Clinical trials: Colorectal Cancer (CRC)
Metastatic Colorectal Cancer
Study of TLBZT Based Herbal Therapy Plus Chemotherapy for Metastatic Colorectal Cancer
Teng-Long-Bu-Zhong-Tang (TLBZT) is a modern anti-cancer herbal formula. Experimental studies have confirmed the anti-cancer potential of TLBZT against colorectal cancer.
- Trial name
- NCT01975454
- Testing
- Chemotherapy, Herbal therapy
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Colorectal Cancer
U01 CRC Project for Vietnamese Americans
Colorectal cancer (CRC) is the second most commonly diagnosed cancer and the third highest cause of mortality in Vietnamese and Asian Americans.
- Trial name
- NCT03413605
- Testing
- A Multilevel CBPR Intervention
- Where
- 2 sites in United States
- Volunteers
- 801 people
- Sponsor
- Temple University
Colorectal Cancer
Effect of Multimodal Prehabilitation After Colorectal Cancer Surgery
The process of enhancing an individual's functional capacity to optimize physiologic reserves before an operation to withstand the stress of surgery has been coined prehabilitation.
- Trial name
- NCT05854394
- Testing
- Multimodal prehabilitation management Multimodal prehabilitation management
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xiamen University
Cognition, Fatigue
Cognitive Function and Fatigue in Colorectal Cancer (CRC) Patients After Chemotherapy
This is a prospective, longitudinal cohort study to evaluate fatigue and cognitive function in patients with colorectal cancer (CRC) treated with chemotherapy, and in patients with the same malignancy, that do not receive…
- Conditions
- Cognition, Fatigue, Colorectal Neoplasm
- Trial name
- NCT00188331
- Testing
- Neuropsychological Testing
- Where
- 2 sites in Australia, Canada
- Volunteers
- 441 people
- Sponsor
- University Health Network, Toronto
Colorectal Cancer
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy
RATIONALE: Drugs used in chemotherapy, such as irinotecan hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT01079780
- Testing
- cetuximab, ramucirumab, irinotecan hydrochloride
- Where
- 255 sites in United States
- Volunteers
- 136 people
- Sponsor
- Eastern Cooperative Oncology Group
Colorectal Cancer
Acupuncture for Enhanced Recovery After Surgery in Patients Undergoing Laparoscopic Colorectal Cancer Resection
Background: Patients who undergo laparoscopic surgical resection of colorectal cancer may experience various post-operative symptoms (e.g., pain, nausea and vomiting, and anxiety) and limitation of daily activities (e.g., walking…
- Trial name
- NCT02388256
- Testing
- acupuncture, early recovery program after surgery
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Colorectal Cancer
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581
This research trial studies tissue samples from patients with stage II colon cancer treated on Cancer and Leukemia Group B (CALGB)-9581 or CALGB-90903.
- Trial name
- NCT00897429
- Testing
- laboratory biomarker analysis
- Where
- United States
- Volunteers
- 2,059 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colorectal Cancer Metastatic
A Clinical Study of T3011 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer
This is a phase I, open-label clinical study of T3011 in combination with Toraplizumab and Regorafenib in patients with liver metastases from colorectal cancer.
- Trial name
- NCT06283303
- Testing
- T3011 hepatic artery infusion, toripalimab, regorafenib
- Volunteers
- 8 people
- Sponsor
- China Medical University, China
Colorectal Cancer, Shared Decision Making
Preoperative 3D Models and Shared Decision-making
The objectives of this study will be to quantify, using validated scales, the effects of 3D-printed models on shared decision-making and patient anxiety during the pre-operative consent and education process.
- Conditions
- Colorectal Cancer, Shared Decision Making, Anxiety, Informed Consent
- Trial name
- NCT06625008
- Testing
- 3D-printed model
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Vanderbilt University Medical Center
Colorectal Adenoma, Colorectal Carcinoma
Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma
This phase IIa trial studies how well aspirin works in preventing colorectal cancer in patients with colorectal adenoma. Aspirin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT02965703
- Testing
- Aspirin, Biospecimen Collection, Questionnaire Administration
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- National Cancer Institute (NCI)
Sarcoma, Carcinoma
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Solid Tumors
20 participants are expected to be enrolled for this open，Single-armed clinical trial to evaluate the safety and efficacy of the recombinant herpes simplex virus Ⅰ, R130 in patients with advanced solid tumors.
