Clinical trials: Combat Related Symptoms, active
Chronic Pain, PTSD - Post Traumatic Stress Disorder
Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans
Veterans in Canada are twice as likely as the general population to experience chronic pain. This pain is often linked to post-traumatic stress disorder (PTSD), and both have a major impact on their quality of life.
- Conditions
- Chronic Pain, PTSD - Post Traumatic Stress Disorder, Quality of Life (QOL)
- Trial name
- VR & CN-NINM (NCT07137845)
- Testing
- Virtual reality, Cranial nerve non-invasive neuromodulation (CN-NINM)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Borderline Personality Disorder (BPD), PTSD - Post Traumatic Stress Disorder
Pilot Study for the Evaluation of a New Psychotherapeutic Treatment for Borderline Personality Disorder Patients With Post-traumatic Stress Symptoms
Borderline Personality Disorder (BPD) is a serious mental health condition that often co-occurs with Complex PTSD (CPTSD), making treatment more challenging.
- Trial name
- MBT-TF (NCT07305155)
- Testing
- Standard Mentalization-Based Treatment, Trauma-Focused Mentalization-Based Treatment
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Eva Rüfenacht
Chronic Pain, PTSD - Post Traumatic Stress Disorder
Virtual Reality and Cranial Nerve Neuromodulation to Manage Chronic Pain
In Canada, veterans suffer from chronic pain at twice the rate of the general population. This pain is often linked to post-traumatic stress disorder (PTSD), and both have a major impact on their quality of life.
- Trial name
- VR & CN-NINM (NCT07065396)
- Testing
- Virtual reality, Cranial nerve non-invasive neuromodulation (CN-NINM)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Université de Sherbrooke
Burn Scar Pain, Neuropathic Pain
Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study
Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue.
- Conditions
- Burn Scar Pain, Neuropathic Pain, Combat-Related Burn Injury, Scar-Related Pain
- Trial name
- US-SCAR-PAIN (NCT07438769)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
PTSD, Military Activity
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members.
- Conditions
- PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder
- Trial name
- NCT05414708
- Testing
- Art Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Walter Reed National Military Medical Center
New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
The goal of this clinical trial is to find out whether two existing medications-anakinra and tocilizumab-can effectively treat a rare and life-threatening brain condition called NORSE (New-Onset Refractory Status Epilepticus).
- Conditions
- New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus, Febrile Infection-Related Epilepsy Syndrome (FIRES)
- Trial name
- COMBAT-NORSE (NCT07281027)
- Testing
- Anakinra, Tocilizumab, Standard medical treatment
- Where
- 33 sites in United States, Canada and 5 more
- Volunteers
- 438 people
- Sponsor
- Yale University
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Low Back Pain, Amputation
The Association Between Amputation Level and Chronic Low Back Pain After Combat-Related Amputation
Patients with combat-related lower limb amputations frequently experience chronic low back pain during long-term rehabilitation and prosthetic use.
- Trial name
- LEVEL-BACK (NCT07626294)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
PTSD - Post Traumatic Stress Disorder
The Effect of Using the Combat Attention App on the Risk of Post-traumatic Symptoms
Military service and reserve duty in combat units entails exposure to traumatic events that require mental adjustment. In light of the results of controlled studies that proved the effectiveness an response-time based mechanized…
- Trial name
- NCT06710145
- Testing
- Combat Attention Training
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Tel Aviv University
Depression - Major Depressive Disorder, Anxiety
Deaf CBT-TS to Reduce Suicide Risk
The goal of this clinical trial is to learn if a short, Zoom-based intervention, Cognitive Behavioral Therapy for Treatment-Seeking for Deaf Individuals (Deaf CBT-TS) can change beliefs about mental health treatment and increase…
- Conditions
- Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia
- Trial name
- NCT07279363
- Testing
- Deaf CBT-TS
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Rochester
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
HBOT Effects on First Responders' Cognition and Well-Being
The goal of this study is to examine changes in cognitive functioning and post-concussive symptoms following hyperbaric oxygen therapy (HBOT) in current and former first responders with a history of traumatic brain injury.
- Conditions
- Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT07852728
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
PTSD - Post Traumatic Stress Disorder, PTSD
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
The Redefine Study (COMP202) is testing COMP360 to see if it may reduce post-traumatic stress disorder (PTSD) symptoms when administered alongside monitoring and support from a trained study team.
- Conditions
- PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
- Trial name
- Redefine (NCT07570654)
- Testing
- COMP360 psilocybin
- Where
- 17 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- COMPASS Pathways
Post Traumatic Stress Disorder PTSD
Psychosocial Factors and Efficacy of Remote Cognitive Remediation for Post-Traumatic Stress Disorder
The goal of this clinical trial is to evaluate whether computer-based brain training can help adults with post-traumatic stress disorder (PTSD).
- Trial name
- NCT07309302
- Testing
- Cognitive Remediation Training, Control Group
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Université du Québec a Montréal
Obesity and Obesity-related Medical Conditions, Spinal Cord Injury, Chronic
UTSW NORC Pilot Spinal Cord Injury Dietary Program
The goal of this observational study is to learn about the effects of a 9-week dietician-guided program modified from the National Diabetic Prevention Program (modified DPP-diet) in people with spinal cord injury on body…
- Trial name
- NCT06924177
- Testing
- Telehealth with dietician
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Burnout, Professional, Stress, Psychological
Foundational Programs to Combat Clinician Stress
This is a prospective, randomized, controlled clinical trial in which clinicians from University of Pennsylvania Health Systems (UPHS) including Penn Medicine- Lancaster General Health (LGH) and Massachusetts General Hospital…
- Conditions
- Burnout, Professional, Stress, Psychological, Stress, Physiological, Psychological Well-Being
- Trial name
- FACCTS (NCT07220421)
- Testing
- Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation, Health Education Program (HEP)
- Where
- 6 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Pain, Chronic Pain
Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury
Combat-related traumatic brain injury (cTBI), particularly blast-related injury, is frequently associated with the development of persistent and disabling chronic pain.
- Conditions
- Pain, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- TBI-Pain (NCT07424248)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Traumatic Brain Injury, Insomnia
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and…
- Conditions
- Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress
- Trial name
- NCT05663034
- Testing
- Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Personality Disorder, Borderline, Personality Trait
Bridging Affect Consciousness, Mentalization and Trauma- Exploring an Integrative Treatment Approach for Personality Disorder (PD).
Study background: Specialized Group Outpatient Clinic within specialist mental health services, tailoring two year group treatment programmes for severe Avoidant PD (AvPD) and Borderline PD (BPD) with Affect Consciousness (AC)…
- Conditions
- Personality Disorder, Borderline, Personality Trait, Personality Disorder, Personality Type
- Trial name
- NCT06983002
- Testing
- Experimental group: AC-group therapy intervention., Control group 1: Body Awareness Group., Control group 2: Art Psychotherapy group.
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Helse Stavanger HF
Post Traumatic Stress Disorder PTSD, Suicidal Ideation
Deep TMS for PTSD With Suicidal Ideation
The goal of this clinical trial is to evaluate whether deep transcranial magnetic stimulation (DTMS) using the H1-coil can safely and effectively reduce suicidal ideation in adults diagnosed with post-traumatic stress disorder…
- Trial name
- DTMS-PTSD-SI (NCT07880340)
- Testing
- Deep Transcranial Magnetic Stimulation (DTMS)
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- D.R. Rut Zaks OHAYON