Clinical trials: Colorectal Surgical Procedure Outcomes
Colorectal Cancer, Oncologic Complications and Emergencies
Emergency Curative Resection of Colorectal Cancer
The feasibility and efficacy of emergency curative resection of complicated colorectal cancer is still controversial. This prospective study aim is to assess surgical and oncologic outcomes after emergency compared to elective…
- Trial name
- NCT04288284
- Testing
- Curative resection of colorectal cancer
- Volunteers
- 215 people
- Sponsor
- University of Alexandria
Perianal Abscess, Anal Fistula
Machine Learning-Based Risk Stratification for Fistula Formation After Perianal Abscess Drainage
This prospective cohort study investigates the influence of provider experience and drainage location on fistula formation within 6 months following perianal abscess drainage.
- Trial name
- PRISM (NCT07019532)
- Volunteers
- 450 people
- Sponsor
- Gumushane State Hospital
Colorectal Cancer, Colorectal Neoplasms
PRIORITY-CONNECT 2 Trial
Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal…
- Trial name
- PC2 (NCT06976710)
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 31 sites in Australia
- Volunteers
- 564 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Colorectal Cancer, Surgery
A Mobile Application to Improve Postoperative Outcomes in Colorectal Cancer
The unplanned readmission rate after colorectal cancer surgery is still high, despite the implementation of enhanced recovery programs.
- Trial name
- RAISe-Care (NCT06302751)
- Testing
- Care 4 Today ® (Johnson and Johnson) mobile app
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Istituto Clinico Humanitas
Financial Benefit, Colorectal Cancer
Emilia-Romagna Surgical Colorectal Cancer Audit- ESCA
Focus of this project is to evaluate the possible financial benefit resulting from an optimization of surgical outcomes throughout a collaborative and systematic auditing activity.The primary objective of this analysis is to…
- Conditions
- Financial Benefit, Colorectal Cancer, Surgery, Auditing Activity
- Trial name
- ESCA (NCT03982641)
- Testing
- all colorectal cancer surgical procedures
- Where
- 9 sites in Italy
- Volunteers
- 1,400 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Colorectal Cancer Metastatic, Surgical Procedure, Unspecified
Perioperative Outcomes of Simultaneous Colorectal and Liver Resections
The use of a simultaneous resection in patients with synchronous colorectal liver metastases has increased over the past decades.
- Trial name
- SIMULT (NCT05475041)
- Testing
- Major liver resection, Technically major liver resection
- Where
- Italy
- Volunteers
- 766 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Liver Neoplasms, Sarcopenia
Impact of Sarcopenia on Postoperative Outcomes of Patients Undergoing Liver Resection
The investigators will investigate the impact of different biometric parameters (Body mass index, sarcopenia, lean muscle mass, hand-grip strength, gait speed, fat composition) on the postoperative outcomes of patients undergoing…
- Conditions
- Liver Neoplasms, Sarcopenia, Postoperative Complications
- Trial name
- NCT03630978
- Testing
- Liver resection
- Where
- Italy
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- San Camillo Hospital, Rome
Liver Metastases From Colorectal Cancer
Liver-First, Bowel-First, or Simultaneous Resection for Synchronous Colorectal Liver Metastases: Outcomes, Quality of Life, and Cost-Effectiveness
The goal of this observational study is to learn about treatment outcomes, quality of life, and healthcare costs in patients with colorectal cancer who have liver metastases detected at the same time as their primary tumor…
- Trial name
- OPTIMAL (NCT07564284)
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Major Surgery
Long-term Enlarged Survival After an Enhanced Recovery Protocol (LESAS).
The main objective of this study is to analyze the impact on three years survival of an enhanced recovery program (PRI) after radical surgery for colorectal cancer.
- Trial name
- LESAS (NCT04305314)
- Testing
- PRI (Enhanced Recovery after surgery protocol)
- Where
- 12 sites in Spain
- Volunteers
- 750 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Inflammatory Bowel Diseases
Preoperative Oral ImmunoNuTrition to Improve Surgical Outcomes for IBD Patients (PINT)
The central focus of this trial is to understand the effectiveness of Preoperative Immunonutrition (PINT) in improving surgical outcomes for patients with inflammatory bowel disease (IBD).
