Clinical trials: Colonoscopy Procedures
Colorectal Cancer, Healthy
Computerized Feedback in Colonoscopy
In a cluster-randomized study compare if feedback from two computerized feedback systems doing a colonoscopy (CoPS and CoRS) can improve the adenoma detection rate and decrease patient discomfort.
- Trial name
- NCT04862793
- Testing
- Colonoscopy Progression Score (CoPS), Colonoscopy Retraction Score (CoRS)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Bowel Preparation
Clinical Study of Bowel Preparation Before Colonoscopy
This study was a single-center, randomized controlled clinical study. Subjects meeting the inclusion criteria will be randomly assigned to magnesium sodium potassium sulfate oral concentrated solution group, magnesium sodium…
- Trial name
- NCT06091735
- Testing
- OSS, OSS+Linzess, PEG-Interferon Alfa
- Where
- China
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Residual Gastric Contents, Polyethylene Glycol
Effect of Miralax NPO Time on Residual Gastric Volumes and Bowel Preparation
The goal of this clinical trial is to assess differences in residual gastric volumes after stopping Miralax ingestion at different time points (2, 4, 6 hours) prior to anesthesia induction and compare it to the control (current…
- Trial name
- NCT07616908
- Testing
- Stopping Miralax ingestion 4 hours prior to anesthesia induction, Stopping Miralax ingestion 6 hours prior to anesthesia induction, Stopping Miralax ingestion 2 hours prior to anesthesia induction
- Volunteers
- 200 people
- Sponsor
- Stanford University
Bowel Preparation
Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation
In order to analyze the effectiveness and patient tolerance of the two bowel preparation regimens, the investigators will compare prepackaged semisolid nutritional formulations and restricted diet.
- Trial name
- NCT04776733
- Testing
- prepackaged semisolid nutritional formulations, restricted diet
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Ningbo No. 1 Hospital
Colonoscopy
MoviPrep® Versus HalfLytely®, Low-VolUme PEG Solutions for Colon Cleansing: An InvesTigator-blindEd, Randomized, Trial
A properly prepared colon is vital to the success of any colonoscopy. The purpose of this study is to determine which colon prep, MoviPrep or HalfLytely is the superior prepping agent.
- Trial name
- LUSTER (NCT00779649)
- Testing
- MoviPrep Kit, HalfLytely and Bisacodyl Tablets Bowel Prep Kit
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Adenoma, Colonoscopy
Effect of Two Colonoscopy AI Systems for Colon Polyp Detection
Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate
- Conditions
- Adenoma, Colonoscopy, Sessile Serrated Adenoma
- Trial name
- NCT05089071
- Testing
- Assist by artificial intelligence system for colon polyp detection
- Where
- South Korea
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colonoscopy
Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures
Colonoscopy is the most useful exam used to evaluate colorectal diseases, like colorectal polyps and cancer. The appropriate bowel preparation is indispensable for colonoscopy procedures.
- Trial name
- NCT05076799
- Testing
- 100 ml lactulose combined with 1 L PEG, 100 ml lactulose combined with 2 L PEG, 200 ml lactulose
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Colorectal Carcinoma
Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps
This clinical trial tests a multilevel intervention at the clinic, provider and patient levels, to improve colonoscopy surveillance in patients with high risk colon polyps.
- Trial name
- NCT06376565
- Testing
- Best Practice, Communication Intervention, Interview
- Where
- United States
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Electroencephalography, Propofol
Values of Enhanced Monitoring by EEG Recording (Narcotrend) for Sedation in Colonoscopy
Endoscopic examinations and particularly long-lasting interventions can be uncomfortable for patients. Pain and vasovagal reactions are common.
- Conditions
- Electroencephalography, Propofol, Gender Identity
- Trial name
- NCT02687568
- Testing
- EEG monitoring
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ruhr University of Bochum
Inflammatory Bowel Diseases, Colon Dysplasia
High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
Inflammatory Bowel Disease (IBD) involving the colon is a known risk for colon cancer. There are two standards-of-care colonoscopy techniques used for screening all patients who suffer from IBD for more than eight years.
