Clinical trials: Combat Stress Disorders
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Posttraumatic Stress Disorder
Variable-length Cognitive Processing Therapy for Combat-Related PTSD
The primary goal of this study is to improve the overall efficacy of cognitive processing therapy-cognitive-only version (CPT-C) in a sample of 130 active-duty service members through a variable length treatment.
- Trial name
- NCT02313818
- Testing
- Cognitive Processing Therapy-Cognitive Only
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Duke University
PTSD - Post Traumatic Stress Disorder
First-Line Intervention for PTSD - Intensive Treatment
The goal of this clinical trial is to learn if an intensive program can treat post-traumatic stress disorder (PTSD) in adults getting treatment for the first time, and whether it has lower societal costs.
- Trial name
- FLIP-IT (NCT06700590)
- Testing
- Intensive Treatment, Treatment as usual
- Where
- 4 sites in Netherlands
- Volunteers
- 186 people
- Sponsor
- ARQ National Psychotrauma Centre
PTSD
Prevention of Combat-related PTSD Using Attention Bias Modification (ABM): A Randomized Controlled Trial
Military deployment to combat zones involves exposure to trauma at a higher than average rate and therefore presents a unique opportunity to study predisposing factors to posttraumatic stress reactions and test strategies…
- Trial name
- NCT01723215
- Testing
- Active ABMT8, Active ABMT4
- Where
- Israel
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
PTSD - Post Traumatic Stress Disorder, Sexual Abuse
Evaluation of Restory - an Online Trauma Treatment for Victims of Sexual Abuse
This project aims to evaluate Restory - a newly developed anonymous, iCBT prolonged exposure therapy program specifically tailored for victims of sexual abuse - using a pre-registered randomized controlled trial with waitlist…
- Trial name
- NCT07610187
- Testing
- Restory
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Posttraumatic Stress Disorder
Effect of Prazosin on Neurophysiology and Cognition in Post-Traumatic Stress Disorder (PTSD)
In this study, the investigators are looking at how PTSD affects things such as memory, attention, reaction to sounds, eye movements, and heart rate.
- Trial name
- NCT00890643
- Testing
- prazosin hydrochloride
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder
Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD
The purpose of this study is to examine the benefits of combining repetitive Transcranial Magnetic Stimulation (rTMS) coupled with Cognitive Processing Therapy (CPT) in treating combat-related Posttraumatic Stress Disorder (PTSD)…
- Trial name
- NCT03932773
- Testing
- Active rTMS, Cognitive Processing Therapy
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- The University of Texas at Dallas
Stress Disorders, Combat Disorders
FOCUS-CI: A Preventive Intervention With Children and Families of the Combat Injured
The purpose of this study is to implement a unique evidence-based intervention program to help military families deal with the critical issue of combat injury and its impact on current and future family health and functioning.
- Conditions
- Stress Disorders, Combat Disorders, Traumatic Stress Disorders
- Trial name
- FOCUS-CI (NCT01062022)
- Testing
- Standard of Care, FOCUS-CI
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Stress Disorders, Post-Traumatic
Treatment of Formerly Abducted Children (FAC) in Uganda
In the aftermath of traumatic experiences like natural disasters or man-caused traumatic events, such as war experiences, a substantial part of the affected individuals develop a number of psychological symptoms.
- Trial name
- NCT00552006
- Testing
- Narrative Exposure Therapy, Academic Counseling
- Where
- Uganda
- Volunteers
- 85 people
- Sponsor
- University of Konstanz
Combat Disorders, Stress Disorders, Post-Traumatic
Quetiapine Augmentation for Treatment-resistant PTSD
The purpose of this study is to compare the response of veterans with PTSD without an optimal response to paroxetine to quetiapine augmentation versus placebo.
- Trial name
- NCT00292370
- Testing
- Open Label (OL) Paroxetine, Quetiapine
- Where
- 3 sites in United States
- Volunteers
- 124 people
- Sponsor
- VA Office of Research and Development
PTSD - Post Traumatic Stress Disorder
Diet and Microbiome Interactions: Application in Posttraumatic Stress Disorder in Adults Consuming Vegetable Drinks
The gut microbiome has been shown to impact various facets of human health, including mental health. Studies have shown that populations with more agrarian lifestyles tend to have fewer chronic diseases and mental health issues…
- Trial name
- DMAPS (NCT07107269)
- Testing
- Low diversity plant beverage (Functional Food Intervention), High diversity plant beverage (Functional Food Intervention)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Colorado State University
PTSD - Post Traumatic Stress Disorder, Depression
Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals
This study will examine the effects of Eye Movement Desensitization and Reprocessing (EMDR) group therapy on adults who experienced the April 2025 Silivri earthquake in Turkey.
- Conditions
- PTSD - Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Sleep Quality
- Trial name
- NCT07206381
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Group Therapy
- Volunteers
- 40 people
- Sponsor
- Istanbul Galata University
Stress Disorders, Post Traumatic, Trust
Neuroimaging the Impact of Treatment on Neural Substrates of Trust in Post-Traumatic Stress Disorder (PTSD)
Traumatic experiences can have a profound negative effect on the lives and well-being of both the people who experience them and their loved ones.
- Trial name
- NCT01244477
- Testing
- Group CPT-C
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorders, Combat Disorders
Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
In comparison to the general population, U.S. military and Veterans are at an increased risk for developing both substance use disorders (SUD) and Post Traumatic Stress Disorder (PTSD).
- Conditions
- Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
- Trial name
- COPE (NCT01338506)
- Testing
- Concurrent Treatment with Prolonged Exposure (COPE)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Medical University of South Carolina
PTSD - Post Traumatic Stress Disorder
Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD
The goal of this study is to determine how non-invasive brain stimulation (delivered through the ear called vagus nerve stimulation) affects fear learning processes in people who have experienced psychological trauma.
- Trial name
- SPARK-VNS (NCT06953388)
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wayne State University
Mood Disorders, Depression
Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders
Stress-related disorders are among the most prevalent and expensive medical consequences of participation in military operations.
- Conditions
- Mood Disorders, Depression, Combat Disorders, Stress Disorders
- Trial name
- NCT01216982
- Testing
- Lovaza, omega-3 fatty acid ethyl ester
- Where
- Iraq
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research