- Trial name
- PINT (NCT03333148)
- Testing
- Nestle IMPACT Immunonutrition, Arm B- Standard of Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Colorectal Cancer
Neutrophil-to-Lymphocite Ratio (NLR) and C-reactive Protein (CRP) as New Markers in Diagnosis and Prediction of Colorectal Cancer
Colorectal cancer (CRC) is the second leading cause of cancer-related death in the Western world. Overall survival (OS) remains poor, with 50% estimated 5-year survival.
- Trial name
- NelyCre (NCT05129046)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Crohn Disease, Colorectal Cancer
Colorectal Cancer in Crohn's Disease
Retrospective multicentre study. All patients with a diagnosis of Crohn's disease (CD) and operated for colorectal cancer (CRC) between 01/01/2010 and 01/01/2020 will be included in the dataset.
- Conditions
- Crohn Disease, Colorectal Cancer, Inflammatory Bowel Diseases
- Trial name
- NCT04654494
- Testing
- Total proctocolectomy, Total colectomy, Segmental colectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Rome Tor Vergata
Rectal Cancer
Chinese Surgical Robot Clinical Study on Rectectomy for Rectal Cancer
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Trial name
- NCT04836741
- Testing
- Micro Hand S robot, Laparoscope
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Rectal Cancer Recurrent, Pelvic Exenteration
Postoperative Results and Outcomes in Surgical Pelvic Exenteration
The purpose of this study is to evaluate the feasibility of a standardized surgical and care process for patients with locally advanced or recurrent rectal cancer that has spread to nearby pelvic organs.
- Conditions
- Rectal Cancer Recurrent, Pelvic Exenteration, Advanced Rectal Cancer
- Trial name
- PROS-PE (NCT07395505)
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Endometriosis, Rectum
Functional Outcomes of Surgical Management of Deep Endometriosis Infiltrating the Rectum
The purpose of this study is to determine whether performing colorectal resection in deep endometriosis infiltrating the rectum is responsible for a higher rate of postoperative digestive and urinary dysfunction when compared to…
- Trial name
- ENDORE (NCT01291576)
- Testing
- Rectal/colorectal segmental resection, Rectal nodule excision
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
Colorectal Cancer
Comparison of Probiotic Effects on the Outcomes of Patients After Colorectal Cancer Surgery
This clinical trial aims to compare the effects of administering Lactobacillus casei Shirota probiotics with Lactobacillus acidophilus on the outcomes of patients after colorectal cancer surgery.
- Trial name
- NCT07144475
- Testing
- Lactobacillus casei Shirota, Lactobacillus acidophilus
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Dharmais National Cancer Center Hospital
Endometriosis, Bowel Endometriosis
Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis
Colorectal resection is a standard surgical treatment of bowel deep infiltrating endometriosis (DIE). Nevertheless, concerns about different bowel functional outcomes related to radical surgery versus conservative surgery as…
- Conditions
- Endometriosis, Bowel Endometriosis, Constipation
- Trial name
- IRE-1 (NCT03565848)
- Testing
- Mesenteric vascular and nerve sparing surgery in laparoscopic segmental colorectal resection
- Volunteers
- 50 people
- Sponsor
- Università degli Studi dell'Insubria
Colorectal Neoplasms, Neoplasms Malignant
Clinical Outcomes of NOSES Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer
In this study, the investigators will compare the clinical outcomes of the natural orifice specimen extraction surgery versus traditional robotic-assisted surgery in the treatment of colorectal cancer.
- Conditions
- Colorectal Neoplasms, Neoplasms Malignant, Complication of Surgical Procedure, Robotic Surgical Procedures
- Trial name
- NOTR (NCT04230772)
- Testing
- Natural Orifice Specimen Extraction Surgery, Traditional Robotic-assisted Surgery
- Where
- 7 sites in China
- Volunteers
- 550 people
- Sponsor
- Taiyuan Li
Prognosis, Colorectal Cancer
The Impact of Colorectal Cancer Screening on Surgical Outcomes
This study aims to investigate the pathological characteristics and surgical outcomes of stage III CRC patients detected through screening.
- Conditions
- Prognosis, Colorectal Cancer, Screening
- Trial name
- NCT06416501
- Testing
- Mode of detection
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Fudan University
Liver Cancer, Pancreas Cancer
PRIORITY-CONNECT 2 Pilot Trial
The provision of preoperative interventions (prehabilitation: including exercise, nutrition, and psychological treatment) have been reported to reduce postoperative complications by as much as 50% and reduce hospital stay by up…
- Conditions
- Liver Cancer, Pancreas Cancer, Oesophageal Cancer, Gastric Cancer
- Trial name
- NCT06212700
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 2 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)