Clinical trials: Colonoscopy Procedures
Bowel Preparation, Colonoscopy
Bowel Preparation for Colonoscopy in the Elderly
The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce.
- Trial name
- NCT02290093
- Testing
- Standard full-volume PEG, Split-dose full-volume PEG, Split-dose low-volume PEG
- Where
- 3 sites in South Korea
- Volunteers
- 230 people
- Sponsor
- Kyunghee University Medical Center
PARKINSON DISEASE (Disorder), Parkinson
Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis
The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease.
- Conditions
- PARKINSON DISEASE (Disorder), Parkinson, Parkinson's Disease and Parkinsonism, Parkinson Disease
- Trial name
- Syn-G (NCT07204652)
- Testing
- No Intervention: Observational Cohort
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CND Life Sciences
Artificial Intelligence
Using AI-assisted Optical Polyp Diagnosis for Diminutive Colorectal Polyps
This is a prospective study that is the first to implement resect and discard and diagnose and leave strategies in real-time practice using stringent documentation and adjudication by 2 expert endoscopists as the gold standard.
- Trial name
- AI-OD (NCT06059378)
- Testing
- Artificial intelligence-assisted classification (CADx)
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Sessile Serrated Adenoma
Prediction of Dysplasia Within Sessile Serrated Polyps Using Endoscopic Imaging; a Prospective Observational Study
Study of endoscopic imaging in the detection of dysplasia within serrated colonic lesions >= 8mm in size
- Trial name
- SERRESH (NCT03100552)
- Testing
- Endoscopic imaging
- Where
- Australia
- Volunteers
- 86 people
- Sponsor
- Western Sydney Local Health District
Gastrointestinal Diseases, Colorectal Cancer
Optimizing the Preparation Regime Prior to Colonoscopy Procedure With Pure-Vu System
The primary objective of this multicenter, prospective, randomized study is to evaluate the performance of Pure-Vu System in cleansing patients' colon who are indicated for a colonoscopy procedure using one of two different…
- Trial name
- NCT03493009
- Testing
- Pure-Vu System
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Colorectal Cancer, Adenoma
G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate-randomized Tandem Study With Different Endoscopist
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy.
- Trial name
- NCT02066064
- Testing
- Standard Colonoscopy, G-EYE(TM) Colonoscopy
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colonoscopy, Adjunct Anesthesia Medication
Diphenhydramine as an Adjunctive Sedative in Patients on Chronic Opioids
To access the efficacy of adding diphenhydramine as adjunct to improve sedation and to reduce the amount of standard sedatives used during colonoscopy in patients on chronic opioids.
- Trial name
- NCT01967433
- Testing
- Diphenhydramine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Oklahoma
Colorectal Disorders, Colorectal Neoplasms
Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position.
- Conditions
- Colorectal Disorders, Colorectal Neoplasms, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- NCT07517848
- Testing
- Colonoscopy after bowel cleansing
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Colorectal Cancer
Real-Time Characterizations of Diminutive Colorectal Polyps Using Narrow Band Imaging
Colorectal cancer is the second leading cause of cancer related death in the United States. Colonoscopy is the most commonly performed screening procedure and diminutive polyps (<5mm) are the most commonly found polyps during…
- Trial name
- NCT02441998
- Testing
- Education intervention: Training in Narrow Band Imaging
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Colorectal Canceer
Usefulness of Endocuff in the Adenoma Detection Rate. Comparative Study
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. The cumulative risk of developing CRC is about 6% lifelong.
- Trial name
- NCT02387593
- Testing
- ENDOCUFF
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Cleansing Quality of the Colon
Impact of Low Fiber Diet on Colonic Cleansing Quality (DIETPREP)
This is a single center randomized controlled trial to compare bowel cleansing for outpatient colonoscopy in two groups of participants: one group will receive instructions of one-day structured low fiber diet whilst the other…
- Trial name
- DIETPREP (NCT03247452)
- Testing
- One-day Low fiber diet, Three-day low fiber diet, Polyethylene Glycol plus ascorbic acid
- Where
- Spain
- Volunteers
- 404 people
- Sponsor
- Hospital Universitario de Canarias
Digestive System Diseases
Confocal Laser Endomicroscopy
Confocal laser endomicroscopy (CLE) is a new diagnostic technique that allows microscopic examination of the digestive mucosa during ongoing endoscopy.