- Conditions
- Inflammatory Bowel Diseases, Colon Dysplasia, Ulcerative Colitis, Crohn Colitis
- Trial name
- NCT04191655
- Testing
- High Definition Colonoscopy, Dye Spraying Chromocolonoscopy
- Where
- 2 sites in United States
- Volunteers
- 211 people
- Sponsor
- Beth Israel Deaconess Medical Center
Sedation or Anesthesia
A Phase III Study Evaluating The Efficacy and Safety of HSK3486 for Sedation or Anesthesia
This is a Phase III, randomized, double-blind, propofol-controlled, parallel-design, multi-center study to evaluate the efficacy and safety of HSK3486 for sedation or anesthesia in patients undergoing colonoscopy and gastroscopy.
- Trial name
- NCT03674008
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Gastrointestinal Diseases
A Personalised Approach Utilising the Frailty Index to Empower Consumers
Frailty is a common clinical syndrome in older adults that may carry an increased risk for poor health outcomes including falls, hospitalisation, and mortality.
- Trial name
- NCT05292989
- Testing
- Frailty Assessment, Standard Care
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Colorectal Cancer
Fluorescent Probe VGT-309 to ID Cancerous Colorectal Lesions During Augmented Colonoscopy
The purpose of this study is to determine the safety and feasibility of VGT-309 for the visualization of colorectal tumors in real-time using near-infrared (NIR) fluorescence endoscopy.
- Trial name
- NCT06034197
- Testing
- VGT-309
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stephan Rogalla
Bleeding After GI Endoscopy
Bleeding Rate After EGD and Colonoscopy in Patients Who Continue to Take Antithrombotic Agents
The bleeding rate of both EGD (including biopsy) and colonoscopy (including biopsy, cold or hot snare polypectomy, or EMR) in patients who continue to take various antithrombotic drugs is studied prospectively.
- Trial name
- EGD (NCT02594813)
- Testing
- Biopsy, cold or hot snare polypectomy, or EMR
- Where
- Japan
- Volunteers
- 10,000 people
- Sponsor
- Showa Inan General Hospital
Colonic Polyp, Colon Lesion
Comparative Analysis of AI Software for Enhanced Polyp Detection and Diagnosis
Purpose \& Research Questions The purpose of this study is to evaluate whether artificial intelligence (AI) improves the detection of polyps and whether the system can classify the type and severity of detected changes.
- Trial name
- NCT06077435
- Testing
- AI
- Where
- Sweden
- Volunteers
- 915 people
- Sponsor
- Sahlgrenska University Hospital
Colonoscopy
Visualization of the Colon Through Use of the Magnetic Flexible Endoscope (MFE)
In this study, the investigators will evaluate the ability of the Magnetic Flexible Endoscope (MFE) to travel through the human colon.
- Trial name
- NCT05833789
- Testing
- Magnetic Flexible Endoscope (MFE)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Vanderbilt University Medical Center
Colonoscopy
Efficacy, Safety and Tolerability of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
The purpose o this study is to evaluate the safety, tolerance and efficacy of BLI800 as a bowel preparation prior to colonoscopy in pediatric patients.
- Trial name
- NCT02189850
- Testing
- BLI800 - Dose 1, BLI800 - Dose 2
- Where
- 5 sites in United States
- Volunteers
- 29 people
- Sponsor
- Braintree Laboratories
Apnea, Hypoxia
High Flow Nasal Oxygen Therapy Undergoing Colonoscopy
Investigation of the Clinical Efficacy of High Flow Nasal Oxygen in Patients Over 60 Years of Age Undergoing Colonoscopy
- Trial name
- NCT05396274
- Testing
- High Flow Nasal Cannula
- Volunteers
- 70 people
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Postoperative Hypoxemia
Effect of Different Body Positions on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and Colonoscopy
Through a multicenter, three-arm randomized controlled trial design, this study aimed to compare the effects of three positioning strategies-side-lying with elevated head position, supine with elevated head position, and standard…
- Trial name
- NCT07587970
- Testing
- lateral decubitus head-up position (LH group), supine head-up position (SH group), standard lateral decubitus position group (SL group)
- Where
- China
- Volunteers
- 1,617 people
- Sponsor
- General Hospital of Ningxia Medical University
Colorectal Neoplasms
Third Eye Panoramic Device Feasibility Evaluation
This study will evaluate the feasibility of using the Third Eye Panoramic device in conjunction with standard colonoscopes in a clinical setting.
- Trial name
- NCT02368977
- Testing
- Third Eye Panoramic device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
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