Clinical trials: Colorectal Neoplasms, completed
Colorectal Cancer, Liver Metastases
Carcinoembryonic Antigen-loaded Dendritic Cells in Advanced Colorectal Cancer Patients
Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system. As such they are currently used in clinical vaccination protocols in cancer patients.
- Trial name
- NCT00228189
- Testing
- CEA-loaded dendritic cell vaccine
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Colonic Neoplasms
Reduced Dose of Prophylactic Dexamethasone for Elderly Patients Receiving Moderate Emetogenic Chemotherapy
Feasibility study to evaluate the efficacy of reduced prophylactic dose of dexamethasone in elderly patients receiving moderate emetogenic chemotherapy
- Trial name
- NCT03177317
- Testing
- Dexamethasone
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Bundang Hospital
Lung Cancer, Breast Cancer
Measuring and Improving the Safety of Test Result Follow-Up
Improving communication is foundational to improving patient safety. Electronic health records (EHRs) can improve communication, but also introduce unique vulnerabilities.
- Conditions
- Lung Cancer, Breast Cancer, Colon Cancer, Bladder Cancer
- Trial name
- NCT04166240
- Testing
- SAFER TRACKS Intervention
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Colorectal Cancer
Development of a Serum Test for Colorectal Cancer Screening (COLODIAG préclinique)
Colorectal cancer (CRC) is a major public health problem, with 44,872 new cases per year in France (3rd most common cancer), and 17,684 deaths (2nd cause of death from cancer).
- Trial name
- COLODIAG pre (NCT04659018)
- Testing
- blood collection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Colon Polyp
Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance
In a prospective, randomized, controlled study, two methods (water method vs. air method) of performing colonoscopy will be compared in patients undergoing unsedated colonoscopy for CRC screening.
- Trial name
- NCT01383252
- Testing
- Water infusion in lieu of air insufflation, Air method
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Northern California Health Care System
Colon Cancer
BLI850-302: BLI850 vs an Approved Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
This is a randomized, parallel, multi-center, single-blind study, comparing BLI850 to an FDA approved bowel preparation in adult subjects undergoing colonoscopy.
- Trial name
- NCT00756548
- Testing
- BLI850, polyethylene glycol 3350 based bowel preparation
- Where
- 12 sites in United States
- Volunteers
- 386 people
- Sponsor
- Braintree Laboratories
Colorectal Cancer
Community Partnership for Telehealth Solutions to Convey Information and Enhance Care
Non-randomized, two-arm stepped-wedge trial of a multi-level colorectal cancer screening intervention.
- Trial name
- PRIME (NCT06542835)
- Testing
- Video text message, In-clinic CRC screening promotion, Mailed FIT
- Where
- United States
- Volunteers
- 15,128 people
- Sponsor
- University of Arizona
Colorectal Cancer, Screening Compliance
WhatsApp Reminder on FIT Compliance
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries.
- Conditions
- Colorectal Cancer, Screening Compliance, Fecal Immunochemical Test
- Trial name
- NCT03209765
- Testing
- WhatsApp reminder
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colon Cancer
PET Respiratory Gating to Detect Hepatic Metastasis in Patients With Colon Cancer
This study is to examine if there is improved sensitivity in detecting hepatic lesions using respiratory gating and if there is an improvement in confidence defining lesions as benign or malignant.
- Trial name
- NCT01401309
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Southwestern Regional Medical Center
Rectal Cancer, Rectosigmoid Cancer
Physical Activity in Rectal Cancer Survivors
The goal of this clinical trial is to test a telehealth-based personalized physical activity intervention in adult patients diagnosed with Stage I-III rectal cancer.
- Trial name
- NCT06435975
- Testing
- Physical Activity, Survey, Telehealth Lifestyle Coaching
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colorectal Cancer
Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer
RATIONALE: Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as panitumumab, can block tumor growth in different ways.
