Clinical trials: Colorectal Diseases
Colonic Neoplasms, Rectal Neoplasms
The Effect of Case Management in Complex Cancer Pathways
Introduction: Case management (CM) has been proposed as a method for optimizing the course of treatment for complicated cancer patients.
- Trial name
- NCT00845247
- Testing
- Nurse case management
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- University of Aarhus
Colorectal Cancer
Surgical Prehabilitation of Cancer Patients Undergoing Colorectal Resection.
Psychological distress is common among adults newly diagnosed with cancer and those awaiting cancer treatment(s). Although preoperative psychological distress has been shown to be associated with poorer physical health and…
- Trial name
- NCT04248647
- Testing
- Multimodal prehabilitation
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cancer, Solid Tumor
Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA
Solid tumors pose significant challenges in current therapeutic approaches. Targeted therapy has emerged as a promising avenue, aiming to enhance treatment efficacy while minimizing adverse effects.
- Conditions
- Cancer, Solid Tumor, Colorectal Cancer, Breast Cancer
- Trial name
- PTST_PALBEVA (NCT06307249)
- Testing
- SNP, Palbociclib 125mg, Bevacizumab
- Where
- 2 sites in Lebanon
- Volunteers
- 50 people
- Sponsor
- Lebanese University
Neoplasm of Rectum, Surgery--Complications
Validation of Low Anterior Resection Syndrome Score in Korean Version
In contemporary era of rectal cancer treatment, development of surgical technique and tool, adaptation of chemoradiation therapy, as well as multidisciplinary approach have led increased survival as well as rate of sphincter…
- Conditions
- Neoplasm of Rectum, Surgery--Complications, Surgery
- Trial name
- NCT03211715
- Testing
- questionnaire
- Volunteers
- 300 people
- Sponsor
- Saint Vincent's Hospital, Korea
Colon Cancer, Precancerous Condition
Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia
This randomized phase II trial is studying atorvastatin calcium to see how well it works compared to oligofructose-enriched inulin, sulindac, or a placebo in preventing cancer in patients at increased risk of developing…
- Conditions
- Colon Cancer, Precancerous Condition, Rectal Cancer
- Trial name
- NCT00335504
- Testing
- oligofructose-enriched inulin, sulindac, atorvastatin calcium
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Cancer Institute (NCI)
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Rectal Cancer
Short Term Outcomes of Robotic-assisted Intersphincteric Resection for Low Rectal Cancer
This study compared robot-assisted total mesorectal excision to treat very low rectal cancer within 2 cm from the dentate line to avoid permanent colostomy.
- Trial name
- R-ISR (NCT03597126)
- Testing
- Robot-assisted surgery, Laparoscopic surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Southwest Hospital, China
Colorectal Cancer, Colorectal Surgery
Assessing the Feasibility of Using Methylene Blue in Identifying Ureters During Colorectal Surgery
This study will assess whether methylene blue fluorescence imaging can help surgeons identify the ureters during colorectal surgery.
- Conditions
- Colorectal Cancer, Colorectal Surgery, Ureteric Injury
- Trial name
- NCT07861815
- Testing
- Intravenous Methylene Blue, Methylene Blue Fluorescence Imaging System
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Rectal Cancer
Sigmoid Take-off, New Rectum Definition
The diversity of definitions for the rectosigmoid junction is becoming a major obstacle to the standardization of optimal treatment of rectal cancers.
- Trial name
- NCT04293835
- Testing
- Whether to have intestinal-related disease
- Where
- China
- Volunteers
- 835 people
- Sponsor
- Peking University Third Hospital
Early Gastric Cancer, Colon Neoplasia
Magnetic Guided Counetrtraction During Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) is a technique that allows curative treatment of early gastrointestinal neoplasia with organ preservation. However, it is a technically demanding procedure.
- Trial name
- NCT06962293
- Testing
- MAG-ESD assisted ESD
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer
Nitrous Oxide and Risk of Cancer Recurrence After Colorectal Surgery: A Randomized, Blinded Study
This study was developed to test the hypothesis that the risk of colorectal cancer recurrence was similar in patients who were randomly assigned to 65% nitrous oxide or nitrogen during colorectal surgery.
- Trial name
- NCT00781352
- Testing
- nitrous oxide, nitrogen
- Where
- Austria
- Volunteers
- 408 people
- Sponsor
- The Cleveland Clinic
Colorectal Disorders
Robotic Assisted Colon and Rectal Surgery Prognostic and Outcome Analysis
To analysis surgical outcome between robotic and laparoscopy colon and rectal surgery. Retrospective case-control study of single institute.
