Clinical trials: Colorectal Ulcers
Ulcerative Colitis, Crohn's Disease
Study on Cannabinoid Receptor Expression in Gastrointestinal Diseases
The purpose of the study is to investigate phospholipid ligands and their receptors in inflammatory bowel diseases and colon cancer.
- Conditions
- Ulcerative Colitis, Crohn's Disease, Colon Cancer
- Trial name
- NCT02735941
- Where
- Austria
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Ulcerative Colitis, Ileal Pouch
MRI Anastomotic Integrity of Pelvic Intestinal Anastomoses
This protocol describes using an MRI-Enema technique to assess the integrity of colorectal anastomoses when compared to fluoroscopic water soluble contrast enema, and provides information the participant recruitment process…
- Conditions
- Ulcerative Colitis, Ileal Pouch, Anastomotic Leak
- Trial name
- NCT04719169
- Testing
- Dynamic MRI enema, Fluoroscopic enema
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- London North West Healthcare NHS Trust
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Anastomotic Leak, Colorectal Cancer
The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study
The Prediction of Anastomotic Insufficiency risk after Colorectal surgery (PANIC) study aims to establish a machine-learning-based application that allows for accurate preoperative prediction of patients at risk for anastomotic…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Diverticulosis, Crohn Disease
- Trial name
- NCT04985981
- Where
- 2 sites in Switzerland
- Volunteers
- 11,000 people
- Sponsor
- Michel Adamina, MD
Colonic Diseases, Rectal Diseases
Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery
The purpose of this research is to compare two different standard of care surgical methods for the following large bowel (colon) procedures: laparoscopic right colectomy, total colectomy, and left colectomy.
- Trial name
- NCT00487409
- Testing
- Bipolar electrosurgical generator and instruments, Disposable stapling instruments
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University Hospitals Cleveland Medical Center
Colon Carcinoma, Dysplasia in Crohn Disease
Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia
This pilot, randomized phase I/II trial studies how well inositol works in preventing colorectal cancer in patients with abnormal cells (dysplasia) associated with inflammation of the colon (colitis).
- Conditions
- Colon Carcinoma, Dysplasia in Crohn Disease, Low Grade Dysplasia in Ulcerative Colitis, Rectal Carcinoma
- Trial name
- NCT01111292
- Testing
- Inositol
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- National Cancer Institute (NCI)
Ulcerative Colitis
Linked Color Imaging vs. White Light for Colorectal Dysplasia in Ulcerative Colitis
The purpose of the study is to determine whether a new colonoscopic viewing technique called Linked color imaging(LCI) helps endoscopists detect more dysplasia lesions in ulcerative colitis patients than conventional colonoscopy…
- Trial name
- NCT02772406
- Testing
- Linked Color Imaging, white light imaging
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Rectal Cancer, Ulcerative Colitis
Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study
Clinical experience show limited effect of the drug Loperamide used to decrease output in stoma patients. Therefore the investigators see the need for a randomized blinded clinical trial to determine the effect of Loperamide…
- Conditions
- Rectal Cancer, Ulcerative Colitis, Short Bowel Syndrome
- Trial name
- NCT02266849
- Testing
- Loperamide
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Colorectal Ulcers, Computer-aided System
Accuracy of Computer-aided (CADx) System in Real-time Characterization of Colorectal Ulcerative Diseases
The goal of this observational study is to test the diagnostic accuracy of the newly developed CADx system in predicting the histopathology of colorectal ulcers when compared to expert endoscopists.
- Trial name
- NCT06207825
- Testing
- Test images and videos
- Volunteers
- 495 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Colorectal Ulcers, Computer-aided System
A Computer-aided (CADx）System in Real-time Characterization of Colorectal Ulcerative Diseases
The goal of this observational study is to construct and validate a Computer-aided (CADx）System in Real-time Characterization of Colorectal Ulcrerative Diseases.
- Trial name
- NCT06208982
- Testing
- Colonoscopy images and videos
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Colon Cancer, Diverticulitis
General Surgical Outcomes Quality Improvement Database (UH-SOCRATES)
A database has been established to track the outcomes of all cases performed in the University Hospitals Department of Surgery in an effort to improve quality of surgical performance and case management.