- Trial name
- NCT00940316
- Testing
- panitumumab, erlotinib hydrochloride, irinotecan hydrochloride
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Northwestern University
Colorectal Cancer, Adenomatous Polyps
Exploratory Study of a Novel Based rbcDNA Liquid Biopsy Technique for Colorectal Cancer Early Detection
Exploration of a novel rbcDNA liquid biopsy technique for early detection of colorectal cancer is a promising development in the field of disease diagnosis and screening.
- Conditions
- Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
- Trial name
- NCT05875584
- Testing
- rbcDNA test
- Where
- China
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Lynch Syndrome, Endometrial Cancer
Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
Given that there is a significant prevalence of Lynch syndrome among patients with endometrial cancer (about 5% of patients with endometrial cancer), and given there is a known risk of endometrial cancer among patients with…
- Conditions
- Lynch Syndrome, Endometrial Cancer, Endometrial Hyperplasia, Mismatch Repair Deficiency
- Trial name
- NCT05257057
- Testing
- Immunohistochemical staining
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Colorectal Cancer Screening
Test Up Now Education Program
This study will test the effectiveness of an outreach strategy to increase colorectal cancer screening in African Americans. The investigators will recruit 250 African Americans ages 45-64 years who are not up-to-date with…
- Trial name
- TUNE-UP (NCT04304001)
- Testing
- Community Health Advisor, Usual care
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Florida A&M University
Colorectal Cancer Metastatic
Predictive Value of Drug Sensitivity Testing Tumorspheres From Patients With Metastatic Colorectal Cancer
The purpose of the present study is to investigate the benefit of anti-cancer therapy administered on the basis of drug sensitivity testing. This concerns colorectal cancer patients who have previously received standard treatment.
- Trial name
- NCT03251612
- Testing
- Based on sensitivity analysis
- Where
- 4 sites in Denmark, Germany
- Volunteers
- 90 people
- Sponsor
- Vejle Hospital
Colorectal Cancer Metastatic
Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy
This study is being done to look at the safety and response to the combination of two investigational drugs, tremelimumab and durvalumab, when given after radiation therapy for patients with microsatellite stable (MSS) metastatic…
- Trial name
- NCT03007407
- Testing
- durvalumab, Tremelimumab
- Where
- 18 sites in United States
- Volunteers
- 33 people
- Sponsor
- NSABP Foundation Inc
Metastatic Triple Negative Breast Cancer, Metastatic Colorectal Cancer
Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases
Approximately 36 DLT-evaluable subjects will be enrolled in this study. The locations of the study will be in the United States, Australia, Europe and Switzerland.
- Trial name
- NCT03256344
- Testing
- Talimogene Laherparepvec, Atezolizumab
- Where
- 17 sites in United States, Australia and 4 more
- Volunteers
- 36 people
- Sponsor
- Amgen
Colorectal Neoplasm
Oxaliplatin and S-1 (OS) Versus Oxaliplatin and Capecitabine (XELOX) for Advanced Colorectal Cancer
The aim of this study is to compare the activity and safety of Oxaliplatin and S-1 (OS) and Oxaliplatin and Capecitabine (XELOX) in patients with advance or recurrent colorectal cancer.
- Trial name
- NCT00677144
- Testing
- OS (oxalipaltin+S-1), XELOX (oxalipaltin+capecitabine)
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Hallym University Medical Center
Colorectal Neoplasms
EffectiveNess of Low Dose Aspirin in GastrointEstinal Cancer Prevention - Taiwan
The study evaluates the protective effect of low-dose aspirin use on gastrointestinal cancers (colorectal, esophageal and gastric cancers) in long-term users, episodic users and non-users of aspirin in Taiwan.
- Trial name
- ENgAGE-Taiwan (NCT03579732)
- Testing
- Aspirin (Acetylsalicylic Acid, BAYE4465), No drug
- Where
- Taiwan
- Volunteers
- 4,710,504 people
- Sponsor
- Bayer