- Conditions
- Sarcoma, Carcinoma, Breast Cancer, Pancreatic Cancer
- Trial name
- NCT05860374
- Testing
- Recombinant oncolytic herpes simplex virus type 1 (R130)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Yunying Medical Technology
Dysplasia in IBD
Dysplasia in Inflammatory Chronic Idiopathic Colitis Long-standing
Chronic intestinal inflammation produce dysplasia more frequently than the normal population. The therapies protect against these changes, but do not rule out dysplasia.
- Trial name
- NCT03096717
- Testing
- colonoscopy and histology
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Prostate Cancer
Cultured Circulating Tumor Cells in Prostate and Other Cancers
The purpose of this study is to evaluate the number of circulating tumor cells (CTC) before and after treatment using an experimental method for detecting CTC, compared to commercial CTC assay results, in patients with prostate…
- Trial name
- NCT02123862
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Oscar Goodman, Jr.
Colorectal Cancer, Pancreatic Adenocarcinoma
Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma
The purpose of this research study to find out if the drug trametinib in combination with ruxolitinib is safe, tolerable and has beneficial effects in people who has certain type of cancers including the type that you have.
- Trial name
- NCT04303403
- Testing
- Trametinib, Ruxolitinib
- Where
- Singapore
- Volunteers
- 48 people
- Sponsor
- National Cancer Centre, Singapore
Colorectal Cancer, Surgery
Cardiopulmonary Exercise Test Data Averaging Methods and Preoperative Risk Assessment
Cardiopulmonary exercise testing (CPET) is used for preoperative risk assessment in patients with colorectal cancer who need to undergo surgery.
- Conditions
- Colorectal Cancer, Surgery, Colorectal Neoplasms Malignant
- Trial name
- NCT05353127
- Testing
- CPET/Cardiopulmonary Exercise Test
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- VieCuri Medical Centre
Colorectal Neoplasms
Locally Advanced Colorectal Cancer and Local Recurrences in Västra Götaland
The aim of this study is to review the treatment strategies of locally advanced colorectal cancer and locally recurrent rectal cancer in Västra Götaland during 1995-2016.
- Trial name
- NCT04406974
- Testing
- Surgery or treatment for local recurrence, Surgery for advanced colorectal cancer
- Where
- Sweden
- Volunteers
- 4,000 people
- Sponsor
- Sahlgrenska University Hospital
Advanced Cancer
Outcomes of Triaged Family Care in Advanced Cancer
The purpose of this study is to assess the quality of life of patients with advanced cancer and their family caregivers and to evaluate two doses of a family-based program of care versus control.
- Trial name
- FOCUS-Triage (NCT00709176)
- Testing
- Brief FOCUS Program, Extensive FOCUS Program
- Where
- 5 sites in United States
- Volunteers
- 484 people
- Sponsor
- University of Michigan
Bladder Cancer, Breast Cancer
Exercise in Improving Mobility and Reducing Fatigue and/or Weakness in Older Cancer Survivors
RATIONALE: Exercise may help improve mobility and relieve fatigue and/or weakness in cancer survivors. It is not yet known whether exercise is more effective than standard therapy in improving mobility and reducing fatigue and/or…
- Conditions
- Bladder Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer
- Trial name
- NCT00335491
- Testing
- exercise intervention, complementary or alternative medicine procedure, fatigue assessment and management
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Utah
Colorectal Cancer Metastatic
Raman Spectroscopy for Liver Tumours Following Liver Surgery
The aim of the proposed research is to develop a quick and reliable method for automated evaluation of tissue sections for residual tumour in histology specimens following liver surgery.
- Trial name
- NCT05995990
- Testing
- Raman Spectrometry
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Colorectal Cancer
Exploratory Study of Intermittent Hypoxia Intervention on Colorectal Cancer
This study aims to explore the safety and efficacy of intermittent hypoxia intervention on patients with colorectal cancer.
- Trial name
- NCT06584318
- Testing
- Intermittent hypoxia intervention
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University