Clinical trials: Colonoscopy Procedures
Polyp of Colon, Colorectal Polyp
Artificial Intelligence Development for Colorectal Polyp Diagnosis
Accurate classification of growths in the large bowel (polyps) identified during colonoscopy is imperative to inform the risk of colorectal cancer.
- Trial name
- NCT06447012
- Testing
- Colonoscopy
- Where
- United Kingdom
- Volunteers
- 4,000 people
- Sponsor
- King's College Hospital NHS Trust
Dietary Modification
Efficacy and Acceptability of Low-Residue Diet Package (Enimaclin®) as Diet Control Before Colonoscopy
The purpose of this study is to evaluate the efficacy and the acceptability of low-residue diet package (Enimaclin®) as diet control before colonoscopy.
- Trial name
- NCT01665157
- Testing
- Enimaclin®, Self-controlled diet, 2L PEG-ELS
- Where
- 4 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- National Taiwan University Hospital
Sedation
A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy
-to determine if propofol sedation leads to shorter recovery times compared to traditional sedation using midazolam plus meperidine
- Trial name
- NCT00848861
- Testing
- propofol (sedation for outpatient colonoscopy), midazolam plus meperidine (sedation for outpatient colonoscopy)
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
Colorectal Adenoma
Three Arm Rand Trial of HD Light vs Reveal® Cap vs Endocuff Cap for Detection of Colorectal Adenomas (TRACE)
Protocol Title: Three Arm Prospective Randomized controlled trial of High-Definition White-light colonoscopy versus High-Definition White-light colonoscopy with Reveal® Distal Attachment Cap versus High-Definition White-light…
- Trial name
- TRACE (NCT03952611)
- Testing
- Colonoscopy, distal Cap, Endocuff
- Where
- United States
- Volunteers
- 1,203 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Polyps Colorectal, Colonoscopy
Optical Diagnosis of Neoplasia Using Artificial Intelligence
Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI.
- Conditions
- Polyps Colorectal, Colonoscopy, Optical Biopsy, Colorectal Cancer Control and Prevention
- Trial name
- FAIR (NCT07158203)
- Testing
- CADx simultaneously, CADx delayed
- Where
- 2 sites in Norway, Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Pronase, Mucosal Clarity
Pronase in Improving Endoscopic Mucosal Clarity During Colonoscopy for Patients with Colitis
Pronase is a proteolytic enzyme known for its ability to clear mucus by breaking down its main component, mucin, through enzymatic hydrolysis.
- Trial name
- NCT06874673
- Testing
- Pronase
- Where
- China
- Volunteers
- 438 people
- Sponsor
- Changhai Hospital
Bowel Cleansing Quality
Tailored Bowel Preparation According to Bristol Stool Form Scale
The Bristol stool form scale ( BSFS) based tailored bowel cleansing regimen might be helpful to improve bowel cleansing quality before colonoscopy.
- Trial name
- NCT02415569
- Testing
- Standard Bowel Prep (2L PEG-ELP), 2L PEG-ELP and 10mg bisacodyl
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Shandong University
CRC
Evaluation of the Motus GI CleanUp System During Screening Colonoscopy
Motus GI is developing a single-use device that attaches to a standard colonoscope, thereby integrating colon cleansing, screening and treatment into one procedure. The device creates turbulence within the colon using water jets.
- Trial name
- NCT01838980
- Testing
- Motus GI Clean-Up Device
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Routine Colonoscopy
Evaluation of the Main Determinants of Patient Acceptability of the Bowel Cleansing Procedure, and of Success of Bowel Cleansing and Caecal Intubation
Several factors are important in achieving a successful colonoscopy, including patient acceptability of the bowel cleansing procedure and the overall quality of cleansing.
- Trial name
- NCT01626196
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Norgine
Colorectal Polyp
The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon
Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates.