- Trial name
- NCT05210647
- Testing
- robotic surgery
- Where
- Taiwan
- Volunteers
- 291 people
- Sponsor
- Taichung Veterans General Hospital
Metastatic Colorectal Cancer
Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer
The primary purpose of this study is to evaluate the clinical response and safety of CMAB009 plus irinotecan versus irinotecan-only as second-line treatment after fluoropyrimidine and oxaliplatin failure in KRAS wild-type…
- Trial name
- CRC009 (NCT01550055)
- Testing
- CMAB009 plus Irinotecan, Irinotecan-only and sequential-CMAB009
- Volunteers
- 512 people
- Sponsor
- Shanghai Zhangjiang Biotechnology Limited Company
Colorectal Neoplasms, Colorectal Polyp
Virtual Reality Colonoscopy : a Study From Nancy
Colonoscopy is an exam which can be responsible for pain and discomfort for the patient. Therefore colonoscopy is performed most of the time under general anaesthesia.
- Trial name
- NCT05203978
- Testing
- colonoscopy
- Volunteers
- 120 people
- Sponsor
- Central Hospital, Nancy, France
Advanced Colon Adenocarcinoma, Advanced Colorectal Adenocarcinoma
Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer
This phase II trial studies how well the combination of botensilimab, balstilimab and regorafenib works compared to botensilimab and balstilimab in treating patients with microsatellite stable colorectal cancer that may have…
- Conditions
- Advanced Colon Adenocarcinoma, Advanced Colorectal Adenocarcinoma, Advanced Rectal Adenocarcinoma, Metastatic Colon Adenocarcinoma
- Trial name
- NCT06575725
- Testing
- Balstilimab, Biopsy, Biospecimen Collection
- Sponsor
- City of Hope Medical Center
Colorectal Cancer
Avastin/FOLFIRI in Combination With Curcumin in Colorectal Cancer Patients With Unresectable Metastasis
Oral curcumin-containing supplement will be given to colorectal cancer patients with unresectable metastases who will be starting Avastin/FOLFIRI chemotherapy for up to completion of (or withdrawal from) chemotherapy.
- Trial name
- NCT02439385
- Testing
- Avastin/FOLFIRI, Curcumin
- Volunteers
- 44 people
- Sponsor
- Gachon University Gil Medical Center
Colorectal Neoplasms
Low-dose Capecitabine Adjuvant Chemotherapy for Elderly Patients With Stage II/III Colorectal Cancer
Approximately half of colorectal cancer (CRC) patients were first diagnosed after 70 years old. However, compared with younger patients, elderly patients were often undertreated in chemotherapy due to their impaired tolerance.
- Trial name
- LcACEC (NCT02316535)
- Testing
- Capecitabine
- Where
- China
- Volunteers
- 710 people
- Sponsor
- West China Hospital
Cancer Colorectal, Frailty
Digital Home-Based Prehabilitation Before Surgery
This clinical trial compares two different prehabilitation programs, with no organized prehabilitation, prior to major colorectal cancer surgery.
- Conditions
- Cancer Colorectal, Frailty, Surgery
- Trial name
- dHOPE (NCT06231576)
- Testing
- Prehabilitation
- Volunteers
- 140 people
- Sponsor
- Vestre Viken Hospital Trust
Colorectal Cancer, Mobile Phone Use
Investigation of the Effect of Training on the Side Effects of Chemotherapy Given Via the Mobile Health Application on the Quality of Life in Colorectal Cancer Patients
The incidence of colorectal cancer ranks fourth worldwide after lung, prostate and breast cancers. Although chemotherapy has an important place in the treatment of colorectal cancers, it can cause side effects such as diarrhea…
- Conditions
- Colorectal Cancer, Mobile Phone Use, Nurse's Role
- Trial name
- NCT05940740
- Testing
- Colorectal-Mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- NESLISAH YASAR KARTAL
Colorectal Cancer, Adenocarcinoma of the Colon
A Study of Trastuzumab Deruxtecan (T-DXd) and Cetuximab in People With Colorectal Cancer
The purpose of this study is find out whether the combination of trastuzumab deruxtecan (T-DXd) and cetuximab is an effective treatment for participants with metastatic and/or unresectable colorectal cancer that expresses low…
- Conditions
- Colorectal Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
- Trial name
- NCT07691489
- Testing
- Fam-Trastuzumab Deruxtecan-Nxki
- Where
- 7 sites in United States
- Volunteers
- 27 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.