- Conditions
- Colon Cancer, Diverticulitis, Colorectal Polyps, Crohn's Disease
- Trial name
- SOCRATES (NCT00622557)
- Where
- United States
- Volunteers
- 200,000 people
- Sponsor
- University Hospitals Cleveland Medical Center
Ulcerative Colitis, Colon Cancer
Study of Effects of L-Arginine in Colitis and Colon Cancer
The purpose of this study is to look at the importance of L-Arginine in the digestive tract. L-Arginine is an amino acid and is important in making proteins within the cell.
- Trial name
- NCT01091558
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Inflammatory Bowel Diseases, Crohn Disease
Digestive Biobank for Exploring Microbiota-host Interactions
Constitution of a biobank of tissues, whole blood and plasma samples and stools to identify markers associated with treatment response, postoperative morbidity including neuro-cognitive and mood complications and prognosis of…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Colorectal Cancer
- Trial name
- BiomHost (NCT05704413)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ulcerative Colitis, Familial Polyposis
An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery
This will be a prospective, multi-center, randomized, single blind study to collect and evaluate post-market clinical data on the SprayShield Adhesion Barrier System as an adjuvant to good surgical technique for the reduction of…
- Trial name
- NCT01002287
- Testing
- SprayShield Adhesion Barrier System, Good Surgical Technique Alone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Integra LifeSciences Corporation
Inflammatory Bowel Disease, Colorectal Cancer
Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease
Build a collection of fecal microbiota in order to determine the characteristics of gut microbiota associated with colorectal cancer in Inflammatory bowel disease (IBD).
- Trial name
- DYSCOLIC (NCT02726243)
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ulcerative Colitis (UC), Colorectal Cancer (CRC)
Smart Pill for Measuring Gut Health in Colon Inflammation and Colon Cancer
The goal of this observational pilot study with invasive measurements is to explore whether an ingestible sensor pill can be of use in diagnosis or monitoring of disease in patients with ulcerative colitis or colorectal cancer.
- Trial name
- SPIRIT (NCT07046468)
- Testing
- Ingestion of sensor capsule (twice), Device evaluation questionnaire, Wearing device
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Radboud University Medical Center
Crohn Disease, Polyposis
Clinical Database of Colorectal Robotic Surgery
Evaluation of robot Da Vinci Xi by determining its learning curve.The operating time will be defined by patient then the operating average will be calculated.
- Conditions
- Crohn Disease, Polyposis, Ulcerative Colitis, Diverticulitis
- Trial name
- ROBOT CR (NCT04013152)
- Testing
- Clinical database
- Where
- 4 sites in France
- Volunteers
- 1,800 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Colitis,Ulcerative, Adenomatous Polyposis Coli
Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients
The purpose of this registry is to collect information about patients in which a pouch has been created to improve in the future the quality of the surgery of the pouch.
- Conditions
- Colitis,Ulcerative, Adenomatous Polyposis Coli, Reservoir, Ileoanal
- Trial name
- KOPOF (NCT01604564)
- Where
- Belgium
- Volunteers
- 207 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Inflammatory Bowel Diseases, Colon Dysplasia
High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
Inflammatory Bowel Disease (IBD) involving the colon is a known risk for colon cancer. There are two standards-of-care colonoscopy techniques used for screening all patients who suffer from IBD for more than eight years.
- Conditions
- Inflammatory Bowel Diseases, Colon Dysplasia, Ulcerative Colitis, Crohn Colitis
- Trial name
- NCT04191655
- Testing
- High Definition Colonoscopy, Dye Spraying Chromocolonoscopy
- Where
- 2 sites in United States
- Volunteers
- 211 people
- Sponsor
- Beth Israel Deaconess Medical Center
Rectal Neoplasms, Colitis, Ischemic
Anterior Perineal Plane for Ultra Low Anterior Resection of the Rectum
Anal sphincter preserving operations are now commonplace for both cancer and non-cancerous rectal diseases. However, this has not always been the case and this development has been facilitated by the invention of circular…
- Conditions
- Rectal Neoplasms, Colitis, Ischemic, Colitis, Ulcerative
- Trial name
- APPEAR (NCT00534131)
- Testing
- Standard abdominal approach for rectal excision, APPEAR Procedure, Proctectomy
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Queen Mary University of London