- Trial name
- NCT00561938
- Testing
- Colonoscopy, Endoscopy
- Where
- 5 sites in France
- Volunteers
- 61 people
- Sponsor
- Nantes University Hospital
IBD (Inflammatory Bowel Disease), Colonoscopy
Pre-packaged Low-residue Diet for Bowel Preparation in Patients With Inflammatory Bowel Disease
The primary objectives of this project are twofold: firstly, to evaluate the role of Maifu Changqing® Complete Nutrition Formula Powder in bowel preparation for colonoscopy in patients with IBD; and secondly, to enhance the…
- Conditions
- IBD (Inflammatory Bowel Disease), Colonoscopy, Colonoscopy: Bowel Preparation
- Trial name
- NCT07353853
- Testing
- pre-packaged low-residue diet for bowel preparation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Colon Polyp, Adenoma
Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection
The study will compare the use of a 6-month follow-up vs a 12-month follow-up after the removal of a large non-pedunculated polyp 20-50mm in size and without high grade dysplasia.
- Conditions
- Colon Polyp, Adenoma, Serrated Polyp, Recurrence, Local Neoplasm
- Trial name
- STARLING (NCT07198945)
- Testing
- 6-month follow-up, 12-month follow-up
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 546 people
- Sponsor
- Indiana University
Colonoscopy Preparation
Comparison of Bowel Cleansing Regimens for Colonoscopy
Colonoscopy is a frequently used method in colon cancer screening today. Routine bowel cleansing is performed for colonoscopy. When the guidelines are examined, there are various recommendations regarding colonoscopy preparation…
- Trial name
- NCT06021639
- Testing
- The last 24 hours will consume low fiber food.
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Mersin University
Colonic Irrigation
Feasibility and Effectiveness of Colonic Irrigation
This study will allow investigators to determine whether colonic irrigation may allow for a non-oral, same-day alternative to traditional oral bowel prep regimens.
- Trial name
- NCT02826967
- Testing
- Colonic Irrigation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Adenomatous Polyps
Complete Histologic Resection of Adenomatous Polyps?
Colorectal cancer is the second most common cause of cancer death in the US. Colonoscopy is considered the best test colorectal cancer screening.
- Trial name
- CARE (NCT01224444)
- Testing
- standard polypectomy snare
- Where
- 2 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- White River Junction Veterans Affairs Medical Center
Endoscopy, Colonoscopy
Can Nitrous Oxide (Laughing Gas) be Used as a Sedative for GI Endoscopy Procedures?
Nitrous oxide (commonly known as 'laughing gas') is often used during dental and other outpatient procedures, because it is easy to administer, is short-acting and rapidly clears from the body following the procedure.
- Trial name
- NCT05396144
- Testing
- 5% inhaled nitrous oxide, 50% inhaled nitrous oxide
- Where
- United States
- Sponsor
- Stanford University
Colonoscopy Preparation
2 Regimens of Lactulose for Colonoscopy Preparation in Adults
The purpose of the study is to determine the efficacy of 2 regimens of lactulose as a preparation for colonoscopy.
- Trial name
- NCT01887470
- Testing
- Full dose preparation, Split dose preparation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Colorectal Polyp, Colorectal Cancer
Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable
Colorectal cancer is prevented by colonoscopy and polypectomy. Failure to recognize the endoscopic resection scar after Endoscopic Mucosal Resection (EMR) risks unrecognized recurrent or residual adenoma (RRA), which may…
- Trial name
- SCAR (NCT06193356)
- Testing
- Learning tool
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
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