fibre diet, 2-L PEG plus 1-day low fibre diet
- Where
- 4 sites in Portugal
- Volunteers
- 252 people
- Sponsor
- Hospital do Divino Espírito Santo de Ponta Delgada
Colonoscopy, Bowel Preparation
A Study to Evaluate the Safety and Effectiveness of MSP01-T for Bowel Cleansing Before a Colonoscopy
This study is being conducted to evaluate the safety and effectiveness of MSP01-T, a new bowel cleansing agent, in adults who are scheduled to undergo a colonoscopy.
- Trial name
- MSP01 (NCT07181148)
- Testing
- MSP01-R, MSP01-T
- Where
- South Korea
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Mather's Pharm. Co., Ltd.
Colonoscopy, Colorectal Cancer Screening
Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions
This study is a prospective, single-arm, non-randomized, single site first-in-human study and will be conducted in two phases, where Phase A will serve to evaluate the safety of the Triton 4.0 System to perform screening…
- Conditions
- Colonoscopy, Colorectal Cancer Screening, Colorectal Neoplasms, Gastrointestinal Endoscopy
- Trial name
- CARE I (NCT06935734)
- Testing
- Diagnostic Colonoscopy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Adenoma Detection Rate, Colonoscopy
Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test Group
Background: Adenoma detection rate is one of the most quality indicator: an accumulating body of evidence has shown that detection and resection of pre-cancerous adenoma by colonoscopy could effectively prevent colorectal cancer…
- Conditions
- Adenoma Detection Rate, Colonoscopy, Three Dimensional, Fecal Immunochemical Test
- Trial name
- NCT06678477
- Testing
- 3D device
- Where
- 3 sites in Taiwan
- Volunteers
- 298 people
- Sponsor
- National Taiwan University Hospital
IBD (Inflammatory Bowel Disease), Colonoscopy
Analysis of Factors Influencing the Quality of Bowel Preparation Before Colonoscopy in IBD Patients
The primary objectives of this project are twofold. On the one hand, it aims to investigate the current status of bowel preparation protocols and their quality in IBD patients undergoing colonoscopy, particularly focusing on the…
- Conditions
- IBD (Inflammatory Bowel Disease), Colonoscopy, Colonoscopy: Bowel Preparation
- Trial name
- NCT07335705
- Testing
- Standard Pre-colonoscopy Bowel Preparation Protocol
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer Control and Prevention
Appropriateness of Colonoscopy Indication: an Evaluation of the Clinical and Economic Impact.
The aim of the study is to evaluate the appropriateness of colonoscopy prescription and the impact of colonoscopies in diagnostic performance in order to develop and validate a predictive model for selecting patients most likely…
- Trial name
- PROMOTE (NCT06775951)
- Where
- 2 sites in Italy
- Volunteers
- 1,410 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colorectal Neoplasia, Screening Colonoscopy
Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial
Colorectal cancer (CRC), the third most diagnosed cancer and second most common cause of cancer death. CRCs develop from precursors like adenomas (about 70% of CRCs) or serrated lesions (SSLs) (about 25-30% of CRCs).
- Conditions
- Colorectal Neoplasia, Screening Colonoscopy, Colorectal Cancer, Colorectal Cancer Screening
- Trial name
- NCT06333392
- Testing
- Total underwater colonoscopy, Conventional colonoscopy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 1,070 people
- Sponsor
- Vestre Viken Hospital Trust
Ciprofol
Ciprofol's Influence on LVOT VTI in Elderly Painless Colonoscopy Patients
1. Objective: Primary: Compare the effect of Ciprofol vs Propofol on LVOT VTI at 2 minutes post-injection (T1) in elderly patients (≥65 years).
- Trial name
- NCT07081477
- Testing
- Intravenous Anesthetic Induction with Ciprofol for Painless Colonoscopy in Elderly Patients, Propofol Intravenous Anesthesia Induction for Painless Colonoscopy in Elderly Patients
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Lynch Syndrome
Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome
Lynch syndrome is the most common hereditary cancer syndrome and is caused by pathogenic variants in DNA mismatch repair genes, resulting in a markedly increased lifetime risk of colorectal cancer.
- Trial name
- Lynch syndrome (NCT07445828)
- Testing
- colon capsule endoscopy
- Where
- Sweden
- Volunteers
- 78 people
- Sponsor
- Region Skane
Acute Kidney Injuries
the Percent of AKI Occurred in Patient With Comorbidities Undergoing Colonoscopy
observation the percent AKI in patient with comorbidities undergoing colonoscopy
- Trial name
- NCT06743815
- Volunteers
- 113 people
- Sponsor
- Assiut University
Manual Pressure, Repositioning
Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower…
- Conditions
- Manual Pressure, Repositioning, Colonoscopy, Colon Polyp
- Trial name
- NCT06496958
- Testing
- CO2 insufflation with an abdominal compression device, Water exchange colonoscopy
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Colo-rectal Polyps, Colonoscopy
Comparison of the Diagnostic Accuracy Between Three Dimensional and Standard Colonoscopy of Colorectal Polyps
Colorectal cancer (CRC) is one of the most common cancers worldwide. These malignancies originate in the colon or rectum, and the majority evolve from pre-existing colonic adenomas (a type of colon polyp).
- Trial name
- NCT07619248
- Testing
- 3D MonoStereo
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Colonoscopy
External, Multicentre Validation of a Machine-Learning Model to Predict Colonic Adenoma in Indian Adults
Colorectal adenomas are precursors to colorectal cancer (CRC). Accurate pre-procedure risk stratification could optimize colonoscopy yield and resource allocation in India, where adenoma prevalence varies by age, sex, and…
- Trial name
- NCT07329816
- Testing
- Not Applicable / Observational study
- Volunteers
- 1,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Oxygen Desaturation, Apnea (Central and Obstructive)
Supplemental Oxygen and Oxygen Desaturations in Colonoscopies
This study will compare apnea and oxygen desaturation events among various methods of supplemental oxygen delivery during procedural sedation in colonoscopy patients.
- Conditions
- Oxygen Desaturation, Apnea (Central and Obstructive), Airway Obstruction
- Trial name
- NCT07515755
- Testing
- Breath-synchronized oxygen, CPAP, Control
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Utah
the Difficulty of Colonoscopy Insertion
A Study on a New Indicator for Assessing the Difficulty of Colonoscopy Insertion and Its Related Factors
This study will include adult patients undergoing painless colonoscopy at our hospital. The time required for endoscope insertion to reach the cecum (Cecal Intubation Time, CIT) by physicians of different experience levels will…
- Trial name
- NCT07228715
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Second Hospital of Jilin University
HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia
Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy
The goal of this observational study is to learn how common Helicobacter pylori (H. pylori) infection is in adults without stomach or upper gastrointestinal symptoms who are having a preventive screening colonoscopy.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Intestinal Metaplasia, Barett's Esophagus
- Trial name
- G-SCOGE (NCT07346521)
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat