Clinical trials: Colonoscopy Procedures
Colorectal Cancer
An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
The primary objective is to confirm the specificity of a multi-target stool DNA test (mt-sDNA), Cologuard, in an average risk population, ages 45-49.
- Trial name
- NCT03728348
- Testing
- mt-sDNA screening test, Colonoscopy
- Where
- 39 sites in United States
- Volunteers
- 983 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colonoscopy
BLI-800-302: BLI-800 vs an Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
This is a randomized, parallel, multi-center, single-blind study, comparing BLI-800 to an FDA approved bowel preparation in adult subjects undergoing colonoscopy.
- Trial name
- NCT00503815
- Testing
- BLI-800, Polyethylene glycol 3350 based bowel preparation
- Where
- 10 sites in United States
- Volunteers
- 360 people
- Sponsor
- Braintree Laboratories
Colonoscopy
F38-27: An Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To compare the safety and efficacy of 2 different bowel cleansing preparations prior to colonoscopy in adult subjects.
- Trial name
- NCT00857272
- Testing
- PEG electrolyte lavage solution + bisacodyl - reformulation, PEG electrolyte lavage solution + bisacodyl
- Where
- 6 sites in United States
- Volunteers
- 308 people
- Sponsor
- Braintree Laboratories
Bowel Preparation
Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
Bowel preparation for pediatric colonoscopy.
- Trial name
- PICCOLO (NCT04113382)
- Testing
- CLENPIQ, MIRALAX, SENNA
- Where
- 4 sites in United States
- Volunteers
- 39 people
- Sponsor
- Ferring Pharmaceuticals
Pain, Cancer
A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy
GIC-1001 is a novel, orally-administered, colonic analgesic drug developed as an alternative to i.v. sedation during full colonoscopy.
- Conditions
- Pain, Cancer, Colonic Diseases
- Trial name
- NCT01926444
- Testing
- GIC-1001
- Where
- 15 sites in United States, Canada
- Volunteers
- 308 people
- Sponsor
- gicare Pharma Inc.
Diagnosis Disease
Efficacy, Safety and Tolerability of a New Bowel Cleansing Preparation (BLI800) in Adult Subjects Undergoing Colonoscopy
The purpose is to demonstrate that BLI800 is non-inferior, on overall colon cleansing, to Fortrans® (a reference colonic lavage in China) administered in adult subjects scheduled to undergo a colonoscopy for a routinely accepted…
- Trial name
- EASY (NCT03562884)
- Testing
- BLI800, Fortrans®
- Where
- 10 sites in China
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Ipsen
Adenoma, Polyps
Prospective Trial to Compare ADR of G-EYE™ Colonoscopy With Standard Colonoscopy
The purpose of this study is to compare the adenoma detection rate (ADR) of the G-EYE™ colonoscopy with that of standard colonoscopy.
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT02545699
- Testing
- G-EYE™ Colonoscopy, Standard Colonoscopy
- Where
- Israel
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Neoplasms
Third Eye Panoramic Device Feasibility Evaluation
This study will evaluate the feasibility of using the Third Eye Panoramic device in conjunction with standard colonoscopes in a clinical setting.
- Trial name
- NCT02368977
- Testing
- Third Eye Panoramic device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Adenoma, Polyps
Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT01917513
- Testing
- G-EYE™ colonoscopy, Standard Colonoscopy
- Where
- 15 sites in United States, Denmark and 6 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Gastrointestinal Disease, Colorectal Cancer
Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
The primary objective of this multi-center, prospective, randomized controlled trial is to evaluate the bowel cleansing after Pure-Vu use in outpatient subjects at high risk for inadequate colon preparation as compare to standard…
- Trial name
- RESCue (NCT04285008)
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Sedation
Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy
The purpose of this dose-response study is to assess the safety and efficacy of CNS 7056 compared with midazolam to maintain suitable sedation levels in patients undergoing colonoscopy.