- Trial name
- NCT06186778
- Testing
- secondary colonoscopy, conventional colonoscopy
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Inflammatory Bowel Diseases, Colonic Neoplasms
IBD Neoplasia Surveillance Pilot RCT
To determine if random biopsies can be safely eliminated from screening of average risk persons with IBD, the investigators propose to carry out a pilot randomized control trial in which targeted biopsies in combination with…
- Conditions
- Inflammatory Bowel Diseases, Colonic Neoplasms, Dysplasia
- Trial name
- IBDDysplasia (NCT04067778)
- Testing
- Intervention Group, Control Group
- Where
- 12 sites in Canada
- Volunteers
- 600 people
- Sponsor
- Ottawa Hospital Research Institute
Advanced Colorectal Cancer, Colo-rectal Cancer
Optimal Surveillance Strategy After Positive FIT and Negative Colonoscopy
Individuals with high fecal hemoglobin concentrations detected by fecal immunochemical testing (FIT) but negative findings on high-quality colonoscopy represent a clinically challenging population.
- Conditions
- Advanced Colorectal Cancer, Colo-rectal Cancer, Fecal Immunochemical Test
- Trial name
- NCT07470658
- Testing
- Colonoscopy Surveillance
- Where
- Taiwan
- Volunteers
- 1,274 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colonoscopy
Music Utilization in Sedation and Induction in Colonoscopy
Conscious sedation (CS) if often used in the field of gastroenterology to alleviate pain and discomfort with interventional procedures.
- Trial name
- MUSIC (NCT04468048)
- Testing
- Music: "Nada Himalaya" performed by S. G. Sachchidananda
- Where
- United States
- Sponsor
- The Brooklyn Hospital Center
Mesothelioma
A Single Dose FMT Infusion as an Adjunct to Keytruda for Metastatic Mesothelioma
The investigators propose to ensure a favorable gut microbiome by fecal microbiota transplant to enhance the efficacy Keytruda
- Trial name
- NCT04056026
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- ProgenaBiome
Cognitive Dysfunction
The Effect of Physostigmine on Cognitive Functioning in the Immediate Period After Sedation for Colonoscopy
The purpose of this study is to determine whether the administration of physostigmine in combination with sedation for colonoscopy can minimize the cognitive decline at the time of hospital discharge
- Trial name
- NCT01121497
- Testing
- Physostigmine
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Rabin Medical Center
Bowel Preparation
Bowel Preparation by Face-to-face Re-education on the Day of Colonoscopy for Outpatient: a RCT
The study compares the efficacy of bowel preparation between the face-to-face re-education(FFRE group) and normal education (no-FFRE group) in patients.
- Trial name
- FFRE (NCT02772250)
- Testing
- telephone re-education(TRE), face-to-face re-education (FFRE)
- Where
- China
- Volunteers
- 658 people
- Sponsor
- Shandong University
Colorectal Adenoma
Colorectal Neoplasia Screening w Colonoscopy in Asymptomatic Women at Regional Navy/Army Medical Ctrs: The CONCeRN Trial
The CONCeRN Trial is a multi-center study of asymptomatic women between the ages of 40 and 75 referred to regional military medical centers for routine colorectal screening.
- Trial name
- NCT00339950
- Where
- 3 sites in United States
- Volunteers
- 937 people
- Sponsor
- National Cancer Institute (NCI)
Lactulose, Bowel Preparation
Clinical Study on the Application of Lactulose Combined with Linaclotide in Bowel Preparation for Colonoscopy
This is a single-center, single-blind, randomized controlled clinical study. Participants meeting the inclusion criteria were randomly assigned to lactulose + linaclotide group, lactulose group, and PEG group in equal proportion.
- Trial name
- NCT06748638
- Testing
- Lactulose, Lactulose+ linaclotide, polyethylene glycol (PEG)
- Where
- China
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Haifeng Lan
Complication of Injection, Pain
Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol
The purpose of this study is to compare the incidence and intensity of possible pain on injection as well as patient satisfaction caused by propofol (a lipid based medication); Lusedra (a water based medication); and the drug…
- Trial name
- NCT01401049
- Testing
- Fospropofol, Propofol/Lidocaine
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- NYU Langone Health
Colorectal Cancer
I-Scan Vs High Definition White Light (Main Study)
The purpose of this study is to assess whether the use of I-Scan during colonoscopy leads to an increased yield of adenomas in the colon among a population at increased risk for CRC.
- Trial name
- NCT02016326
- Testing
- HD Colon, I-scan 1, I-Scan 2
- Where
- Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Calgary
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