- Trial name
- NCT01145222
- Testing
- A. CNS 7056, B. CNS 7056, C. CNS 7056
- Where
- 9 sites in United States
- Volunteers
- 162 people
- Sponsor
- Paion UK Ltd.
Bowel Preparation
A Phase 3 Trial in Bowel Preparation for Colonoscopy
This is a prospective randomized study compared with active control arm. The investigators compare the colon cleansing in patients undergoing colonoscopy.
- Trial name
- NCT05870553
- Testing
- CTP0301-A, CTP0301-B, Cool prep
- Where
- South Korea
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Colorectal Cancer, Adenoma
Comparing Detection of Standard Colonoscopy, CAD-EYE and Combined CAD-EYE and G-EYE® Aided Colonoscopy
The purpose of this study is to compare the additional diagnostic yield over Standard Colonoscopy (i.e., the adenoma miss-rate reduction) obtained by performing CADEYE and G-EYE® aided colonoscopy, vs.
- Trial name
- NCT05237310
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy, CAD-EYE
- Where
- Germany
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Screening Colonoscopy
Use of a Colon Irrigation Device as a Preparation for a Colon Visualization Procedure
A prospective, single center, study to evaluate the effectiveness of the HyGIeaCare Prep when used in combination with the PillCam COLON; the hypothesis is that the HyGIeaCare Prep will be easier for the patients to tolerate, and…
- Trial name
- NCT03458390
- Testing
- HyGIeaCare colon irrigation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Colonoscopy
BLI800-303: An Efficacy Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To evaluate the safety and efficacy of BLI800 vs an FDA approved bowel preparation before colonoscopic examination in adult subjects.
- Trial name
- NCT00856843
- Testing
- BLI800, Polyethylene glycol 3350 based bowel preparation
- Where
- 5 sites in United States
- Volunteers
- 136 people
- Sponsor
- Braintree Laboratories
Polyp and Adenoma Detection During Colonoscopy
Polyp Detection Rate After Single Oral Dose of Methylene Blue MMX Modified Release Tablets Administered to Subjects Undergoing Outpatients Colonoscopy
Polyp detection rate in colonoscopy following oral administration of MMX methylene blue tablets
- Trial name
- NCT01520337
- Testing
- oral tablet dye for detection of polyps during colonoscopy
- Volunteers
- 170 people
- Sponsor
- Cosmo Technologies Ltd
Colon Cancer, Colon Disease
Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia
A retrospective study to evaluate the effectiveness and safety of 1L polyethylene glycol (PEG)+ Ascorbic acid given for bowel preparation before colonoscopy.
- Conditions
- Colon Cancer, Colon Disease, Colon Cleansing
- Trial name
- NCT05174845
- Testing
- 1L PEG + ASCORBIC ACID
- Where
- 12 sites in Portugal, Spain
- Volunteers
- 13,393 people
- Sponsor
- Norgine
Colon Cancer
BLI850 vs an Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
This is a randomized, parallel, multi-center, single-blind study, comparing BLI850 to an FDA approved bowel preparation in adult subjects undergoing colonoscopy.
- Trial name
- NCT00756977
- Testing
- BLI850, polyethylene glycol 3350 based bowel preparation
- Where
- 12 sites in United States
- Volunteers
- 394 people
- Sponsor
- Braintree Laboratories
Colonoscopy
Measurement of Gastric Emptying During and After COLOKIT® Intake
Ultra-sound study to assess changes in intragastric volume after bowel preparation.
- Trial name
- NCT01398098
- Testing
- Sodium phosphate
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Laboratoires Mayoly Spindler
Routine Colonoscopy
Evaluation of the Main Determinants of Patient Acceptability of the Bowel Cleansing Procedure, and of Success of Bowel Cleansing and Caecal Intubation
Several factors are important in achieving a successful colonoscopy, including patient acceptability of the bowel cleansing procedure and the overall quality of cleansing.
- Trial name
- NCT01626196
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Norgine